YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7473983
Organism:	Deinococcus radiodurans
Length:	286 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7473983.

Description	E-value	Query Range	Subject Range
TAL_DEIRA - Probable transaldolase OS=Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4... TAL_DEIRA - Probable transaldolase OS=Deinococcus radiodurans GN=tal PE=3 SV=2	1.0E-79	[53..286]	[1..234]
TAL_AQUAE - Probable transaldolase OS=Aquifex aeolicus (strain VF5) GN=tal PE=3 SV=1 TAL_AQUAE - Probable transaldolase OS=Aquifex aeolicus GN=tal PE=3 SV=1	1.0E-78	[53..268]	[1..215]
gi\|58177039, gi\|... - gi\|58177049\|pdb\|1VPX\|T Chain T, Crystal Structure Of Transaldolase (Ec 2.2.1.2) (Tm0295) From Thermo...	9.0E-77	[53..264]	[13..223]
TAL_THEMA - Transaldolase OS=Thermotoga maritima GN=tal PE=1 SV=1 TAL_THEMA - Transaldolase OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=tal PE=1 S...	1.0E-76	[53..264]	[1..211]
gi\|241884203, gi... - gi\|241903436\|ref\|ZP_04788160.1\| transaldolase [Thermoanaerobacter brockii subsp. finnii Ako-1], gi\|2... gi\|166855877, gi... - gi\|76796335\|ref\|ZP_00778699.1\| Transaldolase C [Thermoanaerobacter ethanolicus ATCC 33223], gi\|76588...	4.0E-76	[53..268]	[2..216]
gi\|242258562, gi... - gi\|242258562\|ref\|ZP_04803344.1\| transaldolase [Thermoanaerobacter sp. X513], gi\|242229917\|gb\|EES3234... gi\|255253001, gi... - gi\|255253001\|ref\|ZP_05332581.1\| transaldolase [Thermoanaerobacter italicus Ab9], gi\|255115356\|gb\|EET... TAL_THEPX - Probable transaldolase OS=Thermoanaerobacter sp. (strain X514) GN=tal PE=3 SV=1	7.0E-76	[53..268]	[1..215]
TAL_METMP - Probable transaldolase OS=Methanococcus maripaludis (strain S2 / LL) GN=tal PE=3 SV=1 TAL_METMP - Probable transaldolase OS=Methanococcus maripaludis GN=tal PE=3 SV=1	8.0E-76	[53..264]	[1..211]
TAL_METJA - Probable transaldolase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM ... TAL_METJA - Probable transaldolase OS=Methanocaldococcus jannaschii GN=tal PE=3 SV=1	8.0E-76	[53..262]	[1..209]
TAL_THETN - Probable transaldolase OS=Thermoanaerobacter tengcongensis GN=tal PE=3 SV=1 gi\|223489182, gi... - gi\|254479019\|ref\|ZP_05092376.1\| transaldolase, putative [Carboxydibrachium pacificum DSM 12653], gi\|... TAL_CALS4 - Probable transaldolase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM...	4.0E-75	[53..268]	[1..215]
TAL_GEOUR - Probable transaldolase OS=Geobacter uraniireducens (strain Rf4) GN=tal PE=3 SV=1	5.0E-75	[53..265]	[1..212]

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Predicted Domain #1

Region A:
Residues: [1-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGWPEGRAPV APEQGAPGPF FSDRGGVCWR HPAQVRQGKS GAGPAVPLRR THMEFFIDTA  60
   61 IVDEIREINA WGVLSGVTTN PSLIVASGRD FKEVIGEIAE LVPGGAISAE VTALDAEGMI 120
  121 KEGKDVAAWH KQVVVKLPLT PAGLQACKAL TSEGIKTNVT LCFSVPQALL AARAGATYVS 180
  181 PFVGRVDDTG WDGSELIRQI KEAFVLGDIQ TKVLAASIRH PQHVVQAALA GADVATIPYK 240
  241 VFTQMVKHPL TQAGLDSFMA DWAKRQGASP ETPPSEAGTN PVKKEG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	78.30103
Match:	1vpxA
Description:	Crystal structure of Transaldolase (EC 2.2.1.2) (TM0295) from Thermotoga maritima at 2.40 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring aldehyde or ketonic groups	3.28746773527289	bayes_pls_golite062009
transaldolase activity	2.77878684721788	bayes_pls_golite062009
catalytic activity	2.67031204377352	bayes_pls_golite062009
fructose-bisphosphate aldolase activity	1.41110985630781	bayes_pls_golite062009
porphobilinogen synthase activity	0.658378297259497	bayes_pls_golite062009
fructose binding	0.427637212154492	bayes_pls_golite062009
aldehyde-lyase activity	0.351872954170322	bayes_pls_golite062009
transferase activity, transferring alkyl or aryl (other than methyl) groups	0.0319140634878892	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: