YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|26110067, gi\|...
Organism:	Escherichia coli CFT073
Length:	123 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|26110067, gi|....

Description	E-value	Query Range	Subject Range
gi\|15833195, gi\|... - gi\|15833195\|ref\|NP_311968.1\| putative kinase [Escherichia coli O157:H7], gi\|13363414\|dbj\|BAB37364.1\|... gi\|209759318, gi... - pir\|\|D85966 probable kinase ygiG [imported] - Escherichia coli (strain O157:H7, substrain EDL933), ... gi\|15833195, gi\|... - gi\|15833195\|ref\|NP_311968.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'... gi\|15803600, gi\|... - gi\|15803600\|ref\|NP_289633.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'...	150.0	[0..1]	[123..1]
gi\|74313594, gi\|... - gi\|74313594\|ref\|YP_312013.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'...	149.0	[0..1]	[123..1]
gi\|58583747, gi\|... - gi\|58583747\|ref\|YP_202763.1\| dihydroneopterin aldolase [Xanthomonas oryzae pv. oryzae KACC10331], gi...	149.0	[0..2]	[119..24]
gi\|66770185, gi\|... - gi\|66770185\|ref\|YP_244947.1\| dihydroneopterin aldolase [Xanthomonas campestris pv. campestris str. 8... gi\|21233243, gi\|... - gi\|21233243\|ref\|NP_639160.1\| dihydroneopterin aldolase [Xanthomonas campestris pv. campestris str. A...	148.0	[0..2]	[118..1]
gi\|150841262, gi... - gi\|75436806\|ref\|ZP_00733347.1\| dihydroneopterin aldolase [Actinobacillus succinogenes 130Z], gi\|7427...	147.0	[0..1]	[116..1]
gi\|90311658, gi\|... - gi\|90407235\|ref\|ZP_01215422.1\| dihydroneopterin aldolase [Psychromonas sp. CNPT3], gi\|90311658\|gb\|EA...	147.0	[0..2]	[118..1]
gi\|21960494, gi\|... - gi\|22127405\|ref\|NP_670828.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'...	147.0	[0..1]	[120..1]
gi\|110344894, gi... - gi\|110643302\|ref\|YP_671032.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2... gi\|110616493, gi... - gi\|110806945\|ref\|YP_690465.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2... FOLB_ECOLI - Dihydroneopterin aldolase (EC 4.1.2.25) (DHNA) - Escherichia coli FOLB_SHIFL - Dihydroneopterin aldolase OS=Shigella flexneri GN=folB PE=3 SV=1 gi\|30042663, gi\|... - gi\|30064406\|ref\|NP_838577.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'... FOLB_ECOL6 - Dihydroneopterin aldolase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=folB PE=... gi\|169753618, gi... - gi\|170018690\|ref\|YP_001723644.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... gi\|227887781, gi... - gi\|227887781\|ref\|ZP_04005586.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate... gi\|238860076, gi... - gi\|238902169\|ref\|YP_002927965.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... gi\|242378608, gi... - gi\|251786335\|ref\|YP_003000639.1\| hypothetical protein B21_02878 [Escherichia coli BL21], gi\|24237860... gi\|254289755, gi... - gi\|254289755\|ref\|YP_003055503.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... EG11673 - dihydroneopterin aldolase and dihydroneopterin triphosphate 2'-epimerase / Dihydroneopterin aldolase gi\|253974906, gi... - gi\|254163005\|ref\|YP_003046113.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... gi\|218706683, gi... - gi\|218706683\|ref\|YP_002414202.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... gi\|115514495, gi... - gi\|117625371\|ref\|YP_855325.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2... gi\|124526031, gi... - gi\|124526031\|ref\|ZP_01698036.1\| dihydroneopterin aldolase [Escherichia coli B], gi\|124502135\|gb\|EAY4... gi\|89109828, gi\|... - gi\|89109828\|ref\|AP_003608.1\| bifunctional dihydroneopterin aldolase and dihydroneopterin triphosphat... gi\|169890436, gi... - gi\|170082601\|ref\|YP_001731921.1\| bifunctional dihydroneopterin aldolase and dihydroneopterin triphos... gi\|56480250, gi\|... - gi\|56480250\|ref\|NP_708868.2\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'... gi\|170521523, gi... - gi\|170683805\|ref\|YP_001745330.1\| dihydroneopterin aldolase [Escherichia coli SMS-3-5], gi\|170521523\|... gi\|194431768, gi... - gi\|194431768\|ref\|ZP_03064059.1\| dihydroneopterin aldolase [Shigella dysenteriae 1012], gi\|194420124\|... gi\|215266461, gi... - gi\|215488389\|ref\|YP_002330820.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... FOLB_ECOL6 - Dihydroneopterin aldolase OS=Escherichia coli O6 GN=folB PE=3 SV=1 gi\|218555628, gi... - gi\|218555628\|ref\|YP_002388541.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... gi\|218560145, gi... - gi\|218560145\|ref\|YP_002393058.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... gi\|218428927, gi... - gi\|218691363\|ref\|YP_002399575.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... gi\|218701829, gi... - gi\|218701829\|ref\|YP_002409458.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... gi\|157162532, gi... - gi\|75197011\|ref\|ZP_00707081.1\| COG1539: Dihydroneopterin aldolase [Escherichia coli HS], gi\|15716253... gi\|75212308, gi\|... - gi\|75212308\|ref\|ZP_00712332.1\| COG1539: Dihydroneopterin aldolase [Escherichia coli B171], gi\|194426... gi\|191168824, gi... - gi\|75227956\|ref\|ZP_00714651.1\| COG1539: Dihydroneopterin aldolase [Escherichia coli B7A], gi\|1911688... gi\|192959212, gi... - gi\|75239371\|ref\|ZP_00723342.1\| COG1539: Dihydroneopterin aldolase [Escherichia coli E110019], gi\|193... gi\|191172518, gi... - gi\|75240481\|ref\|ZP_00724409.1\| COG1539: Dihydroneopterin aldolase [Escherichia coli F11], gi\|1911725... gi\|193062104, gi... - gi\|75259991\|ref\|ZP_00731269.1\| COG1539: Dihydroneopterin aldolase [Escherichia coli E22], gi\|1930621... gi\|75511258, gi\|... - gi\|75511258\|ref\|ZP_00733956.1\| COG1539: Dihydroneopterin aldolase [Escherichia coli 53638], gi\|18849... EG11673 - dihydroneopterin aldolase and dihydroneopterin triphosphate 2'-epimerase / Dihydroneopterin aldolase gi\|83587504, gi\|... - gi\|83587504\|ref\|ZP_00926131.1\| COG1539: Dihydroneopterin aldolase [Escherichia coli 101-1], gi\|19443... gi\|75187868, gi\|... - gi\|75187868\|ref\|ZP_00701135.1\| COG1539: Dihydroneopterin aldolase [Escherichia coli E24377A], gi\|157...	146.0	[0..2]	[123..1]
gi\|75178957, gi\|... - gi\|75178957\|ref\|ZP_00698993.1\| COG1539: Dihydroneopterin aldolase [Shigella boydii BS512], gi\|187733...	146.0	[0..2]	[123..1]
gi\|68347245, gi\|... - gi\|70732946\|ref\|YP_262717.1\| dihydroneopterin aldolase [Pseudomonas fluorescens Pf-5], gi\|68347245\|g...	146.0	[0..2]	[116..1]

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Predicted Domain #1

Region A:
Residues: [1-123]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMDIVFIEQL SVITTIGVYD WEQTIEQKLV FDIEMAWDNR KAAKSDDVAD CLSYADIAET  60
   61 VVSHVEGARF ALVERVAEEV AELLLARFNS PWVRIKLSKP GAVARAANVG VIIERGNNLK 120
  121 ENN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.0
Match:	1nbuA
Description:	7,8-Dihydroneopterin Aldolase Complexed with Product From Mycobacterium Tuberculosis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
GTP cyclohydrolase I activity	4.32142445441644	bayes_pls_golite062009
cyclohydrolase activity	4.12134839958676	bayes_pls_golite062009
GTP cyclohydrolase activity	3.76376266092452	bayes_pls_golite062009
catalytic activity	2.57832156213163	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2.13367928146634	bayes_pls_golite062009
dihydroneopterin aldolase activity	2.05627605013559	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.46072575729571	bayes_pls_golite062009
6-pyruvoyltetrahydropterin synthase activity	0.11818000438771	bayes_pls_golite062009
lyase activity	0.0597333135477298	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: