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View Structure Prediction Details

Protein: gi|13622961, gi|...
Organism: Streptococcus pyogenes M1 GAS
Length: 248 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|13622961, gi|....

Description E-value Query
Range
Subject
Range
gi|94548650, gi|... - gi|94995142|ref|YP_603240.1| 23S rRNA Gm2251 methyltransferase [Streptococcus pyogenes MGAS10750], g...
gi|71904302, gi|... - gi|71904302|ref|YP_281105.1| 23S rRNA methyltransferase [Streptococcus pyogenes MGAS6180], gi|718033...
gi|94991229, gi|... - gi|94991229|ref|YP_599329.1| 23S rRNA Gm2251 methyltransferase [Streptococcus pyogenes MGAS10270], g...
254.0 [0..1] [248..10]

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Predicted Domain #1
Region A:
Residues: [1-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDKDTIETN DIVYGVHAVT ESLQANTGNK LYIQEDLRGK KVDNIKSLAT QKKVAISWTP  60
   61 KKTLSQMTDG AVHQGFVLRV SAFAYTDVDE ILEIAEQEAN PLILILDGLT DPHNLGSILR 120
  121 TADATNVCGV IIPKHRSVGV TPVVSKTSTG AVEHIPIARV TNLSQTLDKL KARGFWIFGT 180
  181 DMNGTPSDCW NTNGKLALVI GNEGKGISTN IKKQVDEMIT IPMNGHVQSL NASVAAAILM 240
  241 YEVFRNRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.30103
Match: 1gz0A
Description: RlmB, C-terminal domain; RlmB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA methyltransferase activity 4.23455016472464 bayes_pls_golite062009
methyltransferase activity 3.59960278169345 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 3.51722801996622 bayes_pls_golite062009
rRNA methyltransferase activity 3.14976989427746 bayes_pls_golite062009
RNA binding 2.61675538965988 bayes_pls_golite062009
tRNA methyltransferase activity 2.33123191403389 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 2.23755555119187 bayes_pls_golite062009
tRNA (guanine) methyltransferase activity 2.14623472760939 bayes_pls_golite062009
nucleic acid binding 1.81000672982144 bayes_pls_golite062009
transferase activity 1.63934797352054 bayes_pls_golite062009
binding 1.31970199852267 bayes_pls_golite062009
structural constituent of ribosome 1.0137045454994 bayes_pls_golite062009
N-methyltransferase activity 0.736216022000293 bayes_pls_golite062009
structural molecule activity 0.694233763389628 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 0.319046095835882 bayes_pls_golite062009
catalytic activity 0.264002643439785 bayes_pls_golite062009
0.16936231012632 bayes_pls_golite062009
snoRNA binding 0.155192244522672 bayes_pls_golite062009
protein binding 0.131685221037103 bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity 6.26422903788337E-4 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle