YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|11351140
Organism:	Pseudomonas aeruginosa
Length:	242 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|11351140.

Description	E-value	Query Range	Subject Range
gi\|126169587, gi... - gi\|254237656\|ref\|ZP_04930979.1\| hypothetical protein PACG_03741 [Pseudomonas aeruginosa C3719], gi\|1... gi\|115589044, gi... - gi\|116053823\|ref\|YP_788260.1\| carbonic anhydrase [Pseudomonas aeruginosa UCBPP-PA14], gi\|115589044\|g... gi\|254243209, gi... - gi\|254243209\|ref\|ZP_04936531.1\| hypothetical protein PA2G_04014 [Pseudomonas aeruginosa 2192], gi\|19... gi\|218769070, gi... - gi\|218888847\|ref\|YP_002437711.1\| putative carbonic anhydrase [Pseudomonas aeruginosa LESB58], gi\|218...	1.0E-78	[1..242]	[1..242]
gi\|49082084 - gi\|49082084\|gb\|AAT50442.1\| PA0102 [synthetic construct]	1.0E-78	[1..242]	[1..242]
gi\|94416100 - gi\|94416100\|ref\|ZP_01295931.1\| hypothetical protein PaerP_01002180 [Pseudomonas aeruginosa PA7]	8.0E-77	[5..241]	[1..237]
gi\|67155659 - gi\|67155659\|ref\|ZP_00417286.1\| Carbonate dehydratase [Azotobacter vinelandii AvOP] gi\|67086603, gi\|... - gi\|67155659\|ref\|ZP_00417286.1\| Carbonate dehydratase [Azotobacter vinelandii AvOP], gi\|67086603\|gb\|E...	2.0E-71	[3..239]	[104..340]
gi\|77456310, gi\|... - gi\|77456310\|ref\|YP_345815.1\| carbonic anhydrase [Pseudomonas fluorescens Pf0-1], gi\|77380313\|gb\|ABA7...	3.0E-71	[17..239]	[21..243]
gi\|68347870, gi\|... - gi\|70733571\|ref\|YP_257210.1\| carbonic anhydrase [Pseudomonas fluorescens Pf-5], gi\|68347870\|gb\|AAY95...	5.0E-71	[5..239]	[2..236]
gi\|24981444, gi\|... - gi\|26986845\|ref\|NP_742270.1\| carbonate dehydratase [Pseudomonas putida KT2440], gi\|24981444\|gb\|AAN65... tr\|I7B631\|I7B631... - Carbonic anhydrase OS=Pseudomonas putida (strain DOT-T1E) GN=cynT PE=3 SV=1 tr\|E4R9R9\|E4R9R9... - Carbonic anhydrase OS=Pseudomonas putida (strain BIRD-1) GN=cynT PE=3 SV=1 gi\|148545372, gi... - gi\|82737367\|ref\|ZP_00900217.1\| carbonic anhydrase [Pseudomonas putida F1], gi\|82715531\|gb\|EAP50595.1...	8.0E-70	[1..239]	[1..239]
gi\|66043558, gi\|... - gi\|66043558\|ref\|YP_233399.1\| carbonate dehydratase [Pseudomonas syringae pv. syringae B728a], gi\|632...	5.0E-69	[21..239]	[25..243]
tr\|Q87UP1\|Q87UP1... - Carbonic anhydrase OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=cynT PE=3 SV=1 gi\|28855622, gi\|... - gi\|28872367\|ref\|NP_794986.1\| carbonic anhydrase [Pseudomonas syringae pv. tomato str. DC3000], gi\|28...	1.0E-68	[22..239]	[1..218]
gi\|95108353 - gi\|95108353\|emb\|CAK13047.1\| carbonic anhydrase [Pseudomonas entomophila L48] gi\|95108353, gi\|... - gi\|95108353\|emb\|CAK13047.1\| carbonic anhydrase [Pseudomonas entomophila L48], gi\|104779366\|ref\|YP_60...	4.0E-68	[22..239]	[22..239]

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Predicted Domain #1

Region A:
Residues: [1-242]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDRMRGVKS DSPEQESADD ALKRIVDGFQ HFRREVFPEQ QALFKKLANS QRPRAMFITC  60
   61 ADSRIVPELI TQSSPGDLFV TRNVGNVVPP YGQMNGGVST AIEYAVLALG VHHIIVCGHS 120
  121 DCGAMRAVLD PQTLERMPTV KAWLRHAEVA RTVVADNCDC GASHDTLGVL TEENVVAQLD 180
  181 HLRTHPSVAS RLASGQLFIH GWVYDIESAQ IRAYDAKQGR FLPLDGEHPV PMATPAPRYL 240
  241 SS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.045757
Match:	1i6oA
Description:	beta-carbonic anhydrase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbonate dehydratase activity	2.96380803089124	bayes_pls_golite062009
catalytic activity	1.85658156053797	bayes_pls_golite062009
carbon-oxygen lyase activity	1.691366175135	bayes_pls_golite062009
hydro-lyase activity	1.65497918079842	bayes_pls_golite062009
lyase activity	1.62374861994341	bayes_pls_golite062009
binding	1.32962036184517	bayes_pls_golite062009
protein binding	0.132818074687599	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: