YRC Public Data Repository - Protein Structure Prediction

Protein:	DAPB_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	239 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DAPB_COXBU.

Description	E-value	Query Range	Subject Range
DAPB_PSEPK - 4-hydroxy-tetrahydrodipicolinate reductase OS=Pseudomonas putida (strain KT2440) GN=dapB PE=3 SV=1	283.0	[0..2]	[239..1]
DAPB_PSEE4 - 4-hydroxy-tetrahydrodipicolinate reductase OS=Pseudomonas entomophila (strain L48) GN=dapB PE=3 SV=1 gi\|95109001 - gi\|95109001\|emb\|CAK13697.1\| dihydrodipicolinate reductase [Pseudomonas entomophila L48]	282.0	[0..2]	[239..1]
tr\|I7AV70\|I7AV70... - 4-hydroxy-tetrahydrodipicolinate reductase OS=Pseudomonas putida (strain DOT-T1E) GN=dapB PE=3 SV=1 tr\|E4R634\|E4R634... - 4-hydroxy-tetrahydrodipicolinate reductase OS=Pseudomonas putida (strain BIRD-1) GN=dapB PE=3 SV=1 DAPB_PSEP1 - 4-hydroxy-tetrahydrodipicolinate reductase OS=Pseudomonas putida (strain F1 / ATCC 700007) GN=dapB P...	280.0	[0..2]	[239..1]
DAPB_HAES1 - 4-hydroxy-tetrahydrodipicolinate reductase OS=Haemophilus somnus (strain 129Pt) GN=dapB PE=3 SV=1	280.0	[0..1]	[239..1]
DAPB_GEOKA - 4-hydroxy-tetrahydrodipicolinate reductase OS=Geobacillus kaustophilus (strain HTA426) GN=dapB PE=3 ... DAPB_GEOKA - Dihydrodipicolinate reductase OS=Geobacillus kaustophilus GN=dapB PE=3 SV=1	278.0	[0..1]	[239..1]
gi\|227553357, gi... - gi\|227553357\|ref\|ZP_03983406.1\| dihydrodipicolinate reductase [Enterococcus faecalis HH22], gi\|22717... gi\|229545828, gi... - gi\|229545828\|ref\|ZP_04434553.1\| dihydrodipicolinate reductase [Enterococcus faecalis TX1332], gi\|229... DAPB_ENTFA - Dihydrodipicolinate reductase OS=Enterococcus faecalis GN=dapB PE=3 SV=1 gi\|227073800, gi... - gi\|227518747\|ref\|ZP_03948796.1\| dihydrodipicolinate reductase [Enterococcus faecalis TX0104], gi\|227... gi\|229304933, gi... - gi\|229550020\|ref\|ZP_04438745.1\| dihydrodipicolinate reductase [Enterococcus faecalis ATCC 29200], gi... DAPB_ENTFA - 4-hydroxy-tetrahydrodipicolinate reductase OS=Enterococcus faecalis (strain ATCC 700802 / V583) GN=d...	278.0	[0..2]	[239..1]
DAPB_PSEU2 - 4-hydroxy-tetrahydrodipicolinate reductase OS=Pseudomonas syringae pv. syringae (strain B728a) GN=da...	277.0	[0..2]	[239..1]
DAPB_PASMU - 4-hydroxy-tetrahydrodipicolinate reductase OS=Pasteurella multocida (strain Pm70) GN=dapB PE=3 SV=1 DAPB_PASMU - Dihydrodipicolinate reductase OS=Pasteurella multocida GN=dapB PE=3 SV=1	277.0	[0..1]	[239..1]
DAPB_HAEDU - Dihydrodipicolinate reductase OS=Haemophilus ducreyi GN=dapB PE=3 SV=1 DAPB_HAEDU - 4-hydroxy-tetrahydrodipicolinate reductase OS=Haemophilus ducreyi (strain 35000HP / ATCC 700724) GN=...	276.0	[0..2]	[239..1]
gi\|213928510, gi... - gi\|213966660\|ref\|ZP_03394811.1\| dihydrodipicolinate reductase [Pseudomonas syringae pv. tomato T1], ... DAPB_PSESM - Dihydrodipicolinate reductase OS=Pseudomonas syringae pv. tomato GN=dapB PE=3 SV=1 DAPB_PSESM - 4-hydroxy-tetrahydrodipicolinate reductase OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=dap...	276.0	[0..2]	[239..1]

Back

Predicted Domain #1

Region A:
Residues: [1-239]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAINVIINGI NGKMGRVVKE NITAQSDLEL VSGTGRQDDL AKTIQTTHAD VVIDFTTPQS  60
   61 VFHNAEIIIQ SGARPVIGTT GLTLEQIALL DKQCRNKKLG AIVAPNFSVG AVLMMKYAKE 120
  121 AAHYFPDVEI IEMHHSQKID APSGTAIKTA QMIGEMRSSK KDEPFKDRAR GEIKNGIPIH 180
  181 SIRLPGLFSH QSVIFGSNGE TLTIRHDGMD RNCTMPGIFM ACRKVMELDY LVYGLENLL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.221849
Match:	1c3vA
Description:	DIHYDRODIPICOLINATE REDUCTASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND PDC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	2.60548927745815	bayes_pls_golite062009
catalytic activity	2.54843319568228	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	1.54909195188343	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	0.841370849960815	bayes_pls_golite062009
saccharopine dehydrogenase activity	0.495113665163626	bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity	0.0651785123513661	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: