YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30259596, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	464 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30259596, gi|....

Description	E-value	Query Range	Subject Range
gi\|48845511, gi\|... - gi\|78223698\|ref\|YP_385445.1\| anthranilate synthase, component I [Geobacter metallireducens GS-15], g...	0.0	[4..464]	[1..488]
gi\|88936974, gi\|... - gi\|88936974\|ref\|ZP_01142564.1\| Anthranilate synthase component I [Geobacter uraniumreducens Rf4], gi...	0.0	[4..464]	[1..488]
gi\|53765249, gi\|... - gi\|75910917\|ref\|YP_325213.1\| anthranilate synthase, component I [Anabaena variabilis ATCC 29413], gi...	0.0	[4..462]	[1..503]
gi\|17227824, gi\|... - gi\|17227824\|ref\|NP_484372.1\| anthranilate synthase component I [Nostoc sp. PCC 7120], gi\|17129673\|db... gi\|25291358 - pir\|\|AG1847 anthranilate synthetase alpha-chain [imported] - Nostoc sp. (strain PCC 7120)	0.0	[4..462]	[1..503]
gi\|39997478, gi\|... - gi\|39997478\|ref\|NP_953429.1\| anthranilate synthase component I [Geobacter sulfurreducens PCA], gi\|39...	0.0	[4..464]	[1..488]
gi\|186685226, gi... - gi\|23128201\|ref\|ZP_00110054.1\| COG0147: Anthranilate/para-aminobenzoate synthases component I [Nosto...	0.0	[4..462]	[1..508]
gi\|77544427, gi\|... - gi\|77918344\|ref\|YP_356159.1\| anthranilate synthase, component I [Pelobacter carbinolicus DSM 2380], ...	0.0	[4..462]	[1..489]
gi\|95930494, gi\|... - gi\|95930494\|ref\|ZP_01313230.1\| anthranilate synthase component I [Desulfuromonas acetoxidans DSM 684...	0.0	[4..463]	[2..488]
gi\|73660864, gi\|... - gi\|73749148\|ref\|YP_308387.1\| anthranilate synthase component I [Dehalococcoides sp. CBDB1], gi\|73660...	0.0	[4..463]	[1..473]
gi\|70732917, gi\|... - gi\|70732917\|ref\|YP_262688.1\| anthranilate synthase component I [Pseudomonas fluorescens Pf-5], gi\|68...	0.0	[4..464]	[1..489]

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Predicted Domain #1

Region A:
Residues: [1-464]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQTKQIGLQ EVLSAAIKRA TDEKILVSFV KQIDWMDPLL FYAAGKRISF ENRCYFADPA  60
   61 QHVIFAGIGS VFTIATASRK RFQTARDEWD KVKEKAFVQR EKYEFGTGPL LFGGFSFDQE 120
  121 KEKTDLWKEF DDTTFSLPTF LLTVKNEKAW LTMNTFVSAT DCAETLYNEI VSLEEKIFEE 180
  181 SKCALEGSKL TVTSKVEVDP KGWMKAIEKV QDEMKQGNVQ KVVLARELKV EMDHHIDSAL 240
  241 VLEALRIGQP DCYVFSFDYK GACFLGATPE RLIRKEDEKF TSMCLAGSTS HGQSIEESKR 300
  301 NSNALLHDEK NLAEHGYVVN MIRSVLNEHC EFVNIPESPG LLTTKNLIHL YTPVEAKGDA 360
  361 SLLTMVEELH PTPALGGTPR LEAMKLIRDV ELLDRGLYGA PIGWIDDEGN GEFAVALRCG 420
  421 LLNGEKASLF AGCGIVIDSV PQLEYEETSL KFRPMLGALE ELMK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	121.0
Match:	1i1qA
Description:	Anthranilate synthase aminodeoxyisochorismate synthase/lyase subunit, TrpE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.48154800529305	bayes_pls_golite062009
isochorismate synthase activity	2.12058677071834	bayes_pls_golite062009
intramolecular transferase activity, transferring hydroxy groups	2.12058677071834	bayes_pls_golite062009
oxo-acid-lyase activity	1.49234742790531	bayes_pls_golite062009
carbon-carbon lyase activity	1.18272988873809	bayes_pls_golite062009
4-amino-4-deoxychorismate synthase activity	1.13392130624907	bayes_pls_golite062009
anthranilate synthase activity	0.47805305233277	bayes_pls_golite062009
lyase activity	0.151487106592176	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: