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View Structure Prediction Details

Protein: PANC_CLOAB
Organism: Clostridium acetobutylicum ATCC 824
Length: 281 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PANC_CLOAB.

Description E-value Query
Range		 Subject
Range
PANC_THEMA - Pantothenate synthetase OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=...
PANC_THEMA - Pantothenate synthetase OS=Thermotoga maritima GN=panC PE=1 SV=1
 452.0 [0..1] [279..1]
PANC_THENE - Pantothenate synthetase OS=Thermotoga neapolitana GN=panC PE=3 SV=1
 446.0 [0..1] [279..1]
gi|196253301, gi... - gi|196253301|ref|ZP_03151934.1| pantoate--beta-alanine ligase [Clostridium thermocellum DSM 4150], g...
PANC_CLOTH - Pantothenate synthetase OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NC...
 439.0 [0..1] [281..1]
PANC_MOOTA - Pantothenate synthetase OS=Moorella thermoacetica (strain ATCC 39073) GN=panC PE=3 SV=1
 435.0 [0..1] [281..1]
PANC_DESHD - Pantothenate synthetase OS=Desulfitobacterium hafniense (strain DCB-2 / DSM 10664) GN=panC PE=3 SV=1
PANC_DESHY - Pantothenate synthetase OS=Desulfitobacterium hafniense (strain Y51) GN=panC PE=3 SV=1
 427.0 [0..1] [280..1]
gi|98661990 - gi|98661990|dbj|GAA01058.1| unnamed protein product [Pelotomaculum thermopropionicum SI]
 427.0 [0..1] [279..5]
gi|27262518 - gi|27262518|gb|AAN87540.1| Pantoate--beta-alanine ligase [Heliobacillus mobilis]
 425.0 [0..1] [281..27]
PANC_PSEPF - Pantothenate synthetase OS=Pseudomonas fluorescens (strain Pf0-1) GN=panC PE=3 SV=1
 423.0 [0..1] [281..1]
PANC_AQUAE - Pantothenate synthetase OS=Aquifex aeolicus (strain VF5) GN=panC PE=3 SV=1
PANC_AQUAE - Pantothenate synthetase OS=Aquifex aeolicus GN=panC PE=3 SV=1
 422.0 [0..3] [280..4]
PANC_THEPX - Pantothenate synthetase OS=Thermoanaerobacter sp. (strain X514) GN=panC PE=3 SV=1
gi|242232266, gi... - gi|242256189|ref|ZP_04801084.1| pantoate/beta-alanine ligase [Thermoanaerobacter sp. X513], gi|24223...
 420.0 [0..1] [278..1]

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Predicted Domain #1
Region A:
Residues: [1-281] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEILHSISDV KKYIKQWKKE GLTIGLVPTM GYLHDGHKSL IERASKENDK VIVSDFVNPI  60
   61 QFGPNEDLDV YPRDLDRDAE VCTKAGASIL FNPEPSEMYF DDAVTFVNSS KITDILCGAR 120
  121 RPGHFRGVCT VVTKLFNITC PDRAYFGEKD AQQVAVIKRM VRDLNFDIEI VACPIIREED 180
  181 GLAKSSRNSY LSSEERKAAT ILSKSLNLAK ELLDNGEKNV YNIKKAIIIE IGKEPLAKID 240
  241 YVEVVDSLSL KSVSKVQQSI LVAIAVYIGK IRLIDNFTWN I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 115.0
Match: 1ihoA
Description: Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
pantoate-beta-alanine ligase activity 2.65346774278189 bayes_pls_golite062009
catalytic activity 2.37674226834122 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 2.3170925937521 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 2.3170925937521 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 2.30614862840764 bayes_pls_golite062009
ligase activity 1.60661539954645 bayes_pls_golite062009
pantetheine-phosphate adenylyltransferase activity 1.25694296916214 bayes_pls_golite062009
adenylyltransferase activity 1.08055019963499 bayes_pls_golite062009
nicotinate-nucleotide adenylyltransferase activity 0.692499879958128 bayes_pls_golite062009
nicotinamide-nucleotide adenylyltransferase activity 0.567882194154248 bayes_pls_golite062009
nucleotidyltransferase activity 0.427749234863188 bayes_pls_golite062009
nucleic acid binding 0.264094677839184 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle