YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30262593, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	347 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30262593, gi|....

Description	E-value	Query Range	Subject Range
gi\|82702680, gi\|... - gi\|82702680\|ref\|YP_412246.1\| homoserine dehydrogenase [Nitrosospira multiformis ATCC 25196], gi\|8241...	3.0E-97	[1..345]	[14..340]
gi\|66044538, gi\|... - gi\|66044538\|ref\|YP_234379.1\| homoserine dehydrogenase [Pseudomonas syringae pv. syringae B728a], gi\|...	1.0E-96	[3..344]	[33..352]
gi\|254242427, gi... - gi\|254242427\|ref\|ZP_04935749.1\| homoserine dehydrogenase [Pseudomonas aeruginosa 2192], gi\|194553412... gi\|126168577, gi... - gi\|254236646\|ref\|ZP_04929969.1\| homoserine dehydrogenase [Pseudomonas aeruginosa C3719], gi\|19454763... gi\|115586955, gi... - gi\|116051734\|ref\|YP_789427.1\| homoserine dehydrogenase [Pseudomonas aeruginosa UCBPP-PA14], gi\|11558...	2.0E-96	[1..344]	[1..323]
gi\|218889986, gi... - gi\|218889986\|ref\|YP_002438850.1\| homoserine dehydrogenase [Pseudomonas aeruginosa LESB58], gi\|218770... DHOM_PSEAE - Homoserine dehydrogenase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12... DHOM_PSEAE - Homoserine dehydrogenase OS=Pseudomonas aeruginosa GN=hom PE=3 SV=2	2.0E-96	[1..344]	[1..323]
gi\|25283520 - pir\|\|C97023 homoserine dehydrogenase [imported] - Clostridium acetobutylicum gi\|15023906, gi\|... - gi\|15894285\|ref\|NP_347634.1\| homoserine dehydrogenase [Clostridium acetobutylicum ATCC 824], gi\|1502...	4.0E-95	[2..339]	[3..320]
gi\|47014679, gi\|... - gi\|47096969\|ref\|ZP_00234545.1\| homoserine dehydrogenase [Listeria monocytogenes str. 1/2a F6854], gi... gi\|126942388, gi... - gi\|254900314\|ref\|ZP_05260238.1\| homoserine dehydrogenase [Listeria monocytogenes J0161], gi\|15318487... gi\|153180634, gi... - gi\|254937828\|ref\|ZP_05269525.1\| homoserine dehydrogenase [Listeria monocytogenes F6900], gi\|15318063... gi\|153192203, gi... - gi\|254913447\|ref\|ZP_05263459.1\| homoserine dehydrogenase [Listeria monocytogenes J2818], gi\|15319220...	6.0E-95	[2..346]	[4..328]
gi\|71735728, gi\|... - gi\|71735728\|ref\|YP_273618.1\| homoserine dehydrogenase [Pseudomonas syringae pv. phaseolicola 1448A],...	8.0E-95	[1..344]	[1..323]
gi\|52787106, gi\|... - gi\|52787106\|ref\|YP_092935.1\| homoserine dehydrogenase [Bacillus licheniformis ATCC 14580], gi\|523496...	8.0E-95	[1..346]	[1..327]
gi\|16804585 - gi\|16804585\|ref\|NP_466070.1\| homoserine dehydrogenase [Listeria monocytogenes EGD-e] gi\|16412035, gi\|... - pir\|\|AC1393 homoserine dehydrogenase homolog hom [imported] - Listeria monocytogenes (strain EGD-e),... gi\|224503213 - gi\|224503213\|ref\|ZP_03671520.1\| homoserine dehydrogenase [Listeria monocytogenes FSL R2-561] gi\|255025423 - gi\|255025423\|ref\|ZP_05297409.1\| homoserine dehydrogenase [Listeria monocytogenes FSL J2-003]	1.0E-94	[2..346]	[4..328]
gi\|16801752 - gi\|16801752\|ref\|NP_472020.1\| homoserine dehydrogenase [Listeria innocua Clip11262] gi\|16415227, gi\|... - pir\|\|AE1768 homoserine dehydrogenase homolog hom [imported] - Listeria innocua (strain Clip11262), g...	2.0E-94	[2..346]	[4..328]

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Predicted Domain #1

Region A:
Residues: [1-347]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIKVVLSGY GTVGREFIKL LNEKYLYINE TYGIDLVVSG VLGRNVAIHN EDGLSIHHLL  60
   61 RYGGGSCAIE KYIEHHPEER ATDNISGTVL VESTVTNLKD GNPGKQYIKQ AIEKKMDIVA 120
  121 ISKGALVTNW REINEAAKIA NVRIRYSGAT AAALPTLDIG QFSLAGCHIE KIEGILNGTT 180
  181 NYILSKMNEE DIAFEEALKE AQSKGIAETN PILDVSGSDS ACKLLLLTNS LMGTENKLTD 240
  241 IHIKGIEHVT KQQIRNAKEQ NKIIKLIASA YKDNEGNVNL NVEPYKLHKN HPLANVNGTE 300
  301 KGITFFTDTM GQVTTIGGAS NPRVAAAAAL KDIINLYRKD LSRINRE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.39794
Match:	1q7gA
Description:	Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.91887313269429	bayes_pls_golite062009
oxidoreductase activity	2.86254373278283	bayes_pls_golite062009
aspartate-semialdehyde dehydrogenase activity	2.04017093422226	bayes_pls_golite062009
dihydrodipicolinate reductase activity	1.71989205356835	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	1.19591951564949	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1.07932840802619	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.23458869447046	bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity	0.22364954992375	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.22262673350502	bayes_pls_golite062009
glyceraldehyde-3-phosphate dehydrogenase activity	0.0876163188309598	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: