YRC Public Data Repository - Protein Structure Prediction

Protein:	UPPS_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	237 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UPPS_COXBU.

Description	E-value	Query Range	Subject Range
UPPS_THETN - Undecaprenyl pyrophosphate synthase OS=Thermoanaerobacter tengcongensis GN=uppS PE=3 SV=1 gi\|223488732, gi... - gi\|254479462\|ref\|ZP_05092789.1\| undecaprenyl pyrophosphate synthetase 1 [Carboxydibrachium pacificum... ISPT_CALS4 - Isoprenyl transferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM ...	366.0	[0..2]	[231..18]
gi\|170714048, gi... - gi\|170714048\|gb\|EDT26230.1\| undecaprenyl diphosphate synthase [Clostridium perfringens CPE str. F496... gi\|110676017, gi... - gi\|110801370\|ref\|YP_696383.1\| undecaprenyl diphosphate synthase [Clostridium perfringens ATCC 13124]... gi\|182380984, gi... - gi\|182380984\|gb\|EDT78463.1\| undecaprenyl diphosphate synthase [Clostridium perfringens NCTC 8239], g... ISPT_CLOPE - Isoprenyl transferase OS=Clostridium perfringens (strain 13 / Type A) GN=uppS PE=3 SV=1 gi\|169299227, gi... - gi\|169342721\|ref\|ZP_02863762.1\| undecaprenyl diphosphate synthase [Clostridium perfringens C str. JG... gi\|177907477, gi... - gi\|182627140\|ref\|ZP_02954855.1\| undecaprenyl diphosphate synthase [Clostridium perfringens D str. JG... gi\|110803535, gi... - gi\|110803535\|ref\|YP_698983.1\| undecaprenyl diphosphate synthase [Clostridium perfringens SM101], gi\|... gi\|168208113, gi... - gi\|170660606\|gb\|EDT13289.1\| undecaprenyl diphosphate synthase [Clostridium perfringens E str. JGS198... UPPS_CLOPE - Undecaprenyl pyrophosphate synthase OS=Clostridium perfringens GN=uppS PE=3 SV=1 gi\|170710581, gi... - gi\|170710581\|gb\|EDT22763.1\| undecaprenyl diphosphate synthase [Clostridium perfringens B str. ATCC 3...	357.0	[0..2]	[232..23]
ISPT1_NOSS1 - Isoprenyl transferase 1 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=uppS1 PE=3 SV=1 gi\|25314096 - pir\|\|AD2180 undecaprenyl pyrophosphate synthetase [imported] - Nostoc sp. (strain PCC 7120)	357.0	[0..1]	[231..19]
gi\|23128548, gi\|... - gi\|23128548\|ref\|ZP_00110393.1\| COG0020: Undecaprenyl pyrophosphate synthase [Nostoc punctiforme PCC ...	356.0	[0..1]	[231..19]
gi\|167037632, gi... - gi\|76796454\|ref\|ZP_00778816.1\| Di-trans-poly-cis-decaprenylcistransferase [Thermoanaerobacter ethano... gi\|241903183, gi... - gi\|241903183\|ref\|ZP_04787910.1\| undecaprenyl diphosphate synthase [Thermoanaerobacter brockii subsp....	355.0	[0..2]	[231..20]
ISPT_ANAVT - Isoprenyl transferase OS=Anabaena variabilis (strain ATCC 29413 / PCC 7937) GN=uppS PE=3 SV=2	355.0	[0..1]	[231..19]
gi\|166854533, gi... - gi\|167040293\|ref\|YP_001663278.1\| undecaprenyl diphosphate synthase [Thermoanaerobacter sp. X514], gi... gi\|242258359, gi... - gi\|242258359\|ref\|ZP_04803172.1\| undecaprenyl diphosphate synthase [Thermoanaerobacter sp. X513], gi\|...	353.0	[0..2]	[231..20]
gi\|67922228, gi\|... - gi\|67922228\|ref\|ZP_00515742.1\| Di-trans-poly-cis-decaprenylcistransferase [Crocosphaera watsonii WH ...	351.0	[0..3]	[232..52]
ISPT_THEEB - Isoprenyl transferase OS=Thermosynechococcus elongatus (strain BP-1) GN=uppS PE=3 SV=1 UPPS_SYNEL - Undecaprenyl pyrophosphate synthetase OS=Synechococcus elongatus GN=uppS PE=3 SV=1	351.0	[0..2]	[231..22]
ISPT_GEOKA - Isoprenyl transferase OS=Geobacillus kaustophilus (strain HTA426) GN=uppS PE=3 SV=1 UPPS_GEOKA - Undecaprenyl pyrophosphate synthase OS=Geobacillus kaustophilus GN=uppS PE=3 SV=1	350.0	[0..2]	[233..25]

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Predicted Domain #1

Region A:
Residues: [1-237]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIPRHVAIVM DGNGRWANRR GLPRVAGHRA GAKVVRRIVE YAAEKPLEVL TLFAFSIENR  60
   61 ARPQSEVNFL MSLFLDSLKK NTEELHKNNV QLRVIGDHRE FDKKMLAQIQ TSQDLTKHNT 120
  121 GLKLIIALNY SGRWDILQAV QRMAEKIKNQ ELTSELMSAE LFQNYLCLSD LPEPDLLIRT 180
  181 SGEQRLSNFM LWQFAYTEIY FTPALWPDFN EETFDQALAF YRTRQRRFGL TPEQVEK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	93.522879
Match:	1jp3A
Description:	Undecaprenyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
prenyltransferase activity	4.40397054534951	bayes_pls_golite062009
di-trans,poly-cis-decaprenylcistransferase activity	3.07573514495519	bayes_pls_golite062009
transferase activity	1.42376896518855	bayes_pls_golite062009
catalytic activity	0.878978773660153	bayes_pls_golite062009
dehydrodolichyl diphosphate synthase activity	0.761527128946352	bayes_pls_golite062009
binding	0.747530931796963	bayes_pls_golite062009
protein binding	0.331797220769091	bayes_pls_golite062009
transferase activity, transferring alkyl or aryl (other than methyl) groups	0.256467886977999	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: