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View Structure Prediction Details

Protein: SIFR-PC, SIFR-PA
Organism: Drosophila melanogaster
Length: 758 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIFR-PC, SIFR-PA.

Description E-value Query
Range
Subject
Range
SIFR-PB - The gene SIFamide receptor is referred to in FlyBase by the symbol Dmel\SIFR (CG10823, FBgn0038880)....
341.0 [0..1] [519..1]

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Predicted Domain #1
Region A:
Residues: [1-174]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMAASGRIRK RKHKSHTSGD VPSTTTSVPM PIPTMAPGKM VAETMEEAAA LAGDYNNFTH  60
   61 NFVDLQNLLS FNELNGTSGS GGTAVSSLGS SSAIKLNNSA ITDTLLGTVL TTATATVAPA 120
  121 ASSLLATLAA TTTASARGSL AGKSLAIADA TSSTYYSNLL NLSPATTSLI SAAA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.0
Match: 1xwdC
Description: Crystal Structure of Human Follicle Stimulating Hormone Complexed with its Receptor
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [175-562]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATKSYNDSAL RWEQLDGSVD FGFDPLYRHS LAMSMVYCVA YIVVFLVGLI GNSFVIAVVL  60
   61 RAPRMRTVTN YFIVNLAIAD ILVIVFCLPA TLIGNIFVPW MLGWLMCKFV PYIQGVSVAA 120
  121 SVYSLIAVSL DRFIAIWWPL KQMTKRRARI MIIGIWVIAL VTTIPWLLFF DLVPAEEVFS 180
  181 DALVSAYSQP QFLCQEVWPP GTDGNLYFLL ANLVACYLLP MSLITLCYVL IWIKVSTRSI 240
  241 PGESKDAQMD RMQQKSKVKV IKMLVAVVIL FVLSWLPLYV IFARIKFGSD ISQEEFEILK 300
  301 KVMPVAQWLG SSNSCINPIL YSVNKKYRRG FAAIIKSRSC CGRLRYYDNV AIASSTTSTR 360
  361 KSSHYHQNSS RKSPSSKGNA VSYIYEHN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.522879
Match: 1f88A
Description: Rhodopsin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [563-758]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLRRHNMMLK QDSNLSQQML LKQDSHGSRQ FLIKQESSCS DASGIRRPLC QQDSNGSKVS  60
   61 LSKQDSIVSY MEARRSAGHG LNDTLVDRDS VSMDVGRRQG ATPSSLLDKR QKFVKQDSVI 120
  121 SFVDQRPEQR RHQLVKQDSV ISFADQRRGL LHKQDSLMAN RTGDAPTHHV SILKKTDSQL 180
  181 SYGSSTSPRR NADLYE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle