YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29831452, gi\|...
Organism:	Streptomyces avermitilis MA-4680
Length:	287 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29831452, gi|....

Description	E-value	Query Range	Subject Range
gi\|483836\|dbj\|BA... - NusG [Streptomyces griseus] gi\|483836, gi\|541483 - pir\|\|S41061 probable transcription antitermination factor nusG - Streptomyces griseus (strain IFO133...	264.0	[0..1]	[287..1]
gi\|483834 - gi\|483834\|dbj\|BAA04282.1\| NusG [Streptomyces coelicolor A3(2)] gi\|541480 - gi\|541480\|pir\|\|S41062 transcription antitermination factor nusG - Streptomyces coelicolor (strain A3...	255.0	[0..1]	[287..1]
gi\|109942286\|emb... - NusG protein [Streptomyces clavuligerus] gi\|109942286 - gi\|109942286\|emb\|CAJ84542.1\| NusG protein [Streptomyces clavuligerus]	242.0	[0..1]	[287..1]
NUSG_STRVG - Transcription termination/antitermination protein NusG OS=Streptomyces virginiae GN=nusG PE=1 SV=2	240.0	[0..1]	[287..1]
gi\|69284922, gi\|... - gi\|69284922\|ref\|ZP_00616621.1\| transcription antitermination protein NusG [Kineococcus radiotolerans...	239.0	[0..2]	[286..170]
gi\|215402414 - gi\|215402414\|ref\|ZP_03414595.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|194543022, gi... - gi\|81255499\|ref\|ZP_00879975.1\| COG0250: Transcription antiterminator [Mycobacterium tuberculosis C],... gi\|119700503, gi... - gi\|76785663\|ref\|ZP_00772828.1\| COG0250: Transcription antiterminator [Mycobacterium tuberculosis F11... gi\|148660413, gi... - gi\|167969069\|ref\|ZP_02551346.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|254363593, gi... - gi\|254363593\|ref\|ZP_04979639.1\| transcription antitermination protein nusG [Mycobacterium tuberculos... gi\|121636560, gi... - gi\|121636560\|ref\|YP_976783.1\| transcription antitermination protein NusG [Mycobacterium bovis BCG st... gi\|255098156 - gi\|255098156\|ref\|ZP_05327634.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|254817182 - gi\|254817182\|ref\|ZP_05222183.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|254549599 - gi\|254549599\|ref\|ZP_05140046.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|253797579, gi... - gi\|253797579\|ref\|YP_003030580.1\| transcription antitermination protein nusG [Mycobacterium tuberculo... gi\|215410186 - gi\|215410186\|ref\|ZP_03418994.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|215429474 - gi\|215429474\|ref\|ZP_03427393.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|215444758 - gi\|215444758\|ref\|ZP_03431510.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|218752287 - gi\|218752287\|ref\|ZP_03531083.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... NUSG_MYCTU - Transcription termination/antitermination protein NusG OS=Mycobacterium tuberculosis (strain ATCC 25... gi\|219556483 - gi\|219556483\|ref\|ZP_03535559.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... NUSG_MYCBO - Transcription antitermination protein nusG OS=Mycobacterium bovis GN=nusG PE=3 SV=1 NUSG_MYCBO - Transcription termination/antitermination protein NusG OS=Mycobacterium bovis (strain ATCC BAA-935 /... gi\|224989032, gi... - gi\|224989032\|ref\|YP_002643719.1\| transcription antitermination protein [Mycobacterium bovis BCG str.... NUSG_MYCTU - Transcription termination/antitermination protein NusG OS=Mycobacterium tuberculosis GN=nusG PE=1 SV... NUSG_MYCTO - Transcription termination/antitermination protein NusG OS=Mycobacterium tuberculosis (strain CDC 155...	230.0	[0..58]	[286..7]
gi\|221230497, gi... - gi\|221230497\|ref\|YP_002503913.1\| transcription antitermination protein nusG [Mycobacterium leprae Br... NUSG_MYCLE - Transcription antitermination protein nusG OS=Mycobacterium leprae GN=nusG PE=3 SV=1 NUSG_MYCLE - Transcription termination/antitermination protein NusG OS=Mycobacterium leprae (strain TN) GN=nusG P...	229.0	[0..64]	[286..3]

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Predicted Domain #1

Region A:
Residues: [1-87]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDPNLNDAI ESVESVDDEL DIVEGADVED EFEAADADAG EPAEEAAVHV EDESGTDLED  60
   61 DVDAADLAVS DEAEEAEEEA EPVDPVT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [88-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALREELRTLP GEWYVIHTYA GYENRVKTNL EQRAVSLNVE DFIFQAEVPQ EEVAQIKNGE  60
   61 RKTIRQNKLP GYVLVRMDLT NESWGVVRNT PGVTGFVGNA YDPYPLTLDE IVKMLAPEAE 120
  121 EKAAREAAEA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.522879
Match:	1nz8A
Description:	Solution Structure of the N-utilisation substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription termination factor activity	7.3828495299519	bayes_pls_golite062009
transcription regulator activity	3.63525538465601	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [218-287]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGKPAPQRKV EVQVLDFEVG DSVTVTDGPF ATLQATINEI NADSKKVKGL VEIFGRETPV  60
   61 ELSFDQIQKN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	14.69897
Match:	1nz9A
Description:	Solution Structure of the N-utilisation substance G (NusG) C-terminal (NGC) domain from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	2.40236111142017	bayes_pls_golite062009
structural molecule activity	2.11748533169546	bayes_pls_golite062009
transcription termination factor activity	2.09255447057062	bayes_pls_golite062009
transcription regulator activity	1.05039659348342	bayes_pls_golite062009
nucleic acid binding	0.761013355804059	bayes_pls_golite062009
binding	0.302568764609847	bayes_pls_golite062009
DNA binding	0.302556727687398	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: