YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|16759470
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. CT18
Length:	434 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16759470.

Description	E-value	Query Range	Subject Range
gi\|188494159, gi... - gi\|75514600\|ref\|ZP_00736855.1\| COG0524: Sugar kinases, ribokinase family [Escherichia coli 53638], g...	0.0	[1..434]	[1..434]
gi\|62179103, gi\|... - gi\|62179103\|ref\|YP_215520.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serovar C...	0.0	[1..434]	[16..449]
gi\|192959014, gi... - gi\|75239027\|ref\|ZP_00723009.1\| COG0524: Sugar kinases, ribokinase family [Escherichia coli E110019],... gi\|75238229, gi\|... - gi\|75238229\|ref\|ZP_00722230.1\| COG0524: Sugar kinases, ribokinase family [Escherichia coli F11], gi\|... gi\|190902441, gi... - gi\|75229362\|ref\|ZP_00715917.1\| COG0524: Sugar kinases, ribokinase family [Escherichia coli B7A], gi\|... gi\|75209767, gi\|... - gi\|75209767\|ref\|ZP_00709969.1\| COG0524: Sugar kinases, ribokinase family [Escherichia coli B171], gi... gi\|89107346, gi\|... - gi\|89107346\|ref\|AP_001126.1\| inosine/guanosine kinase [Escherichia coli str. K-12 substr. W3110], gi... gi\|82542970, gi\|... - gi\|82542970\|ref\|YP_406917.1\| inosine-guanosine kinase [Shigella boydii Sb227], gi\|81244381\|gb\|ABB650... gi\|74311056, gi\|... - gi\|74311056\|ref\|YP_309475.1\| inosine-guanosine kinase [Shigella sonnei Ss046], gi\|73854533\|gb\|AAZ872... gi\|192929185, gi... - gi\|75257878\|ref\|ZP_00729356.1\| COG0524: Sugar kinases, ribokinase family [Escherichia coli E22], gi\|... gi\|194432753, gi... - gi\|83570189\|ref\|ZP_00921635.1\| COG0524: Sugar kinases, ribokinase family [Shigella dysenteriae 1012]... gi\|157160004, gi... - gi\|75194697\|ref\|ZP_00704767.1\| COG0524: Sugar kinases, ribokinase family [Escherichia coli HS], gi\|1... gi\|157079690, gi... - gi\|75189545\|ref\|ZP_00702812.1\| COG0524: Sugar kinases, ribokinase family [Escherichia coli E24377A],... gi\|187731286, gi... - gi\|75177578\|ref\|ZP_00697659.1\| COG0524: Sugar kinases, ribokinase family [Shigella boydii BS512], gi... gi\|194437510, gi... - gi\|83587068\|ref\|ZP_00925698.1\| COG0524: Sugar kinases, ribokinase family [Escherichia coli 101-1], g... gi\|227838596, gi... - gi\|227884510\|ref\|ZP_04002315.1\| inosine-guanosine kinase [Escherichia coli 83972], gi\|227838596\|gb\|E... gi\|218703760, gi... - gi\|218703760\|ref\|YP_002411279.1\| inosine/guanosine kinase [Escherichia coli UMN026], gi\|218430857\|em... gi\|218698611, gi... - gi\|218698611\|ref\|YP_002406240.1\| inosine/guanosine kinase [Escherichia coli IAI39], gi\|218368597\|emb... gi\|168747845, gi... - gi\|188017634\|gb\|EDU55756.1\| inosine kinase [Escherichia coli O157:H7 str. EC4113], gi\|168747845\|ref\|... gi\|168760366, gi... - gi\|189369050\|gb\|EDU87466.1\| inosine kinase [Escherichia coli O157:H7 str. EC4501], gi\|168760366\|ref\|... gi\|189358115, gi... - gi\|189358115\|gb\|EDU76534.1\| inosine kinase [Escherichia coli O157:H7 str. EC4401], gi\|168754584\|ref\|... gi\|168774546, gi... - gi\|187769756\|gb\|EDU33600.1\| inosine kinase [Escherichia coli O157:H7 str. EC4196], gi\|168774546\|ref\|... gi\|189362353, gi... - gi\|189362353\|gb\|EDU80772.1\| inosine kinase [Escherichia coli O157:H7 str. EC4486], gi\|168768434\|ref\|... gi\|189379261, gi... - gi\|189379261\|gb\|EDU97677.1\| inosine kinase [Escherichia coli O157:H7 str. EC508], gi\|168798043\|ref\|Z... gi\|189002695, gi... - gi\|189002695\|gb\|EDU71681.1\| inosine kinase [Escherichia coli O157:H7 str. EC4076], gi\|168778973\|ref\|... gi\|115511858, gi... - gi\|117622734\|ref\|YP_851647.1\| inosine-guanosine kinase [Escherichia coli APEC O1], gi\|115511858\|gb\|A... INGK_ECOLI - Inosine-guanosine kinase (EC 2.7.1.73) - Escherichia coli gi\|124530271, gi... - gi\|124530271\|ref\|ZP_01700990.1\| Inosine kinase [Escherichia coli B], gi\|124499296\|gb\|EAY46787.1\| Ino... EG11102 - inosine /guanosine kinase / Inosine-guanosine kinase INGK_ECOL6 - Inosine-guanosine kinase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=gsk PE=3 ... gi\|215263629, gi... - gi\|215485557\|ref\|YP_002327988.1\| inosine/guanosine kinase [Escherichia coli O127:H6 str. E2348/69], ... gi\|209917693, gi... - gi\|209917693\|ref\|YP_002291777.1\| inosine-guanosine kinase [Escherichia coli SE11], gi\|209910952\|dbj\|... gi\|218547924, gi... - gi\|218547924\|ref\|YP_002381715.1\| inosine/guanosine kinase [Escherichia fergusonii ATCC 35469], gi\|21... gi\|217320732, gi... - gi\|217324511\|ref\|ZP_03440595.1\| inosine kinase [Escherichia coli O157:H7 str. TW14588], gi\|217320732... gi\|218364156, gi... - gi\|218557387\|ref\|YP_002390300.1\| inosine/guanosine kinase [Escherichia coli S88], gi\|218364156\|emb\|C... gi\|218553043, gi... - gi\|218553043\|ref\|YP_002385956.1\| inosine/guanosine kinase [Escherichia coli IAI1], gi\|218359811\|emb\|... gi\|218693939, gi... - gi\|218693939\|ref\|YP_002401606.1\| inosine/guanosine kinase [Escherichia coli 55989], gi\|218350671\|emb... gi\|218425904, gi... - gi\|218688340\|ref\|YP_002396552.1\| inosine/guanosine kinase [Escherichia coli ED1a], gi\|218425904\|emb\|... gi\|170080062, gi... - gi\|170080062\|ref\|YP_001729382.1\| inosine/guanosine kinase [Escherichia coli str. K-12 substr. DH10B]... gi\|170021135, gi... - gi\|170021135\|ref\|YP_001726089.1\| inosine kinase [Escherichia coli ATCC 8739], gi\|169756063\|gb\|ACA787... gi\|195936040 - gi\|195936040\|ref\|ZP_03081422.1\| inosine/guanosine kinase [Escherichia coli O157:H7 str. EC4024] gi\|170518407, gi... - gi\|170680689\|ref\|YP_001742622.1\| inosine kinase [Escherichia coli SMS-3-5], gi\|170518407\|gb\|ACB16585... gi\|208732367, gi... - gi\|208815719\|ref\|ZP_03256898.1\| inosine kinase [Escherichia coli O157:H7 str. EC4045], gi\|208732367\|... gi\|208806237, gi... - gi\|208806237\|ref\|ZP_03248574.1\| inosine kinase [Escherichia coli O157:H7 str. EC4206], gi\|208726038\|... gi\|209161282, gi... - gi\|209399882\|ref\|YP_002269128.1\| inosine kinase [Escherichia coli O157:H7 str. EC4115], gi\|209161282... gi\|208823001, gi... - gi\|208823001\|ref\|ZP_03263319.1\| inosine kinase [Escherichia coli O157:H7 str. EC4042], gi\|208737194\|... gi\|226898735, gi... - gi\|237707525\|ref\|ZP_04538006.1\| inosine/guanosine kinase [Escherichia sp. 3_2_53FAA], gi\|226898735\|g... gi\|238861511, gi... - gi\|238899764\|ref\|YP_002925560.1\| inosine/guanosine kinase [Escherichia coli BW2952], gi\|238861511\|gb... gi\|251783985, gi... - gi\|251783985\|ref\|YP_002998289.1\| hypothetical protein B21_00433 [Escherichia coli BL21], gi\|24237625... gi\|253325577, gi... - gi\|254287350\|ref\|YP_003053098.1\| inosine/guanosine kinase [Escherichia coli BL21(DE3)], gi\|253976657... gi\|254160546, gi... - gi\|254160546\|ref\|YP_003043654.1\| inosine/guanosine kinase [Escherichia coli B str. REL606], gi\|25397... gi\|254591060, gi... - gi\|254791660\|ref\|YP_003076497.1\| inosine/guanosine kinase [Escherichia coli O157:H7 str. TW14359], g... gi\|110640738, gi... - gi\|110640738\|ref\|YP_668466.1\| inosine-guanosine kinase [Escherichia coli 536], gi\|110342330\|gb\|ABG68... gi\|91209551, gi\|... - gi\|91209551\|ref\|YP_539537.1\| inosine-guanosine kinase [Escherichia coli UTI89], gi\|91071125\|gb\|ABE06... gi\|13359987, gi\|... - gi\|15829784\|ref\|NP_308557.1\| inosine-guanosine kinase [Escherichia coli O157:H7 str. Sakai], gi\|1335... INGK_ECO57 - Inosine-guanosine kinase OS=Escherichia coli O157:H7 GN=gsk PE=3 SV=1 EG11102 - inosine /guanosine kinase / Inosine-guanosine kinase gi\|15800206, gi\|... - gi\|15800206\|ref\|NP_286218.1\| inosine-guanosine kinase [Escherichia coli O157:H7 EDL933], gi\|12513347... INGK_ECOL6 - Inosine-guanosine kinase OS=Escherichia coli O6 GN=gsk PE=3 SV=1	0.0	[1..434]	[1..434]
gi\|16763871, gi\|... - gi\|16763871\|ref\|NP_459486.1\| inosine-guanosine kinase [Salmonella typhimurium LT2], gi\|16418999\|gb\|A... gi\|207855970, gi... - gi\|207855970\|ref\|YP_002242621.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serov... gi\|204930596, gi... - gi\|204930596\|ref\|ZP_03221526.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Javiana ... gi\|205271579, gi... - gi\|205351798\|ref\|YP_002225599.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serov... gi\|56414354, gi\|... - gi\|56414354\|ref\|YP_151429.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serovar P... gi\|197363274, gi... - gi\|197363274\|ref\|YP_002142911.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serov... gi\|200390186, gi... - gi\|200390186\|ref\|ZP_03216797.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Virchow ... gi\|197251769, gi... - gi\|197251769\|ref\|YP_002145475.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Agona s... gi\|197261690, gi... - gi\|197261690\|ref\|ZP_03161764.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Saintpau... gi\|194451001, gi... - gi\|194451001\|ref\|YP_002044524.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Heidelb... gi\|194712673, gi... - gi\|194737171\|ref\|YP_002113522.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Schwarz... gi\|195631744, gi... - gi\|195631744\|gb\|EDX50264.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Newport str.... gi\|194443043, gi... - gi\|194443043\|ref\|YP_002039735.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Newport... gi\|168240323, gi... - gi\|205340150\|gb\|EDZ26914.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Heidelberg s... gi\|205349759, gi... - gi\|205349759\|gb\|EDZ36390.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Hadar str. R... gi\|168239007, gi... - gi\|197288173\|gb\|EDY27558.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Schwarzengru... gi\|238911379 - gi\|238911379\|ref\|ZP_04655216.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serova...	0.0	[1..434]	[1..434]
gi\|77974254, gi\|... - gi\|77974254\|ref\|ZP_00829795.1\| COG0524: Sugar kinases, ribokinase family [Yersinia frederiksenii ATC...	0.0	[1..434]	[1..434]
gi\|110804503, gi... - gi\|110804503\|ref\|YP_688023.1\| inosine-guanosine kinase [Shigella flexneri 5 str. 8401], gi\|110614051... gi\|30040221, gi\|... - gi\|30061977\|ref\|NP_836148.1\| inosine-guanosine kinase [Shigella flexneri 2a str. 2457T], gi\|30040221... gi\|24111860, gi\|... - gi\|24111860\|ref\|NP_706370.1\| inosine-guanosine kinase [Shigella flexneri 2a str. 301], gi\|24050656\|g...	0.0	[1..434]	[1..434]
gi\|81239941, gi\|... - gi\|82775793\|ref\|YP_402140.1\| inosine-guanosine kinase [Shigella dysenteriae Sd197], gi\|81239941\|gb\|A...	0.0	[1..434]	[1..434]
gi\|77962386, gi\|... - gi\|77962386\|ref\|ZP_00826207.1\| COG0524: Sugar kinases, ribokinase family [Yersinia mollaretii ATCC 4...	0.0	[1..434]	[1..434]
gi\|22124990, gi\|... - gi\|22124990\|ref\|NP_668413.1\| inosine-guanosine kinase [Yersinia pestis KIM], gi\|21957835\|gb\|AAM84664... gi\|25514770 - pir\|\|AD0376 inosine kinase (EC 2.7.1.73) [imported] - Yersinia pestis (strain CO92) gi\|51595365, gi\|... - gi\|51595365\|ref\|YP_069556.1\| inosine-guanosine kinase [Yersinia pseudotuberculosis IP 32953], gi\|515... gi\|45440675, gi\|... - gi\|45440675\|ref\|NP_992214.1\| inosine-guanosine kinase [Yersinia pestis biovar Microtus str. 91001], ... gi\|15981045, gi\|... - gi\|218930137\|ref\|YP_002348012.1\| inosine-guanosine kinase [Yersinia pestis CO92], gi\|16123269\|ref\|NP... Q66DM8\|Q66DM8_YERPS - Inosine-guanosine kinase - Yersinia pseudotuberculosis gi\|165916007, gi... - gi\|89103576\|ref\|ZP_01176147.1\| COG0524: Sugar kinases, ribokinase family [Yersinia pestis biovar Ori... gi\|108808582, gi... - gi\|108808582\|ref\|YP_652498.1\| inosine-guanosine kinase [Yersinia pestis Antiqua], gi\|108780495\|gb\|AB... gi\|229901387, gi... - gi\|229901387\|ref\|ZP_04516509.1\| inosine-guanosine kinase [Yersinia pestis Nepal516], gi\|229681316\|gb... gi\|165920407, gi... - gi\|165927653\|ref\|ZP_02223485.1\| inosine-guanosine kinase [Yersinia pestis biovar Orientalis str. F19... gi\|149365047, gi... - gi\|149365047\|ref\|ZP_01887082.1\| inosine-guanosine kinase [Yersinia pestis CA88-4125], gi\|149291460\|g... gi\|145211689, gi... - gi\|145599993\|ref\|YP_001164069.1\| inosine-guanosine kinase [Yersinia pestis Pestoides F], gi\|14521168... gi\|166204464, gi... - gi\|166214335\|ref\|ZP_02240370.1\| inosine-guanosine kinase [Yersinia pestis biovar Antiqua str. B42003... gi\|166011192, gi... - gi\|166011192\|ref\|ZP_02232090.1\| inosine-guanosine kinase [Yersinia pestis biovar Antiqua str. E19790... gi\|166958323, gi... - gi\|167422732\|ref\|ZP_02314485.1\| inosine-guanosine kinase [Yersinia pestis biovar Orientalis str. MG0... gi\|167051702, gi... - gi\|167399198\|ref\|ZP_02304722.1\| inosine-guanosine kinase [Yersinia pestis biovar Antiqua str. UG05-0... gi\|77632917, gi\|... - gi\|77632917\|ref\|ZP_00795086.1\| COG0524: Sugar kinases, ribokinase family [Yersinia pestis Angola], g... gi\|167469517 - gi\|167469517\|ref\|ZP_02334221.1\| inosine-guanosine kinase [Yersinia pestis FV-1] gi\|77631973, gi\|... - gi\|77631973\|ref\|ZP_00794559.1\| COG0524: Sugar kinases, ribokinase family [Yersinia pseudotuberculosi... gi\|167057998, gi... - gi\|167423828\|ref\|ZP_02315581.1\| inosine-guanosine kinase [Yersinia pestis biovar Mediaevalis str. K1... gi\|186697413, gi... - gi\|186894387\|ref\|YP_001871499.1\| ribokinase-like domain-containing protein [Yersinia pseudotuberculo... gi\|169751927, gi... - gi\|170025393\|ref\|YP_001721898.1\| inosine kinase [Yersinia pseudotuberculosis YPIII], gi\|169751927\|gb... gi\|229838695, gi... - gi\|229838695\|ref\|ZP_04458854.1\| inosine-guanosine kinase [Yersinia pestis biovar Orientalis str. PEX... gi\|229701071, gi... - gi\|229896148\|ref\|ZP_04511318.1\| inosine-guanosine kinase [Yersinia pestis Pestoides A], gi\|229701071... gi\|229899262, gi... - gi\|229899262\|ref\|ZP_04514405.1\| inosine-guanosine kinase [Yersinia pestis biovar Orientalis str. Ind...	1.0E-99	[1..434]	[1..434]
gi\|77979346, gi\|... - gi\|77979346\|ref\|ZP_00834765.1\| COG0524: Sugar kinases, ribokinase family [Yersinia intermedia ATCC 2...	2.0E-99	[1..434]	[1..434]

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Predicted Domain #1

Region A:
Residues: [1-434]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFPGKRKSK HYFPVNARDP LLQQIQPEQE TNASWVVGID QTLVDIEAKV DDDFITRYGL  60
   61 SAGHSLVIED ELAEKLYQEL TRENLITHQF AGGTIGNTMH NYSVLADDRS VLLGVMCSNI 120
  121 EIGSYAYRYL CNTSSRTDLN YLQAVDGPIG RCFTLIGESG ERTFAISPGH MNQLRAESIP 180
  181 EAVIAGASAL VLTSYLVRCK PGEPMPDATM KAIEYAKKHN VPVVMTLGTK FVIADNPQWW 240
  241 QAFLKENVSI LAMNEEEAEA LTGENDPLLA ADKALDWVDL VLCTAGPIGL YMAGFTEEEA 300
  301 KRKTQHPLLP GAIAEFNQYE FSRAMRHKDC TNPLRVYSHI APYMGGPEKI MNTNGAGDGA 360
  361 LAALLHDITA NSYHRSNVPN SSKHKFTWLT YSSLAQVCKY ANRVSYQVLN QHSPRLTRGL 420
  421 PEREDSLEES YWDR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.39794
Match:	1vm7A
Description:	Crystal structure of Ribokinase (TM0960) from Thermotoga maritima at 2.15 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
kinase activity	5.04206608489376	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	4.1090502214964	bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity	3.2648227748401	bayes_pls_golite062009
catalytic activity	2.11518580948187	bayes_pls_golite062009
transferase activity	1.65599843675995	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.53929419091344	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: