YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30255364, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	252 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30255364, gi|....

Description	E-value	Query Range	Subject Range
HIS6_PELTS - Imidazole glycerol phosphate synthase subunit HisF OS=Pelotomaculum thermopropionicum (strain DSM 13...	7.0E-60	[1..252]	[1..252]
HIS6_GEODF - Imidazole glycerol phosphate synthase subunit HisF OS=Geobacter daltonii (strain DSM 22248 / JCM 158...	4.0E-59	[1..252]	[1..253]
HIS6_GEOUR - Imidazole glycerol phosphate synthase subunit HisF OS=Geobacter uraniireducens (strain Rf4) GN=hisF ...	6.0E-59	[1..252]	[1..253]
HIS6_DESHD - Imidazole glycerol phosphate synthase subunit HisF OS=Desulfitobacterium hafniense (strain DCB-2 / D...	6.0E-59	[1..251]	[1..251]
HIS6_DESHY - Imidazole glycerol phosphate synthase subunit HisF OS=Desulfitobacterium hafniense (strain Y51) GN=h...	9.0E-59	[1..251]	[2..252]
HIS6_GEOSL - Imidazole glycerol phosphate synthase subunit HisF OS=Geobacter sulfurreducens (strain ATCC 51573 / ... HIS6_GEOSL - Imidazole glycerol phosphate synthase subunit HisF OS=Geobacter sulfurreducens GN=hisF PE=3 SV=1	4.0E-58	[1..252]	[1..253]
HIS6_THETN - Imidazole glycerol phosphate synthase subunit hisF OS=Thermoanaerobacter tengcongensis GN=hisF PE=3 ... HIS6_CALS4 - Imidazole glycerol phosphate synthase subunit HisF OS=Caldanaerobacter subterraneus subsp. tengconge...	4.0E-58	[1..252]	[1..253]
gi\|118581458, gi... - gi\|71839788\|ref\|ZP_00679530.1\| Histidine biosynthesis protein HisF [Pelobacter propionicus DSM 2379]...	1.0E-57	[1..252]	[1..253]
HIS6_CARHZ - Imidazole glycerol phosphate synthase subunit HisF OS=Carboxydothermus hydrogenoformans (strain ATCC...	2.0E-57	[1..252]	[1..252]
HIS6_AZOBR - Imidazole glycerol phosphate synthase subunit HisF OS=Azospirillum brasilense GN=hisF PE=3 SV=1	2.0E-57	[1..251]	[1..251]

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Predicted Domain #1

Region A:
Residues: [1-252]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAKRIIPCL DVKEGRVVKG VNFIGLQDVG DPVEIAALYN DAGADEIVFL DITATHEGRK  60
   61 TIIDVVEKTA SKVFIPLTVG GGISSVKDMY NLLRAGADKV SINSAAVRNP KLIEEGAQHF 120
  121 GSQCIVVAID ARKVAEGKWN VYVNGGRVDT GMDAIGWAKR VVMLGAGEIL LTSMDADGTK 180
  181 NGYDLRLTEE ISKSVSIPVI ASGGCGHADH IIEVFQKTTV DAALAASIFH YGEATIGDVK 240
  241 RKLRNANVEV RL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.69897
Match:	1ka9F
Description:	Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
imidazoleglycerol-phosphate synthase activity	8.63799159510181	bayes_pls_golite062009
catalytic activity	2.44231061702877	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	1.13340776845419	bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity	0.549444136526559	bayes_pls_golite062009
tryptophan synthase activity	0.426391242491024	bayes_pls_golite062009
lyase activity	0.258652421339738	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: