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View Structure Prediction Details

Protein: sdt-PF
Organism: Drosophila melanogaster
Length: 859 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sdt-PF.

Description E-value Query
Range
Subject
Range
sdt-PH - The gene stardust is referred to in FlyBase by the symbol Dmel\sdt (CG32717, FBgn0243505). It is a p...
604.0 [0..1] [859..76]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTMLSVNQD NGPHREMAVD CPDTFIARNK TPPRYPPPRP PQLNGNAKPV PPPRDHLRVE  60
   61 KDGRLVNCSP APQLPDRRAP GNASSGSSGA TTHPLQHQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [99-253]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QIAQIVEPTL EQLDSIKKYQ EQLRRRREEE ERIAQQNEFL RNSLRGSRKL KALQDTATPG  60
   61 KAVAQQQQQA TLATQVVGVE NEAYLPDEDQ PQAEQIDGYG ELIAALTRLQ NQLSKSGLST 120
  121 LAGRVSAAHS VLASASVAHV LAARTAVLQR RRSRV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [254-366]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGPLHHSSLG LQKDIVELLT QSNTAAAIEL GNLLTSHEME GLLLAHDRIA NHTDGTPSPT  60
   61 PTPTPAIGAA TGSTLSSPVA GPKRNLGMVV PPPVVPPPLA QRGAMPLPRG ESP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.37
Match: 1zl8B
Description: NMR structure of L27 heterodimer from C. elegans Lin-7 and H. sapiens Lin-2 scaffold proteins
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [367-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPVPMPPLAT MPMSMPVNLP MSACFGTLND QNDNIRIIQI EKSTEPLGAT VRNEGEAVVI  60
   61 GRIVRGGAAE KSGLLHEGDE ILEVNGQELR GKTVNEVCAL LGAMQGTLTF LIVPAGSPPS 120
  121 VGVMGGTTGS Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.522879
Match: 1va8A
Description: Solution structure of the PDZ domain of Pals1 protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.2595117613307 bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity 3.03529700765506 bayes_pls_golite062009
substrate-specific transporter activity 2.83180079733297 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.39826531242265 bayes_pls_golite062009
protein binding 2.35875654816667 bayes_pls_golite062009
nucleotide kinase activity 1.79696347300128 bayes_pls_golite062009
guanylate kinase activity 1.70730560221787 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 1.69528181005421 bayes_pls_golite062009
cytoskeletal protein binding 1.68920668586004 bayes_pls_golite062009
signal transducer activity 1.51162321843898 bayes_pls_golite062009
molecular transducer activity 1.51162321843898 bayes_pls_golite062009
protein domain specific binding 0.64214865642772 bayes_pls_golite062009
transcription regulator activity 0.387065538161985 bayes_pls_golite062009
receptor binding 0.359972518335054 bayes_pls_golite062009
actin binding 0.13059495339034 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [498-859]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAGLGGAHRD TAVLHVRAHF DYDPEDDLYI PCRELGISFQ KGDVLHVISR EDPNWWQAYR  60
   61 EGEEDQTLAG LIPSQSFQHQ RETMKLAIAE EAGLARSRGK DGSGSKGATL LCARKGRKKK 120
  121 KKASSEAGYP LYATTAPDET DPEEILTYEE VALYYPRATH KRPIVLIGPP NIGRHELRQR 180
  181 LMADSERFSA AVPHTSRARR EGEVPGVDYH FITRQAFEAD ILARRFVEHG EYEKAYYGTS 240
  241 LEAIRTVVAS GKICVLNLHP QSLKLLRASD LKPYVVLVAP PSLDKLRQKK LRNGEPFKEE 300
  301 ELKDIIATAR DMEARWGHLF DMIIINNDTE RAYHQLLAEI NSLEREPQWV PAQWVHNNRD 360
  361 ES

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.154902
Match: 1kjwA
Description: Psd-95; Guanylate kinase-like domain of Psd-95
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle