YRC Public Data Repository - Protein Structure Prediction

Protein:	ISPE_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	284 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ISPE_SHEON.

Description	E-value	Query Range	Subject Range
ISPE_SHELP - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4...	251.0	[0..1]	[281..1]
ISPE_PSEA7 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Pseudomonas aeruginosa (strain PA7) GN=ispE PE=...	249.0	[0..7]	[282..5]
ISPE_PSEAB - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=i...	249.0	[0..7]	[282..5]
ISPE_MANSM - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Mannheimia succiniciproducens (strain MBEL55E) ...	249.0	[0..6]	[283..19]
ISPE_PSEA8 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Pseudomonas aeruginosa (strain LESB58) GN=ispE ... gi\|126197817, gi... - gi\|84323295\|ref\|ZP_00971368.1\| COG1947: 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate syntha...	249.0	[0..7]	[282..5]
ISPE_PSEAE - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Pseudomonas aeruginosa GN=ispE PE=3 SV=2 ISPE_PSEAE - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO...	247.0	[0..7]	[282..5]
gi\|107099664 - gi\|107099664\|ref\|ZP_01363582.1\| hypothetical protein PaerPA_01000682 [Pseudomonas aeruginosa PACS2]	247.0	[0..7]	[282..5]
gi\|49083369 - gi\|49083369\|gb\|AAT51014.1\| PA4669 [synthetic construct]	247.0	[0..7]	[282..5]
ISPE_SHESM - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Shewanella sp. (strain MR-4) GN=ispE PE=3 SV=1	247.0	[0..1]	[284..1]
gi\|84317262, gi\|... - gi\|84317262\|ref\|ZP_00965713.1\| COG1947: 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate syntha...	247.0	[0..7]	[282..5]

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Predicted Domain #1

Region A:
Residues: [1-284]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQEISRNWP APAKLNLFLH INGRRSDGYH ELQTLFQFVD CCDQLDFRVT DTPELILHST  60
   61 MSAVVADSDN LILRAAKSLQ QATGFNGGAE IWLDKRLPMG GGLGGGSSDA ATTLVALNRL 120
  121 WNTQLSHDEL AAIGLKLGAD IPVFIHGFAA FAQGVGERLQ AVNPAELWYL VIAPDAHVST 180
  181 AAVFQDPLLP RNTPKLGLDT LLSQPWANDC QELVVSKYPQ VAKALGWLLE YAPSRMTGTG 240
  241 ACVFGEFSSQ QQALAALAKL PSDMQGFVAK GMNISPLIVR LNRP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.09691
Match:	1oj4A
Description:	Ternary complex of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity	1.9881460462076	bayes_pls_golite062009
catalytic activity	1.20658247466773	bayes_pls_golite062009
diphosphomevalonate decarboxylase activity	1.0502744466494	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: