YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30260764, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	477 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30260764, gi|....

Description	E-value	Query Range	Subject Range
gi\|31580769 - gi\|31580769\|gb\|AAP51177.1\| fumarase [Ascaris suum]	0.0	[1..465]	[1..467]
gi\|50736122, gi\|... - gi\|57530433\|ref\|NP_001006382.1\| fumarate hydratase [Gallus gallus], gi\|53130266\|emb\|CAG31462.1\| hypo...	0.0	[1..464]	[41..506]
l(1)G0255-PB - The gene lethal (1) G0255 is referred to in FlyBase by the symbol Dmel\l(1)G0255 (CG4094, FBgn002833...	0.0	[2..465]	[1..467]
FUMC_PHOLL - Fumarate hydratase class II OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105... FUMC_PHOLL - Fumarate hydratase class II OS=Photorhabdus luminescens subsp. laumondii GN=fumC PE=3 SV=1	0.0	[4..464]	[1..462]
gi\|91084043 - gi\|91084043\|ref\|XP_967085.1\| PREDICTED: similar to AGAP001884-PA [Tribolium castaneum]	0.0	[2..465]	[31..497]
gi\|108875839, gi... - gi\|157118058\|ref\|XP_001658987.1\| aspartate ammonia lyase [Aedes aegypti], gi\|108875839\|gb\|EAT40064.1...	0.0	[7..465]	[42..503]
gi\|49531007, gi\|... - gi\|50085031\|ref\|YP_046541.1\| fumarate hydratase [Acinetobacter sp. ADP1], gi\|49531007\|emb\|CAG68719.1...	0.0	[7..464]	[3..461]
FUMC_LEPIN - Fumarate hydratase class II OS=Leptospira interrogans GN=fumC PE=3 SV=1 FUMC_LEPIC - Fumarate hydratase class II OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhag... FUMC_LEPIN - Fumarate hydratase class II OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (str... FUMC_LEPIC - Fumarate hydratase class II OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhag...	0.0	[6..464]	[2..461]

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Predicted Domain #1

Region A:
Residues: [1-477]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIATKDIRIE KDFLGEKEVP SIAYYGVQTL RAVENFPITG YRIHPSLITA MAIVKKAAAL  60
   61 ANMDTGYLAK DIGHEIAEAA QEIVDGKFHD QFIVDPIQGG AGTSINMNTN EVIANRALER 120
  121 MGYEKGEYAK ISPNTHVNMA QSTNDAFPTG IHIATLMRLE ELLITMEELH AAFRAKAKEF 180
  181 DHVIKMGRTH LQDAVPIRLG QEFEAYSRVL ARDIKRIKQS RQHLYEVNMG ATAVGTGLNA 240
  241 NPTYIEQVVK HLRTFSGFPL VGAEHLVDAT QNTDAYTEVS AALKVCMMNM SKIANDLRIM 300
  301 ASGPRVGLAE IQLPARQPGS SIMPGKVNPV MAEVINQVAF QVIGNDHTIC LASEAGQLEL 360
  361 NVMEPVLVFN LIQSISIMNN GFRVFREYCI KGITANEELL KQYVEKSVGI ITAVNPHIGY 420
  421 EAASRIAREA IETGKSVREL CLEHGVLTEE ELDIILDPFE MTHPEIAGAS LLKDKKM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	138.0
Match:	1j3uA
Description:	L-aspartate ammonia lyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
fumarate hydratase activity	4.22589182982073	bayes_pls_golite062009
catalytic activity	2.51282259572665	bayes_pls_golite062009
lyase activity	2.31268471569846	bayes_pls_golite062009
carbon-nitrogen lyase activity	2.2046475419807	bayes_pls_golite062009
histidine ammonia-lyase activity	0.948129236753279	bayes_pls_golite062009
amidine-lyase activity	0.901614580251298	bayes_pls_golite062009
binding	0.854855116369286	bayes_pls_golite062009
argininosuccinate lyase activity	0.617974375213548	bayes_pls_golite062009
ammonia-lyase activity	0.491229595527877	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: