YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30256075, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	479 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30256075, gi|....

Description	E-value	Query Range	Subject Range
gi\|50736122, gi\|... - gi\|57530433\|ref\|NP_001006382.1\| fumarate hydratase [Gallus gallus], gi\|53130266\|emb\|CAG31462.1\| hypo...	0.0	[5..468]	[41..506]
gi\|31580769 - gi\|31580769\|gb\|AAP51177.1\| fumarase [Ascaris suum]	0.0	[5..468]	[1..466]
gi\|19528365 - gi\|19528365\|gb\|AAL90297.1\| LD46083p [Drosophila melanogaster]	0.0	[3..468]	[26..494]
gi\|157776283 - gi\|157776283\|ref\|XP_001666207.1\| hypothetical protein CBG09180 [Caenorhabditis briggsae AF16] gi\|39582033, gi\|... - gi\|39582033\|emb\|CAE64464.1\| Hypothetical protein CBG09180 [Caenorhabditis briggsae], gi\|187032082\|em...	0.0	[1..468]	[21..490]
gi\|108875839, gi... - gi\|157118058\|ref\|XP_001658987.1\| aspartate ammonia lyase [Aedes aegypti], gi\|108875839\|gb\|EAT40064.1...	0.0	[1..468]	[30..502]
gi\|91769685, gi\|... - gi\|91769685\|ref\|ZP_01271517.1\| Fumarate hydratase, class II [Psychrobacter sp. PRwf-1], gi\|91721172\|...	0.0	[10..468]	[2..461]
gi\|49531007, gi\|... - gi\|50085031\|ref\|YP_046541.1\| fumarate hydratase [Acinetobacter sp. ADP1], gi\|49531007\|emb\|CAG68719.1...	0.0	[11..468]	[3..461]
gi\|42410098, gi\|... - gi\|42520360\|ref\|NP_966275.1\| fumarate hydratase [Wolbachia endosymbiont of Drosophila melanogaster],...	0.0	[7..467]	[1..462]

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Predicted Domain #1

Region A:
Residues: [1-479]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATLTEVKNG VRIEKDFLGE KEVPNYAYYG VQTMRAVENF PITGYKIHEG LIKAFAIVKK  60
   61 AAALANTDVG RLELNKGGAI AEAAQEILDG KWHDHFIVDP IQGGAGTSMN MNANEVIANR 120
  121 ALELLGMEKG DYHYISPNSH VNMAQSTNDA FPTAIHIATL NALEGLLQTM GYMHDVFELK 180
  181 AEQFDHVIKM GRTHLQDAVP IRLGQEFKAY SRVLERDMKR IQQSRQHLYE VNMGATAVGT 240
  241 GLNADPEYIE AVVKHLAAIS ELPLVGAEDL VDATQNTDAY TEVSAALKVC MMNMSKIAND 300
  301 LRLMASGPRV GLAEIMLPAR QPGSSIMPGK VNPVMPEVIN QIAFQVIGND HTICLASEAG 360
  361 QLELNVMEPV LVFNLLQSIS IMNNGFRAFT DNCLKGIEAN EDRLKEYVEK SVGIITAVNP 420
  421 HIGYEAAARV AKEAIATGQS VRELCVKNGV LSQEDLELIL DPFEMTHPGI AGATLLKKN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	137.0
Match:	1j3uA
Description:	L-aspartate ammonia lyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
fumarate hydratase activity	4.22589182982073	bayes_pls_golite062009
catalytic activity	2.51282259572665	bayes_pls_golite062009
lyase activity	2.31268471569846	bayes_pls_golite062009
carbon-nitrogen lyase activity	2.2046475419807	bayes_pls_golite062009
histidine ammonia-lyase activity	0.948129236753279	bayes_pls_golite062009
amidine-lyase activity	0.901614580251298	bayes_pls_golite062009
binding	0.854855116369286	bayes_pls_golite062009
argininosuccinate lyase activity	0.617974375213548	bayes_pls_golite062009
ammonia-lyase activity	0.491229595527877	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: