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View Structure Prediction Details

Protein: FUMC_LEPIC
Organism: Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
Length: 464 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FUMC_LEPIC.

Description E-value Query
Range
Subject
Range
gi|116122205, gi... - gi|116329461|ref|YP_799181.1| fumarate hydratase [Leptospira borgpetersenii serovar Hardjo-bovis L55...
gi|116123624, gi... - gi|116329935|ref|YP_799653.1| fumarate hydratase [Leptospira borgpetersenii serovar Hardjo-bovis JB1...
567.0 [0..1] [464..1]

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Predicted Domain #1
Region A:
Residues: [1-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTRIETDSM GEIAVDDSKY WGAQTERSLH HFHIGNDRFP REMIRALGIL KKSAAVVNAE  60
   61 LGLLSEDKKK LIVQAADEVI SGKLDEHFPL SVWQTGSGTQ TNMNSNEVIS NRAIEIAGGV 120
  121 KGSKKPIHPN DDVNKAQSSN DTFPTAMHIA AAEQLNQKLI PALIQLKETF KKKTDEFQNI 180
  181 IKIGRTHLQD ATPLTLGQEF SGYVQQLEYN IARVKAVLPS VYRLALGGTA VGTGLNTHPQ 240
  241 FAVKAAAQIA KETGLPFVSA ENKFEALAAH DSLVETSGVL KTIAASLMKI ANDIRWLSSG 300
  301 PRCGIGEISI PENEPGSSIM PGKVNPTQSE QMTMVAAQVI ANDVAVNIGG ASGNFELNVF 360
  361 KPLIIHNVLN SIRLLSDSCV SFEEHCARGI IPNKEKLNEH LNNSLMLVTA LNPHIGYDNA 420
  421 AKIAKNAHKK GTTLKESGIE LGLLTSEQFD QWVLPEKMIH PSVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 154.0
Match: 1yfmA
Description: RECOMBINANT YEAST FUMARASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
fumarate hydratase activity 4.22589182982073 bayes_pls_golite062009
catalytic activity 2.51282259572665 bayes_pls_golite062009
lyase activity 2.31268471569846 bayes_pls_golite062009
carbon-nitrogen lyase activity 2.2046475419807 bayes_pls_golite062009
histidine ammonia-lyase activity 0.948129236753279 bayes_pls_golite062009
amidine-lyase activity 0.901614580251298 bayes_pls_golite062009
binding 0.854855116369286 bayes_pls_golite062009
argininosuccinate lyase activity 0.617974375213548 bayes_pls_golite062009
ammonia-lyase activity 0.491229595527877 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle