YRC Public Data Repository - Protein Structure Prediction

Protein:	tr\|J6CVB7\|J6CVB7...
Organism:	SPECIES UNKNOWN
Length:	135 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tr|J6CVB7|J6CVB7....

Description	E-value	Query Range	Subject Range
gi\|150841188, gi... - gi\|75431428\|ref\|ZP_00733000.1\| Lactoylglutathione lyase [Actinobacillus succinogenes 130Z], gi\|74276...	139.0	[0..1]	[135..1]
gi\|32029379, gi\|... - gi\|32029379\|ref\|ZP_00132412.1\| COG0346: Lactoylglutathione lyase and related lyases [Haemophilus som... gi\|113460647, gi... - gi\|113460647\|ref\|YP_718713.1\| lactoylglutathione lyase (glyoxalase I) [Haemophilus somnus 129PT], gi...	138.0	[0..1]	[135..1]
gi\|227081184, gi... - gi\|227081184\|ref\|YP_002809735.1\| lactoylglutathione lyase [Vibrio cholerae M66-2], gi\|227009072\|gb\|A... gi\|153829533, gi... - gi\|153829533\|ref\|ZP_01982200.1\| lactoylglutathione lyase [Vibrio cholerae 623-39], gi\|148874993\|gb\|E... gi\|229350904, gi... - gi\|229510939\|ref\|ZP_04400418.1\| lactoylglutathione lyase [Vibrio cholerae B33], gi\|229350904\|gb\|EEO1... gi\|229515396, gi... - gi\|229515396\|ref\|ZP_04404855.1\| lactoylglutathione lyase [Vibrio cholerae TMA 21], gi\|229347165\|gb\|E... gi\|9655474, gi\|1... - gi\|9655474\|gb\|AAF94171.1\| lactoylglutathione lyase [Vibrio cholerae O1 biovar El Tor str. N16961], g... gi\|227012827, gi... - gi\|227117377\|ref\|YP_002819273.1\| lactoylglutathione lyase [Vibrio cholerae O395], gi\|227012827\|gb\|AC... gi\|229357614, gi... - gi\|229505391\|ref\|ZP_04394901.1\| lactoylglutathione lyase [Vibrio cholerae BX 330286], gi\|229357614\|g... gi\|254843845, gi... - gi\|254848140\|ref\|ZP_05237490.1\| lactoylglutathione lyase [Vibrio cholerae MO10], gi\|254843845\|gb\|EET... gi\|229344775, gi... - gi\|229518060\|ref\|ZP_04407504.1\| lactoylglutathione lyase [Vibrio cholerae RC9], gi\|229344775\|gb\|EEO0... gi\|121628268, gi... - gi\|121729982\|ref\|ZP_01682399.1\| lactoylglutathione lyase [Vibrio cholerae V52], gi\|121628268\|gb\|EAX6... gi\|229371065, gi... - gi\|229608410\|ref\|YP_002879058.1\| lactoylglutathione lyase [Vibrio cholerae MJ-1236], gi\|229371065\|gb... LGUL_VIBCH - (Q9KT93) Probable lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase) (Aldoketomutase) (Glyoxal...	137.0	[0..2]	[133..51]
gi\|52306810, gi\|... - gi\|52424758\|ref\|YP_087895.1\| GloA protein [Mannheimia succiniciproducens MBEL55E], gi\|52306810\|gb\|AA...	137.0	[0..1]	[135..2]
gi\|45441959, gi\|... - gi\|45441959\|ref\|NP_993498.1\| lactoylglutathione lyase [Yersinia pestis biovar Microtus str. 91001], ... gi\|22125849, gi\|... - gi\|22125849\|ref\|NP_669272.1\| lactoylglutathione lyase [Yersinia pestis KIM], gi\|21958780\|gb\|AAM85523...	136.0	[0..1]	[135..14]
gi\|71669193, gi\|... - gi\|71677562\|ref\|ZP_00675298.1\| Glyoxalase I [Trichodesmium erythraeum IMS101], gi\|71669193\|gb\|EAO258...	135.0	[0..1]	[133..1]
gi\|186895674, gi... - gi\|186895674\|ref\|YP_001872786.1\| lactoylglutathione lyase [Yersinia pseudotuberculosis PB1/+], gi\|18... gi\|117673408, gi... - gi\|77629366\|ref\|ZP_00791952.1\| COG0346: Lactoylglutathione lyase and related lyases [Yersinia pseudo... gi\|51589901, gi\|... - gi\|51596619\|ref\|YP_070810.1\| lactoylglutathione lyase [Yersinia pseudotuberculosis IP 32953], gi\|515... gi\|170024108, gi... - gi\|170024108\|ref\|YP_001720613.1\| lactoylglutathione lyase [Yersinia pseudotuberculosis YPIII], gi\|16... Q66A37\|Q66A37_YERPS - Lactoylglutathione lyase - Yersinia pseudotuberculosis	135.0	[0..1]	[135..1]
gi\|53763628, gi\|... - gi\|75906364\|ref\|YP_320660.1\| glyoxalase I [Anabaena variabilis ATCC 29413], gi\|75700089\|gb\|ABA19765....	135.0	[0..1]	[125..1]
gi\|108807722, gi... - gi\|108807722\|ref\|YP_651638.1\| lactoylglutathione lyase [Yersinia pestis Antiqua], gi\|108779635\|gb\|AB... gi\|229680643, gi... - gi\|229902308\|ref\|ZP_04517428.1\| glyoxalase I, Ni-dependent [Yersinia pestis Nepal516], gi\|229680643\|... gi\|165921726, gi... - gi\|165926505\|ref\|ZP_02222337.1\| lactoylglutathione lyase [Yersinia pestis biovar Orientalis str. F19... gi\|166010704, gi... - gi\|166010704\|ref\|ZP_02231602.1\| lactoylglutathione lyase [Yersinia pestis biovar Antiqua str. E19790... gi\|166210885, gi... - gi\|166210885\|ref\|ZP_02236920.1\| lactoylglutathione lyase [Yersinia pestis biovar Antiqua str. B42003... gi\|167049656, gi... - gi\|167400803\|ref\|ZP_02306309.1\| lactoylglutathione lyase [Yersinia pestis biovar Antiqua str. UG05-0... gi\|167422140, gi... - gi\|167422140\|ref\|ZP_02313893.1\| lactoylglutathione lyase [Yersinia pestis biovar Orientalis str. MG0... gi\|165938651, gi... - gi\|89103794\|ref\|ZP_01176358.1\| COG0346: Lactoylglutathione lyase and related lyases [Yersinia pestis... gi\|167424835, gi... - gi\|167424835\|ref\|ZP_02316588.1\| lactoylglutathione lyase [Yersinia pestis biovar Mediaevalis str. K1... gi\|229688512, gi... - gi\|229898468\|ref\|ZP_04513614.1\| glyoxalase I, Ni-dependent [Yersinia pestis biovar Orientalis str. I... gi\|229701954, gi... - gi\|229895066\|ref\|ZP_04510243.1\| glyoxalase I, Ni-dependent [Yersinia pestis Pestoides A], gi\|2297019... gi\|229837905, gi... - gi\|229837905\|ref\|ZP_04458064.1\| glyoxalase I, Ni-dependent [Yersinia pestis biovar Orientalis str. P... gi\|162353136, gi... - gi\|77633722\|ref\|ZP_00795841.1\| COG0346: Lactoylglutathione lyase and related lyases [Yersinia pestis... gi\|145209764, gi... - gi\|145598068\|ref\|YP_001162144.1\| lactoylglutathione lyase [Yersinia pestis Pestoides F], gi\|14520976... gi\|149292121, gi... - gi\|149365708\|ref\|ZP_01887743.1\| glyoxalase I, Ni-dependent [Yersinia pestis CA88-4125], gi\|149292121... gi\|16122604, gi\|... - gi\|218929472\|ref\|YP_002347347.1\| lactoylglutathione lyase [Yersinia pestis CO92], gi\|16122604\|ref\|NP... gi\|25518338 - pir\|\|AF0290 lactoylglutathione lyase (EC 4.4.1.5) [imported] - Yersinia pestis (strain CO92) gi\|167470350 - gi\|167470350\|ref\|ZP_02335054.1\| lactoylglutathione lyase [Yersinia pestis FV-1]	135.0	[0..1]	[135..1]
gi\|32034458 - gi\|32034458\|ref\|ZP_00134640.1\| COG0346: Lactoylglutathione lyase and related lyases [Actinobacillus ... gi\|126207669, gi... - gi\|126207669\|ref\|YP_001052894.1\| lactoylglutathione lyase [Actinobacillus pleuropneumoniae L20], gi\|...	135.0	[0..1]	[135..1]

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Predicted Domain #1

Region A:
Residues: [1-135]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRILHTMLRV TNLERSIQFY QQVLGMRLLR TSDNPEYKYT LAFLGYDDEE NASVLELTYN  60
   61 WGVTEYELGT AYGHIAIGVE DIYATCDAVR QAGGKITREP GPVKGGKTVI AFVEDPDGYK 120
  121 IEFIENKHAQ SGLGN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.221849
Match:	1f9zA
Description:	Glyoxalase I (lactoylglutathione lyase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
lactoylglutathione lyase activity	3.91334658149719	bayes_pls_golite062009
carbon-sulfur lyase activity	1.44168339433372	bayes_pls_golite062009
catalytic activity	1.21778090213032	bayes_pls_golite062009
binding	0.78394104122898	bayes_pls_golite062009
protein binding	0.0335467332601391	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: