YRC Public Data Repository - Protein Structure Prediction

Protein:	TRMB_ENTFA
Organism:	Enterococcus faecalis V583
Length:	214 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRMB_ENTFA.

Description	E-value	Query Range	Subject Range
TRMB_STRPJ - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1... TRMB_STRZP - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae (strain P1031) GN=trmB PE=3 SV=1 TRMB_STRPI - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae (strain Hungary19A-6) GN=trmB PE=... gi\|237650177 - gi\|237650177\|ref\|ZP_04524429.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae CCR... gi\|237821777 - gi\|237821777\|ref\|ZP_04597622.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae CCR... gi\|147930202, gi... - gi\|149021506\|ref\|ZP_01835561.1\| tRNA (guanine-N(7))-methyltransferase [Streptococcus pneumoniae SP23... TRMB_STRPN - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae GN=trmB PE=1 SV=1 gi\|147763380, gi... - gi\|149012575\|ref\|ZP_01833572.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae SP1... gi\|149005661, gi... - gi\|149005661\|ref\|ZP_01829400.1\| tRNA (guanine-N(7))-methyltransferase [Streptococcus pneumoniae SP18... TRMB_STRR6 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) GN=trm... gi\|149002222, gi... - gi\|149002222\|ref\|ZP_01827164.1\| tRNA (guanine-N(7))-methyltransferase [Streptococcus pneumoniae SP14... gi\|183573082, gi... - gi\|183573082\|gb\|EDT93610.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae SP195],... gi\|168485662, gi... - gi\|183571191\|gb\|EDT91719.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae CDC1087... gi\|183576911, gi... - gi\|183576911\|gb\|EDT97439.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae CDC3059... gi\|168490559, gi... - gi\|183574963\|gb\|EDT95491.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae CDC0288... gi\|147928965, gi... - gi\|148992339\|ref\|ZP_01822062.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pneumoniae SP9... TRMB_STRP2 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 746... TRMB_STRPN - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 /... TRMB_STRZJ - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pneumoniae (strain JJA) GN=trmB PE=3 SV=1	147.0	[0..1]	[211..1]
gi\|55737567, gi\|... - gb\|AAV63136.1\| conserved hypothetical protein, methyltransferase [Streptococcus thermophilus CNRZ106... TRMB_STRTD - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9) G... TRMB_STRT1 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus thermophilus (strain CNRZ 1066) GN=trmB PE=3... TRMB_STRT2 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus thermophilus (strain ATCC BAA-250 / LMG 1831...	146.0	[0..1]	[211..1]
TRMB_STRA5 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus agalactiae serotype V (strain ATCC BAA-611 /... TRMB_STRA1 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus agalactiae serotype Ia (strain ATCC 27591 / ... gi\|77414444, gi\|... - gi\|77414444\|ref\|ZP_00790595.1\| putative methyltransferase [Streptococcus agalactiae 515], gi\|7715948... gi\|77411670, gi\|... - gi\|77411670\|ref\|ZP_00788010.1\| methyltransferase, putative [Streptococcus agalactiae CJB111], gi\|771... gi\|77408776, gi\|... - gi\|77408776\|ref\|ZP_00785506.1\| methyltransferase, putative [Streptococcus agalactiae COH1], gi\|77172... gi\|77175021, gi\|... - gi\|77406352\|ref\|ZP_00783414.1\| methyltransferase, putative [Streptococcus agalactiae H36B], gi\|77175... gi\|76798052, gi\|... - gi\|76798052\|ref\|ZP_00780309.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus agalactiae 18RS... TRMB_STRA1 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus agalactiae serotype Ia GN=trmB PE=3 SV=1 TRMB_STRA3 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus agalactiae serotype III (strain NEM316) GN=t... TRMB_STRA3 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus agalactiae serotype III GN=trmB PE=3 SV=1 TRMB_STRA5 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus agalactiae serotype V GN=trmB PE=3 SV=1	146.0	[0..1]	[211..1]
TRMB_STRMU - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus mutans GN=trmB PE=3 SV=1 TRMB_STRMU - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA15...	142.0	[0..1]	[211..1]
gi\|48826237 - ref\|ZP_00287459.1\| COG0220: Predicted S-adenosylmethionine-dependent methyltransferase [Enterococcus... gi\|68196353, gi\|... - gi\|69244412\|ref\|ZP_00602828.1\| Conserved hypothetical protein 91 [Enterococcus faecium DO], gi\|68196...	142.0	[0..1]	[214..1]
gi\|66361276, gi\|... - gi\|66361277\|pdb\|1YZH\|B Chain B, Crystal Structure Of The Conserved Hypothetical Protein, Methyltrans...	141.0	[0..2]	[211..5]
TRMB_BACWK - tRNA (guanine-N(7)-)-methyltransferase OS=Bacillus weihenstephanensis (strain KBAB4) GN=trmB PE=3 SV... gi\|229062385, gi... - gi\|229062385\|ref\|ZP_04199701.1\| tRNA (guanine-N(7)-)-methyltransferase [Bacillus cereus AH603], gi\|2... gi\|229013906, gi... - gi\|229013906\|ref\|ZP_04171033.1\| tRNA (guanine-N(7)-)-methyltransferase [Bacillus mycoides DSM 2048],... gi\|228614037, gi... - gi\|229169432\|ref\|ZP_04297140.1\| tRNA (guanine-N(7)-)-methyltransferase [Bacillus cereus AH621], gi\|2...	140.0	[0..1]	[210..1]
TRMB_STRP6 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / ... TRMB_STRP6 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M6 GN=trmB PE=3 SV=1	139.0	[0..1]	[211..1]
TRMB_STRPG - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M5 (strain Manfredo) GN=tr... TRMB_STRPY - (P67504) tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (tRNA(m7G46)-methyltransferase) TRMB_STRP3 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / ... TRMB_STRP1 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M1 GN=trmB PE=3 SV=1 TRMB_STRP3 - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M3 GN=trmB PE=3 SV=1 TRMB_STRPC - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M12 (strain MGAS9429) GN=t... TRMB_STRPF - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M4 (strain MGAS10750) GN=t... TRMB_STRPD - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M2 (strain MGAS10270) GN=t... TRMB_STRPB - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M12 (strain MGAS2096) GN=t... TRMB_STRPQ - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M3 (strain SSI-1) GN=trmB ... TRMB_STRPM - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M28 (strain MGAS6180) GN=t... gi\|71854063, gi\|... - gi\|71911281\|ref\|YP_282831.1\| tRNA (guanine-N(7)-)-methyltransferase [Streptococcus pyogenes MGAS5005... TRMB_STRPM - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M28 GN=trmB PE=3 SV=1 gi\|13622780, gi\|... - gi\|15675576\|ref\|NP_269750.1\| tRNA (guanine-N(7))-methyltransferase [Streptococcus pyogenes M1 GAS], ... TRMB_STRPZ - tRNA (guanine-N(7)-)-methyltransferase OS=Streptococcus pyogenes serotype M49 (strain NZ131) GN=trmB...	139.0	[0..1]	[211..1]
gi\|228728963, gi... - gi\|229032355\|ref\|ZP_04188327.1\| tRNA (guanine-N(7)-)-methyltransferase [Bacillus cereus AH1271], gi\|... gi\|228771758, gi... - gi\|228987954\|ref\|ZP_04148060.1\| tRNA (guanine-N(7)-)-methyltransferase [Bacillus thuringiensis serov... gi\|228625268, gi... - gi\|229158310\|ref\|ZP_04286377.1\| tRNA (guanine-N(7)-)-methyltransferase [Bacillus cereus ATCC 4342], ... gi\|47565124, gi\|... - gi\|47565124\|ref\|ZP_00236167.1\| methyltransferase, putative [Bacillus cereus G9241], gi\|47557910\|gb\|E...	139.0	[0..1]	[210..1]

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Predicted Domain #1

Region A:
Residues: [1-214]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVRNRPGAA EYMAKYPQYV VEGPEKWQGK WQERFGNNHP IHIEIGSGKG RFIYEMAKAH  60
   61 PEINYIGIDM QLSILSIALD KLVADPLPNL QLLRVDGEAL TEYFAENEVD LIYLNFSDPW 120
  121 PKKKHEKRRL TYKNFLATDE IILKPNGEIH FKTDNQGLFE YSLSSFSKYG MIIERVWLDL 180
  181 HNSEFEGNIM TEYEEKFSSR GQRIYRVEAR FVAK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.0
Match:	1yzhA
Description:	Crystal Structure of the Conserved Hypothetical Protein, Methyltransferase from Streptococcus pneumoniae TIGR4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	4.06737071331982	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.9962750833086	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.74830027382001	bayes_pls_golite062009
RNA methyltransferase activity	3.6174490060285	bayes_pls_golite062009
rRNA methyltransferase activity	2.80578045927127	bayes_pls_golite062009
transferase activity	2.42370637689376	bayes_pls_golite062009
tRNA methyltransferase activity	2.15176183511624	bayes_pls_golite062009
catalytic activity	1.62377578202456	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	0.72946673557525	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	0.62885479399246	bayes_pls_golite062009
N-methyltransferase activity	0.49575399394607	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	0.355378060639199	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: