YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|50122495, gi\|...
Organism:	Pectobacterium atrosepticum SCRI1043
Length:	256 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|50122495, gi|....

Description	E-value	Query Range	Subject Range
gi\|27479658 - gi\|27479658\|gb\|AAO17185.1\| HpaI [Photorhabdus luminescens]	227.0	[0..3]	[256..1]
gi\|52306798, gi\|... - gi\|52424746\|ref\|YP_087883.1\| alpha-dehydro-beta-deoxy-D-glucarate aldolase [Mannheimia succiniciprod...	226.0	[0..7]	[255..7]
gi\|36784398, gi\|... - gi\|37524972\|ref\|NP_928316.1\| 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Photorhabdus luminesce...	221.0	[0..3]	[254..1]
gi\|150841239, gi... - gi\|75428542\|ref\|ZP_00731744.1\| 2-dehydro-3-deoxyglucarate aldolase [Actinobacillus succinogenes 130Z...	221.0	[0..1]	[255..1]
GARL_ECOL6 - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli O6 GN=garL PE=3 SV=1 gi\|227887848, gi... - gi\|227887848\|ref\|ZP_04005653.1\| alpha-dehydro-beta-deoxy-D-glucarate aldolase [Escherichia coli 8397... GARL_ECOL6 - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) G...	220.0	[0..1]	[256..1]
GARL_ECO24 - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=garL PE=... gi\|194427733, gi... - gi\|75211075\|ref\|ZP_00711188.1\| COG3836: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Escherichia... gi\|191166856, gi... - gi\|75229961\|ref\|ZP_00716474.1\| COG3836: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Escherichia... gi\|192959268, gi... - gi\|75239273\|ref\|ZP_00723244.1\| COG3836: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Escherichia... GARL_ECO57 - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli O157:H7 GN=garL PE=3 SV=1 gi\|190907547, gi... - gi\|75240847\|ref\|ZP_00724745.1\| COG3836: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Escherichia... gi\|25324157, gi\|... - pir\|\|D85974 hypothetical protein yhaF [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|193061939, gi... - gi\|75260054\|ref\|ZP_00731332.1\| COG3836: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Escherichia... gi\|12517719, gi\|... - gi\|15803664\|ref\|NP_289697.1\| alpha-dehydro-beta-deoxy-D-glucarate aldolase [Escherichia coli O157:H7... sp\|B7UJ26\|GARL_ECO27 - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=garL PE=... GARL_ECOUT - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli (strain UTI89 / UPEC) GN=garL PE=3 SV=1 gi\|168786004, gi... - gi\|189373881\|gb\|EDU92297.1\| 2-dehydro-3-deoxyglucarate aldolase [Escherichia coli O157:H7 str. EC869... gi\|13363477, gi\|... - gi\|15833258\|ref\|NP_312031.1\| alpha-dehydro-beta-deoxy-D-glucarate aldolase [Escherichia coli O157:H7... gi\|189367588, gi... - gi\|189367588\|gb\|EDU86004.1\| 2-dehydro-3-deoxyglucarate aldolase [Escherichia coli O157:H7 str. EC450... GARL_ECOL5 - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=garL PE=3 ... GARL_ECO27 - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=garL PE=... GARL_ECOSE - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli (strain SE11) GN=garL PE=3 SV=1 GARL_ECOSM - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=garL PE=3 SV=1 GARL_ECOK1 - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli O1:K1 / APEC GN=garL PE=3 SV=1 GARL_SHIBS - 5-keto-4-deoxy-D-glucarate aldolase OS=Shigella boydii serotype 4 (strain Sb227) GN=garL PE=3 SV=1 GARL_ECO8A - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli O8 (strain IAI1) GN=garL PE=3 SV=1 gi\|217327120, gi... - gi\|217327120\|ref\|ZP_03443203.1\| 2-dehydro-3-deoxyglucarate aldolase [Escherichia coli O157:H7 str. T... GARL_ECO55 - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli (strain 55989 / EAEC) GN=garL PE=3 SV=1 GARL_ECO45 - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=garL PE=3 SV=... GARL_ECOLU - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=garL ... GARL_ECO7I - 5-keto-4-deoxy-D-glucarate aldolase OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=garL PE=3 SV... gi\|226899160, gi... - gi\|237706120\|ref\|ZP_04536601.1\| alpha-dehydro-beta-deoxy-D-glucarate aldolase [Escherichia sp. 3_2_5...	220.0	[0..1]	[256..1]
GARL_SHISS - 5-keto-4-deoxy-D-glucarate aldolase OS=Shigella sonnei (strain Ss046) GN=garL PE=3 SV=1	219.0	[0..1]	[256..1]
EG14083 - 2-keto-3-deoxy-L-rhamnonate aldolase / 2-keto-3-deoxy-L-rhamnonate aldolase EG14083 - 2-keto-3-deoxy-L-rhamnonate aldolase / 2-keto-3-deoxy-L-rhamnonate aldolase gi\|253974157, gi... - gi\|254162256\|ref\|YP_003045364.1\| predicted 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Escheric... YFAU_ECOLI - Hypothetical protein yfaU - Escherichia coli gi\|75512721, gi\|... - gi\|75512721\|ref\|ZP_00735223.1\| COG3836: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Escherichia... gi\|124501885, gi... - gi\|124526414\|ref\|ZP_01698367.1\| 2-dehydro-3-deoxyglucarate aldolase [Escherichia coli B], gi\|1245018... gi\|254289017, gi... - gi\|254289017\|ref\|YP_003054765.1\| predicted 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Escheric... gi\|89109062, gi\|... - gi\|89109062\|ref\|AP_002842.1\| predicted 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Escherichia ... gi\|251785606, gi... - gi\|251785606\|ref\|YP_002999910.1\| hypothetical protein B21_02130 [Escherichia coli BL21], gi\|24237787... RHMA_ECOBW - 2-keto-3-deoxy-L-rhamnonate aldolase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=rhmA PE=3... RHMA_ECOLC - 2-keto-3-deoxy-L-rhamnonate aldolase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=r... gi\|83588231, gi\|... - gi\|83588231\|ref\|ZP_00926856.1\| COG3836: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Escherichia... RHMA_ECODH - 2-keto-3-deoxy-L-rhamnonate aldolase OS=Escherichia coli (strain K12 / DH10B) GN=rhmA PE=3 SV=1 RHMA_ECOHS - 2-keto-3-deoxy-L-rhamnonate aldolase OS=Escherichia coli O9:H4 (strain HS) GN=rhmA PE=3 SV=1	219.0	[0..5]	[255..4]
gi\|10120732, gi\|... - gi\|10120733\|pdb\|1DXF\|B Chain B, 2-Dehydro-3-Deoxy-Galactarate Aldolase From Escherichia Coli In Comp...	219.0	[0..1]	[256..1]

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Predicted Domain #1

Region A:
Residues: [1-256]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTPLLPNRF RQDLQQGKTL IGCWCALGNP ISTEVLGLAG FDWLVLDGEH APNDIVTFIP  60
   61 QLMALKGSHS APVVRPPCNE PIIIKRLLDI GFNNFLIPFV ETAEEAARAV ASTRYPPAGI 120
  121 RGVSVAHRSN SYGTEPDYFA KINDNITVVV QIESQDGLDN LDAIIAVDGV DGVFVGPSDL 180
  181 SAALGYLGQP NHPDVQKAIR HIFDRAAAHN KPCGILAPVE ADARRYLEWG ASFVAVGSDL 240
  241 GVFRSATQAL SDKYKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.0
Match:	1dxeA
Description:	2-dehydro-3-deoxy-galactarate aldolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.59838799615646	bayes_pls_golite062009
oxo-acid-lyase activity	0.920775369999745	bayes_pls_golite062009
carbon-carbon lyase activity	0.5165407619773	bayes_pls_golite062009
2-dehydro-3-deoxyglucarate aldolase activity	0.476503494662165	bayes_pls_golite062009
binding	0.415920162243587	bayes_pls_golite062009
transferase activity	0.368032846714701	bayes_pls_golite062009
lyase activity	0.0456521871650777	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: