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View Structure Prediction Details

Protein: gi|50904080, gi|...
Organism: Streptococcus pyogenes MGAS10394
Length: 257 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|50904080, gi|....

Description E-value Query
Range
Subject
Range
gi|94548650, gi|... - gi|94995142|ref|YP_603240.1| 23S rRNA Gm2251 methyltransferase [Streptococcus pyogenes MGAS10750], g...
gi|71904302, gi|... - gi|71904302|ref|YP_281105.1| 23S rRNA methyltransferase [Streptococcus pyogenes MGAS6180], gi|718033...
gi|94991229, gi|... - gi|94991229|ref|YP_599329.1| 23S rRNA Gm2251 methyltransferase [Streptococcus pyogenes MGAS10270], g...
283.0 [0..1] [257..1]

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Predicted Domain #1
Region A:
Residues: [1-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKHSWYNKLM EDKDTIETND IVYGVHAVTE SLQANTGNKL YIQEDLRGKK VDNIKSLATQ  60
   61 KKVAISWTPK KTLSQMTDGA VHQGFVLRVS AFAYTDVDEI LEIAEQEANP LILILDGLTD 120
  121 PHNLGSILRT ADATNVCGVI IPKHRSVGVT PVVSKTSTGA VEHIPIARVT NLSQILDKLK 180
  181 ARGFWIFGTD MNGTPSDCWN TNGKLALVIG NEGKGISTNI KKQVDEMITI PMNGHVQSLN 240
  241 ASVAAAILMY EVFRNRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.0
Match: 1gz0A
Description: RlmB, C-terminal domain; RlmB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA methyltransferase activity 4.23455016472464 bayes_pls_golite062009
methyltransferase activity 3.59960278169345 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 3.51722801996622 bayes_pls_golite062009
rRNA methyltransferase activity 3.14976989427746 bayes_pls_golite062009
tRNA methyltransferase activity 2.33123191403389 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 2.23755555119187 bayes_pls_golite062009
tRNA (guanine) methyltransferase activity 2.14623472760939 bayes_pls_golite062009
transferase activity 1.63934797352054 bayes_pls_golite062009
structural constituent of ribosome 1.0137045454994 bayes_pls_golite062009
catalytic activity 0.797300463760338 bayes_pls_golite062009
N-methyltransferase activity 0.736216022000293 bayes_pls_golite062009
structural molecule activity 0.694233763389628 bayes_pls_golite062009
binding 0.650146274744039 bayes_pls_golite062009
nucleic acid binding 0.404179021204849 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 0.319046095835882 bayes_pls_golite062009
0.16936231012632 bayes_pls_golite062009
snoRNA binding 0.155192244522672 bayes_pls_golite062009
protein binding 0.031057919963412 bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity 6.26422903788337E-4 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle