YRC Public Data Repository - Protein Structure Prediction

Protein:	PYRE_ACIAD
Organism:	Acinetobacter sp. ADP1
Length:	237 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PYRE_ACIAD.

Description	E-value	Query Range	Subject Range
gi\|229356093, gi... - gi\|229506988\|ref\|ZP_04396496.1\| orotate phosphoribosyltransferase [Vibrio cholerae BX 330286], gi\|22... gi\|229512475, gi... - gi\|229512475\|ref\|ZP_04401947.1\| orotate phosphoribosyltransferase [Vibrio cholerae TMA 21], gi\|22935... gi\|229516305, gi... - gi\|229516305\|ref\|ZP_04405753.1\| orotate phosphoribosyltransferase [Vibrio cholerae RC9], gi\|22934673... gi\|229369151, gi... - gi\|229606496\|ref\|YP_002877144.1\| orotate phosphoribosyltransferase [Vibrio cholerae MJ-1236], gi\|229... gi\|124118745, gi... - gi\|153222605\|ref\|ZP_01953309.1\| orotate phosphoribosyltransferase [Vibrio cholerae MAK 757], gi\|1241... gi\|75830214, gi\|... - gi\|75830214\|ref\|ZP_00759496.1\| COG0461: Orotate phosphoribosyltransferase [Vibrio cholerae MO10], gi... gi\|126509508, gi... - gi\|153819944\|ref\|ZP_01972611.1\| orotate phosphoribosyltransferase [Vibrio cholerae NCTC 8457], gi\|12... gi\|229509358, gi... - gi\|229509358\|ref\|ZP_04398841.1\| orotate phosphoribosyltransferase [Vibrio cholerae B33], gi\|22935367... PYRE_VIBCH - (Q9KVD5) Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRT) (OPRTase) gi\|9654618, gi\|1... - gi\|9654618\|gb\|AAF93387.1\| orotate phosphoribosyltransferase [Vibrio cholerae O1 biovar El Tor str. N... gi\|150422455, gi... - gi\|254291598\|ref\|ZP_04962387.1\| orotate phosphoribosyltransferase [Vibrio cholerae AM-19226], gi\|197... gi\|227080432, gi... - gi\|227080432\|ref\|YP_002808983.1\| orotate phosphoribosyltransferase [Vibrio cholerae M66-2], gi\|22700...	178.0	[0..29]	[237..5]

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Predicted Domain #1

Region A:
Residues: [1-237]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSYPLVSCA SLTSIDESGA PMTTPSSFNP QAFIELALSR GVLKFGEFTL KSGRVSPYFF  60
   61 NAGLLNDGEA LSLLAQGYAD QLMQCQHVDV IFGPAYKGIP FVAATAVALS QLHAKSVPWG 120
  121 FNRKEAKDHG EGGVLVGASV EGKKVWIIDD VITAGTAIRE VVTILKNAGA TIAGVLVALD 180
  181 RQERGQGQLS AIQEVQQELE IPVHALITMK DLMNYLDAKG ETQALAKMED YRLKYGI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.30103
Match:	1oroA
Description:	Orotate PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
adenine phosphoribosyltransferase activity	3.1748712918814	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	3.0470646511978	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	2.97347277288245	bayes_pls_golite062009
transferase activity	2.73727660668741	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.21367942706564	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	2.02298774328915	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.51875493459374	bayes_pls_golite062009
nucleobase binding	1.28671115202467	bayes_pls_golite062009
purine binding	1.24786927434743	bayes_pls_golite062009
amidophosphoribosyltransferase activity	0.932396739123353	bayes_pls_golite062009
binding	0.847513071499147	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
nucleic acid binding	0.552133387792911	bayes_pls_golite062009
DNA binding	0.439741935655503	bayes_pls_golite062009
transcription regulator activity	0.396538943915776	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: