YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|38199304
Organism:	Corynebacterium diphtheriae
Length:	263 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|38199304.

Description	E-value	Query Range	Subject Range
gi\|221230497, gi... - gi\|221230497\|ref\|YP_002503913.1\| transcription antitermination protein nusG [Mycobacterium leprae Br... NUSG_MYCLE - Transcription antitermination protein nusG OS=Mycobacterium leprae GN=nusG PE=3 SV=1 NUSG_MYCLE - Transcription termination/antitermination protein NusG OS=Mycobacterium leprae (strain TN) GN=nusG P...	251.0	[0..35]	[262..1]
gi\|215402414 - gi\|215402414\|ref\|ZP_03414595.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|194543022, gi... - gi\|81255499\|ref\|ZP_00879975.1\| COG0250: Transcription antiterminator [Mycobacterium tuberculosis C],... gi\|119700503, gi... - gi\|76785663\|ref\|ZP_00772828.1\| COG0250: Transcription antiterminator [Mycobacterium tuberculosis F11... gi\|148660413, gi... - gi\|167969069\|ref\|ZP_02551346.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|254363593, gi... - gi\|254363593\|ref\|ZP_04979639.1\| transcription antitermination protein nusG [Mycobacterium tuberculos... gi\|121636560, gi... - gi\|121636560\|ref\|YP_976783.1\| transcription antitermination protein NusG [Mycobacterium bovis BCG st... gi\|255098156 - gi\|255098156\|ref\|ZP_05327634.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|254817182 - gi\|254817182\|ref\|ZP_05222183.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|254549599 - gi\|254549599\|ref\|ZP_05140046.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|253797579, gi... - gi\|253797579\|ref\|YP_003030580.1\| transcription antitermination protein nusG [Mycobacterium tuberculo... gi\|215410186 - gi\|215410186\|ref\|ZP_03418994.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|215429474 - gi\|215429474\|ref\|ZP_03427393.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|215444758 - gi\|215444758\|ref\|ZP_03431510.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... gi\|218752287 - gi\|218752287\|ref\|ZP_03531083.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... NUSG_MYCTU - Transcription termination/antitermination protein NusG OS=Mycobacterium tuberculosis (strain ATCC 25... gi\|219556483 - gi\|219556483\|ref\|ZP_03535559.1\| transcription antitermination protein NusG [Mycobacterium tuberculos... NUSG_MYCBO - Transcription antitermination protein nusG OS=Mycobacterium bovis GN=nusG PE=3 SV=1 NUSG_MYCBO - Transcription termination/antitermination protein NusG OS=Mycobacterium bovis (strain ATCC BAA-935 /... gi\|224989032, gi... - gi\|224989032\|ref\|YP_002643719.1\| transcription antitermination protein [Mycobacterium bovis BCG str.... NUSG_MYCTU - Transcription termination/antitermination protein NusG OS=Mycobacterium tuberculosis GN=nusG PE=1 SV... NUSG_MYCTO - Transcription termination/antitermination protein NusG OS=Mycobacterium tuberculosis (strain CDC 155...	249.0	[0..21]	[262..2]
gi\|254776958 - gi\|254776958\|ref\|ZP_05218474.1\| transcription antitermination protein NusG [Mycobacterium avium subs... gi\|41410209, gi\|... - gi\|41410209\|ref\|NP_963045.1\| transcription antitermination protein NusG [Mycobacterium avium subsp. ... gi\|118167394, gi... - gi\|118466107\|ref\|YP_883656.1\| transcription antitermination protein NusG [Mycobacterium avium 104], ...	246.0	[0..11]	[262..6]
gi\|25027042, gi\|... - gi\|25027042\|ref\|NP_737096.1\| transcription antitermination protein NusG [Corynebacterium efficiens Y...	243.0	[0..2]	[263..19]
gi\|110818507, gi... - gi\|111018977\|ref\|YP_701949.1\| transcription antitermination protein NusG [Rhodococcus jostii RHA1], ...	240.0	[0..1]	[262..1]
gi\|89338459, gi\|... - gi\|89338459\|ref\|ZP_01191224.1\| transcription antitermination protein NusG:KOW [Mycobacterium flavesc...	240.0	[0..1]	[262..17]
gi\|29831452, gi\|... - gi\|29831452\|ref\|NP_826086.1\| transcription antitermination protein [Streptomyces avermitilis MA-4680...	234.0	[0..2]	[261..31]
gi\|90202745, gi\|... - gi\|90202745\|ref\|ZP_01205391.1\| transcription antitermination protein NusG:KOW [Mycobacterium vanbaal...	234.0	[0..1]	[262..1]
gi\|483836\|dbj\|BA... - NusG [Streptomyces griseus] gi\|483836, gi\|541483 - pir\|\|S41061 probable transcription antitermination factor nusG - Streptomyces griseus (strain IFO133...	234.0	[0..2]	[261..37]
gi\|98660440 - gi\|98660440\|dbj\|GAA02282.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	232.0	[0..69]	[262..4]

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Predicted Domain #1

Region A:
Residues: [1-196]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEENSFAEA FDEAVQNTIS AEAEEFTADG ELEVVEETAQ EADLTGGEKN EDAEYKARLR  60
   61 KYTRELKKLP GAWYIIQCYS GYENKVKTNL DMRAQTLEVE DSIFDVVVPI EQAIELRDGK 120
  121 RKLVKRKLLP GYVLVRMDIN DRSWSVVRDT PGVTSFVGNE GNATPVKHRD VAKFLMPQEA 180
  181 TESEAVNAEG EKVVAM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.39794
Match:	1nz8A
Description:	Solution Structure of the N-utilisation substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription termination factor activity	7.3828495299519	bayes_pls_golite062009
transcription regulator activity	3.63525538465601	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [197-263]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTDSTKPKTA VDFEVGEAVT ILSGAFASVS ATISGIDHEN AKIQALVSIF GRETPVELAF  60
   61 DQVEKIS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.221849
Match:	1nz9A
Description:	Solution Structure of the N-utilisation substance G (NusG) C-terminal (NGC) domain from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	2.40236111142017	bayes_pls_golite062009
structural molecule activity	2.11748533169546	bayes_pls_golite062009
transcription termination factor activity	2.09255447057062	bayes_pls_golite062009
transcription regulator activity	1.05039659348342	bayes_pls_golite062009
nucleic acid binding	0.761013355804059	bayes_pls_golite062009
binding	0.302568764609847	bayes_pls_golite062009
DNA binding	0.302556727687398	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: