YRC Public Data Repository - Protein Structure Prediction

Protein:	ALLB_SALTI
Organism:	Salmonella enterica subsp. enterica serovar Typhi
Length:	453 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALLB_SALTI.

Description	E-value	Query Range	Subject Range
gi\|194423619, gi... - gi\|83587037\|ref\|ZP_00925667.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... gi\|251784018, gi... - gi\|251784018\|ref\|YP_002998322.1\| hypothetical protein B21_00467 [Escherichia coli BL21], gi\|24237629... gi\|253972481, gi... - gi\|254160580\|ref\|YP_003043688.1\| allantoinase [Escherichia coli B str. REL606], gi\|253972481\|gb\|ACT3... gi\|253325544, gi... - gi\|254287384\|ref\|YP_003053132.1\| allantoinase [Escherichia coli BL21(DE3)], gi\|253976691\|gb\|ACT42361...	1.0E-89	[1..453]	[1..453]
ALLB_ECODH - Allantoinase OS=Escherichia coli (strain K12 / DH10B) GN=allB PE=3 SV=1 ALLB_ECOBW - Allantoinase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=allB PE=3 SV=1 ALN_ECOLI - Allantoinase (EC 3.5.2.5) - Escherichia coli gi\|89107380, gi\|... - gi\|89107380\|ref\|AP_001160.1\| allantoinase [Escherichia coli str. K-12 substr. W3110], gi\|85674650\|db... EG13619 - allantoinase / Allantoinase: allantoin for anaerobic nitrogen; tetrameric EG13619 - allantoinase / Allantoinase: allantoin for anaerobic nitrogen; tetrameric	1.0E-89	[1..453]	[1..453]
gi\|188492046, gi... - gi\|75514630\|ref\|ZP_00736885.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... ALLB_ECOLC - Allantoinase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=allB PE=3 SV=1 gi\|124529321, gi... - gi\|124529321\|ref\|ZP_01700355.1\| Allantoinase [Escherichia coli B], gi\|124499921\|gb\|EAY47401.1\| Allan...	2.0E-89	[1..453]	[1..453]
ALLB_SALCH - Allantoinase OS=Salmonella choleraesuis GN=allB PE=3 SV=1 ALLB_SALCH - Allantoinase OS=Salmonella choleraesuis (strain SC-B67) GN=allB PE=3 SV=1 ALLB_SALCH - Allantoinase OS=Salmonella choleraesuis GN=allB PE=3 SV=1	3.0E-89	[1..453]	[1..453]
gi\|192929171, gi... - gi\|75257848\|ref\|ZP_00729326.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... gi\|75238997, gi\|... - gi\|75238997\|ref\|ZP_00722979.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... gi\|190901848, gi... - gi\|75228714\|ref\|ZP_00715331.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... gi\|194429580, gi... - gi\|75209184\|ref\|ZP_00709435.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... ALLB_ECO55 - Allantoinase OS=Escherichia coli (strain 55989 / EAEC) GN=allB PE=3 SV=1 ALLB_ECOSE - Allantoinase OS=Escherichia coli (strain SE11) GN=allB PE=3 SV=1 ALLB_ECO8A - Allantoinase OS=Escherichia coli O8 (strain IAI1) GN=allB PE=3 SV=1	3.0E-89	[1..453]	[1..453]
gi\|227884480, gi... - gi\|227884480\|ref\|ZP_04002285.1\| allantoinase [Escherichia coli 83972], gi\|227838566\|gb\|EEJ49032.1\| a... ALLB_ECOUT - Allantoinase OS=Escherichia coli (strain UTI89 / UPEC) GN=allB PE=3 SV=1 gi\|237707488, gi... - gi\|237707488\|ref\|ZP_04537969.1\| allantoinase [Escherichia sp. 3_2_53FAA], gi\|226898698\|gb\|EEH84957.1... ALLB_ECOL5 - Allantoinase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=allB PE=3 SV=1 ALLB_ECO45 - Allantoinase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=allB PE=3 SV=1 ALLB_ECOL6 - Allantoinase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=allB PE=3 SV=1 ALLB_ECOL6 - Allantoinase OS=Escherichia coli O6 GN=allB PE=3 SV=1 ALLB_ECO27 - Allantoinase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=allB PE=3 SV=1 gi\|190907387, gi... - gi\|75240705\|ref\|ZP_00724612.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... ALLB_ECO81 - Allantoinase OS=Escherichia coli O81 (strain ED1a) GN=allB PE=3 SV=1 sp\|B7UKI9\|ALLB_ECO27 - Allantoinase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=allB PE=3 SV=1 ALLB_ECOK1 - Allantoinase OS=Escherichia coli O1:K1 / APEC GN=allB PE=3 SV=1	5.0E-89	[1..453]	[1..453]
ALLB_ECOHS - Allantoinase OS=Escherichia coli O9:H4 (strain HS) GN=allB PE=3 SV=1	1.0E-88	[1..453]	[1..453]
gi\|77976883, gi\|... - gi\|77976883\|ref\|ZP_00832350.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Yersinia ...	1.0E-88	[1..453]	[1..453]
ALLB_ECO24 - Allantoinase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=allB PE=3 SV=1	2.0E-88	[1..453]	[1..453]
gi\|28211428, gi\|... - gi\|28211428\|ref\|NP_782372.1\| dihydropyrimidinase [Clostridium tetani E88], gi\|28203869\|gb\|AAO36309.1...	1.0E-81	[3..451]	[4..456]

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Predicted Domain #1

Region A:
Residues: [1-453]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFDLIIKNG TVILENEARV IDIAVQGGKI AAIGENLGEA KNVLDATGLI VSPGMVDAHT  60
   61 HISEPGRTHW EGYETGTRAA AKGGITTMIE MPLNQLPATV DRETIELKFD AAKGKLTIDA 120
  121 AQLGGLVSYN LDRLHELDEV GVVGFKCFVA TCGDRGIDND FRDVNDWQFY KGAQKLGEMD 180
  181 QTVLVHCENA LICDELGEEA KREGRVTAHD YVASRPVFTE VEAIRRVLYL AKAAGCRLHV 240
  241 CHISSPEGVE EVTRARQEGQ DVTCESCPHY FVLDTDQFEE IGTLAKCSPP IRDQENQKGM 300
  301 WEKLFNGEID CLVSDHSPCP PEMKAGNIMQ AWGGIAGLQN CMDVMFDEAV QKRGMSLPMF 360
  361 GKLMATNAAD IFGLKHKGRI APGKDADLVF IQPDSSYVLK NEDLEYRHKV SPYVGRTIGA 420
  421 RITKTILRGD VIYDIEHGFP VPPKGQFILK HQQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	73.522879
Match:	1gkrA
Description:	L-hydantoinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
uracil binding	2.6045173443981	bayes_pls_golite062009
pyrimidine binding	2.6045173443981	bayes_pls_golite062009
allantoinase activity	2.45571277189844	bayes_pls_golite062009
dihydroorotase activity	2.32070383330692	bayes_pls_golite062009
dihydropyrimidinase activity	2.27856136692645	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2.20489529944693	bayes_pls_golite062009
hydrolase activity	2.17584977880576	bayes_pls_golite062009
deaminase activity	1.79186203771221	bayes_pls_golite062009
catalytic activity	1.70199291046899	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.60895003474033	bayes_pls_golite062009
adenine deaminase activity	1.4081199504179	bayes_pls_golite062009
thymine binding	1.34528530211689	bayes_pls_golite062009
AMP deaminase activity	0.8498975324894	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	0.573107361273483	bayes_pls_golite062009
binding	0.420164638111423	bayes_pls_golite062009
guanine deaminase activity	0.134430884998957	bayes_pls_golite062009
protein binding	0.0854348074331311	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: