YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30063665, gi\|...
Organism:	Shigella flexneri 2a str. 2457T
Length:	240 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30063665, gi|....

Description	E-value	Query Range	Subject Range
UBIG_ECO8A - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli O8 (strain IAI1) GN=ubiG PE=3 SV=1 UBIG_ECO55 - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli (strain 55989 / EAEC) GN=ubiG PE=3 S... UBIG_SHIBS - Ubiquinone biosynthesis O-methyltransferase OS=Shigella boydii serotype 4 (strain Sb227) GN=ubiG PE=... UBIG_ECOSE - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli (strain SE11) GN=ubiG PE=3 SV=1 UBIG_SHIB3 - Ubiquinone biosynthesis O-methyltransferase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS5... gi\|75238022, gi\|... - gi\|75238022\|ref\|ZP_00722027.1\| COG2227: 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol met...	194.0	[0..1]	[240..1]
gi\|68270929 - gi\|68270929\|gb\|AAY88958.1\| ubiquinone synthesis-related protein [Escherichia coli BL21(DE3)] gi\|68270929\|gb\|A... - ubiquinone synthesis-related protein [Escherichia coli]	194.0	[0..1]	[240..1]
UBIG_ECOLC - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crook... gi\|253772845, gi... - gi\|254289004\|ref\|YP_003054752.1\| 3-demethylubiquinone-9 3-methyltransferase [Escherichia coli BL21(D... gi\|242377867, gi... - gi\|251785594\|ref\|YP_002999898.1\| hypothetical protein B21_02117 [Escherichia coli BL21], gi\|24237786... gi\|253974144, gi... - gi\|254162243\|ref\|YP_003045351.1\| 3-demethylubiquinone-9 3-methyltransferase [Escherichia coli B str.... gi\|124526400, gi... - gi\|124526400\|ref\|ZP_01698353.1\| ubiquinone biosynthesis O-methyltransferase [Escherichia coli B], gi... gi\|188495366, gi... - gi\|75512708\|ref\|ZP_00735210.1\| COG2227: 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol met... gi\|83588218, gi\|... - gi\|83588218\|ref\|ZP_00926843.1\| COG2227: 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol met...	194.0	[0..1]	[240..1]
gi\|189378929, gi... - gi\|189378929\|gb\|EDU97345.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|13362584, gi\|... - gi\|15832369\|ref\|NP_311142.1\| 3-demethylubiquinone-9 3-methyltransferase [Escherichia coli O157:H7 st... gi\|189372803, gi... - gi\|189372803\|gb\|EDU91219.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|189001920, gi... - gi\|189001920\|gb\|EDU70906.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|187771291, gi... - gi\|187771291\|gb\|EDU35135.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|209765554, gi... - pir\|\|E85862 hypothetical protein ubiG [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|208818924, gi... - gi\|208818924\|ref\|ZP_03259244.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:... gi\|208811904, gi... - gi\|208811904\|ref\|ZP_03253233.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:... gi\|254794123, gi... - gi\|254794123\|ref\|YP_003078960.1\| bifunctional 3-demethylubiquinone-9 3-methyltransferase [Escherichi... gi\|208727784, gi... - gi\|208807983\|ref\|ZP_03250320.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:... gi\|12516567, gi\|... - gi\|15802779\|ref\|NP_288806.1\| 3-demethylubiquinone-9 3-methyltransferase [Escherichia coli O157:H7 ED... gi\|195935605 - gi\|195935605\|ref\|ZP_03080987.1\| 3-demethylubiquinone-9 3-methyltransferase [Escherichia coli O157:H7... UBIG_ECO57 - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli O157:H7 GN=ubiG PE=3 SV=1 gi\|189362994, gi... - gi\|189362994\|gb\|EDU81413.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|168761338, gi... - gi\|189368244\|gb\|EDU86660.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|168754977, gi... - gi\|189357734\|gb\|EDU76153.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|168749633, gi... - gi\|188016082\|gb\|EDU54204.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 s... gi\|217327831, gi... - gi\|217327831\|ref\|ZP_03443914.1\| 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:... UBIG_ECO5E - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=ub...	194.0	[0..1]	[240..1]
gi\|115513550, gi... - gi\|117624426\|ref\|YP_853339.1\| 3-demethylubiquinone-9 3-methyltransferase [Escherichia coli APEC O1],...	193.0	[0..1]	[240..17]
EG11143 - bifunctional 3-demethylubiquinone-9 3-methyltransferase / 2-octaprenyl-6-hydroxy phenol methylase / S... EG11143 - bifunctional 3-demethylubiquinone-9 3-methyltransferase / 2-octaprenyl-6-hydroxy phenol methylase / S... UBIG_ECOBW - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=ub... UBIG_ECOLI - 3-demethylubiquinone-9 3-methyltransferase (EC 2.1.1.64) (3,4-dihydroxy-5-hexaprenylbenzoate methylt... UBIG_ECOLU - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) ... UBIG_ECODH - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli (strain K12 / DH10B) GN=ubiG PE=3 SV... gi\|89109049, gi\|... - gi\|89109049\|ref\|AP_002829.1\| bifunctional 3-demethylubiquinone-9 3-methyltransferase and 2-octapreny... UBIG_SHIDS - Ubiquinone biosynthesis O-methyltransferase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=ubi... gi\|193062450, gi... - gi\|75259698\|ref\|ZP_00731000.1\| COG2227: 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol met... gi\|190903451, gi... - gi\|75230378\|ref\|ZP_00716868.1\| COG2227: 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol met... gi\|194427107, gi... - gi\|75211643\|ref\|ZP_00711722.1\| COG2227: 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol met... UBIG_ECO24 - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=...	193.0	[0..1]	[240..1]
gi\|89081582, gi\|... - gi\|89094107\|ref\|ZP_01167050.1\| 3-demethylubiquinone-9 3-methyltransferase [Oceanospirillum sp. MED92...	193.0	[0..1]	[239..1]
gi\|75243047, gi\|... - gi\|75243047\|ref\|ZP_00726753.1\| COG2227: 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol met... UBIG_ECOL5 - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=ub...	192.0	[0..1]	[240..1]
UBIG_ECOUT - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli (strain UTI89 / UPEC) GN=ubiG PE=3 S... UBIG_ECO45 - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=ubiG ... gi\|226901073, gi... - gi\|237704707\|ref\|ZP_04535188.1\| 3-demethylubiquinone-9 3-methyltransferase [Escherichia sp. 3_2_53FA...	192.0	[0..1]	[240..1]
UBIG_ECOHS - Ubiquinone biosynthesis O-methyltransferase OS=Escherichia coli O9:H4 (strain HS) GN=ubiG PE=3 SV=1	192.0	[0..1]	[240..1]

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Predicted Domain #1

Region A:
Residues: [1-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNAEKSPENH NVDHEEIAKF EAVASRWWDL EGEFKPLHRI NPLRLGYIAE RAGGLFGKKV  60
   61 LDVGCGGGIL AESMAREGAT VTGLDMGFEP LQVAKLHALE SGIQVDYVQE TVEEHAAKHA 120
  121 GQYDVVTCME MLEHVPDPQS VVRACAQLVK PGGDVFFSTL NRNGKSWLMA VVGAEYILRM 180
  181 VPKGTHDVKK FIKPAELLGW VDQTSLKERH ITGLHYNPIT NSFKLGPGVD VNYMLHTQNK 240
  241

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.69897
Match:	1kp9A
Description:	CmaA1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.25333584501255	bayes_pls_golite062009
transferase activity	1.07321114919891	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.612108481676679	bayes_pls_golite062009
methyltransferase activity	0.606225212585352	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.14147363365106	bayes_pls_golite062009
binding	0.109975487409217	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: