YRC Public Data Repository - Protein Structure Prediction

Protein:	HYPB_ECOL6
Organism:	Escherichia coli CFT073
Length:	290 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HYPB_ECOL6.

Description	E-value	Query Range	Subject Range
gi\|24053138, gi\|... - gi\|24114018\|ref\|NP_708528.1\| hydrogenase nickel incorporation protein HypB [Shigella flexneri 2a str... gi\|30064081, gi\|... - gi\|30064081\|ref\|NP_838252.1\| hydrogenase nickel incorporation protein HypB [Shigella flexneri 2a str... gi\|110806646, gi... - gi\|110806646\|ref\|YP_690166.1\| hydrogenase nickel incorporation protein HypB [Shigella flexneri 5 str...	266.0	[0..1]	[290..1]
gi\|75187449, gi\|... - gi\|75187449\|ref\|ZP_00700716.1\| COG0378: Ni2+-binding GTPase involved in regulation of expression and...	264.0	[0..1]	[290..1]
gi\|208808086, gi... - gi\|208808086\|ref\|ZP_03250423.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichi... gi\|208812172, gi... - gi\|208812172\|ref\|ZP_03253501.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichi... gi\|208818708, gi... - gi\|208818708\|ref\|ZP_03259028.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichi... gi\|209158440, gi... - gi\|209397040\|ref\|YP_002272191.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherich... gi\|168778711, gi... - gi\|189003631\|gb\|EDU72617.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|168787984, gi... - gi\|189372151\|gb\|EDU90567.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|168800191, gi... - gi\|189377494\|gb\|EDU95910.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|195938479 - gi\|195938479\|ref\|ZP_03083861.1\| hydrogenase nickel incorporation protein HypB [Escherichia coli O157... gi\|189357326, gi... - gi\|189357326\|gb\|EDU75745.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|168762872, gi... - gi\|189366894\|gb\|EDU85310.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|189362026, gi... - gi\|189362026\|gb\|EDU80445.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|187769563, gi... - gi\|187769563\|gb\|EDU33407.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|188015785, gi... - gi\|188015785\|gb\|EDU53907.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia co... gi\|25313851, gi\|... - pir\|\|G91076 hydrogenase isoenzyme HypB [imported] - Escherichia coli (strain O157:H7, substrain RIM... gi\|15832837, gi\|... - gi\|15832837\|ref\|NP_311610.1\| HypB [Escherichia coli O157:H7], gi\|13363054\|dbj\|BAB37006.1\| hydrogenas... gi\|15832837, gi\|... - gi\|15832837\|ref\|NP_311610.1\| hydrogenase nickel incorporation protein HypB [Escherichia coli O157:H7... gi\|254794668, gi... - gi\|254794668\|ref\|YP_003079505.1\| GTP hydrolase involved in nickel liganding into hydrogenases [Esche... gi\|217327146, gi... - gi\|217327146\|ref\|ZP_03443229.1\| hydrogenase isoenzymes nickel incorporation protein HypB [Escherichi...	263.0	[0..1]	[290..1]
gi\|83569908, gi\|... - gi\|83569908\|ref\|ZP_00921356.1\| COG0378: Ni2+-binding GTPase involved in regulation of expression and...	263.0	[0..1]	[290..1]
gi\|117624959, gi... - gi\|117624959\|ref\|YP_853947.1\| hydrogenase nickel incorporation protein HypB [Escherichia coli APEC O... gi\|218559717, gi... - gi\|218559717\|ref\|YP_002392630.1\| hydrogenase nickel incorporation protein HypB [Escherichia coli S88... gi\|91073661, gi\|... - gi\|91212087\|ref\|YP_542073.1\| hydrogenase nickel incorporation protein HypB [Escherichia coli UTI89],... gi\|226899689, gi... - gi\|237706649\|ref\|ZP_04537130.1\| hydrogenase nickel incorporation protein HypB [Escherichia sp. 3_2_5...	263.0	[0..1]	[290..1]
gi\|41776 - gi\|41776\|emb\|CAA38413.1\| hydrogenase isoenzyme hypB [Escherichia coli]	263.0	[0..1]	[290..1]
gi\|25313849 - pir\|\|G85921 hypothetical protein hypB [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|12517179, gi\|... - gi\|15803245\|ref\|NP_289277.1\| hydrogenase nickel incorporation protein HypB [Escherichia coli O157:H7...	262.0	[0..1]	[290..1]
gi\|81242241, gi\|... - gi\|82778093\|ref\|YP_404442.1\| hydrogenase nickel incorporation protein HypB [Shigella dysenteriae Sd1...	262.0	[0..1]	[290..1]
gi\|62128991, gi\|... - gi\|62181358\|ref\|YP_217775.1\| hydrogenase nickel incorporation protein HypB [Salmonella enterica subs...	261.0	[0..1]	[290..1]
gi\|50120173, gi\|... - gi\|50120173\|ref\|YP_049340.1\| hydrogenase nickel incorporation protein HypB [Pectobacterium atrosepti...	258.0	[0..1]	[287..1]

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Predicted Domain #1

Region A:
Residues: [1-63]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCTTCGCGEG NLYIEGDEHN PHSAFRSAPF APAARPKMKI TGIKAPEFTP SQTEEGDLHY  60
   61 GHG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.241	0.066	nucleoside-triphosphatase activity	a.52.1	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View	Download	0.208	0.028	nucleoside-triphosphatase activity	a.64.1	Saposin

Predicted Domain #2

Region A:
Residues: [64-290]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAGTHAPGMS QRRMLEVEID VLDKNNRLAE RNRARFAARK QLVLNLVSSP GSGKTTLLTE  60
   61 TLMRLKDSVP CAVIEGDQQT VNDAARIRAT GTPAIQVNTG KGCHLDAQMI ADAAPRLPLD 120
  121 DNGILFIENV GNLVCPASFD LGEKHKVAVL SVTEGEDKPL KYPHMFAAAS LMLLNKVDLL 180
  181 PYLNFDVEKC IACAREVNPE IEIILISATS GEGMDQWLNW LETQRCA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.0
Match:	2hf8A
Description:	No description for 2hf8A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits