YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29142601, gi\|...
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. Ty2
Length:	406 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29142601, gi|....

Description	E-value	Query Range	Subject Range
gi\|62126906, gi\|... - gi\|62179273\|ref\|YP_215690.1\| N-acetylglucosamine operon transcriptional repressor [Salmonella enteri...	3.0E-95	[1..406]	[1..406]
NAGC_SHIFL - N-acetylglucosamine repressor OS=Shigella flexneri GN=nagC PE=3 SV=1 gi\|24112038, gi\|... - gi\|24112038\|ref\|NP_706548.1\| transcriptional repressor of nag (N-acetylglucosamine) operon [Shigella... NAGC_ECOL6 - N-acetylglucosamine repressor OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=nagC... gi\|30040394, gi\|... - gi\|30062149\|ref\|NP_836320.1\| transcriptional repressor of nag (N-acetylglucosamine) operon [Shigella... NAGC_ECO57 - N-acetylglucosamine repressor OS=Escherichia coli O157:H7 GN=nagC PE=3 SV=1 EG10636 - N-acetylglucosamine-inducible nag divergent operon transcriptional repressor / N-acetylglucosamine-i... gi\|12513574, gi\|... - gi\|15800378\|ref\|NP_286390.1\| transcriptional repressor of nag (N-acetylglucosamine) operon [Escheric... gi\|189364916, gi... - gi\|189364916\|gb\|EDU83332.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC4501], gi... gi\|189363443, gi... - gi\|189363443\|gb\|EDU81862.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC4486], gi... gi\|187766944, gi... - gi\|187766944\|gb\|EDU30788.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC4196], gi... gi\|189002887, gi... - gi\|189002887\|gb\|EDU71873.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC4076], gi... gi\|189373501, gi... - gi\|189373501\|gb\|EDU91917.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC869], gi\|... gi\|168802823, gi... - gi\|189375297\|gb\|EDU93713.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC508], gi\|... gi\|169755906, gi... - gi\|170020978\|ref\|YP_001725932.1\| ROK family protein [Escherichia coli ATCC 8739], gi\|169755906\|gb\|AC... gi\|170080345, gi... - gi\|170080345\|ref\|YP_001729665.1\| DNA-binding transcriptional dual regulator, repressor of N-acetylgl... NAGC_ECOLI - N-acetylglucosamine repressor - Escherichia coli gi\|188013592, gi... - gi\|188013592\|gb\|EDU51714.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC4113], gi... gi\|189354841, gi... - gi\|189354841\|gb\|EDU73260.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC4401], gi... gi\|217320462, gi... - gi\|217324241\|ref\|ZP_03440325.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. TW14588... gi\|218553209, gi... - gi\|218553209\|ref\|YP_002386122.1\| DNA-binding transcriptional dual regulator, repressor of N-acetylgl... gi\|218364366, gi... - gi\|218557597\|ref\|YP_002390510.1\| DNA-binding transcriptional dual regulator, repressor of N-acetylgl... gi\|218688482, gi... - gi\|218688482\|ref\|YP_002396694.1\| DNA-binding transcriptional dual regulator, repressor of N-acetylgl... gi\|218350836, gi... - gi\|218694104\|ref\|YP_002401771.1\| DNA-binding transcriptional dual regulator, repressor of N-acetylgl... gi\|218369016, gi... - gi\|218699030\|ref\|YP_002406659.1\| DNA-binding transcriptional dual regulator, repressor of N-acetylgl... gi\|218704000, gi... - gi\|218704000\|ref\|YP_002411519.1\| DNA-binding transcriptional dual regulator, repressor of N-acetylgl... gi\|170519685, gi... - gi\|170681967\|ref\|YP_001742785.1\| N-acetylglucosamine repressor [Escherichia coli SMS-3-5], gi\|170519... gi\|195939401 - gi\|195939401\|ref\|ZP_03084783.1\| DNA-binding transcriptional dual regulator, repressor of N-acetylglu... gi\|208725648, gi... - gi\|208805847\|ref\|ZP_03248184.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC4206]... gi\|208814855, gi... - gi\|208814855\|ref\|ZP_03256034.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC4045]... gi\|208737054, gi... - gi\|208822861\|ref\|ZP_03263179.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC4042]... gi\|209400377, gi... - gi\|209400377\|ref\|YP_002269302.1\| N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC4115... gi\|209917927, gi... - gi\|209917927\|ref\|YP_002292011.1\| N-acetylglucosamine repressor [Escherichia coli SE11], gi\|209911186... gi\|215263770, gi... - gi\|215485698\|ref\|YP_002328129.1\| DNA-binding transcriptional dual regulator, repressor of the N-acet... gi\|251784166, gi... - gi\|251784166\|ref\|YP_002998470.1\| hypothetical protein B21_00624 [Escherichia coli BL21], gi\|24237643... gi\|238899942, gi... - gi\|238899942\|ref\|YP_002925738.1\| DNA-binding transcriptional dual regulator, repressor of N-acetylgl... gi\|237707366, gi... - gi\|237707366\|ref\|ZP_04537847.1\| DNA-binding transcriptional dual regulator [Escherichia sp. 3_2_53FA... gi\|227838445, gi... - gi\|227884359\|ref\|ZP_04002164.1\| transcriptional repressor of nag (N-acetylglucosamine) operon [Esche... NAGC_ECOL6 - N-acetylglucosamine repressor OS=Escherichia coli O6 GN=nagC PE=3 SV=1 EG10636 - N-acetylglucosamine-inducible nag divergent operon transcriptional repressor / N-acetylglucosamine-i... gi\|191173953, gi... - gi\|75237582\|ref\|ZP_00721613.1\| COG1940: Transcriptional regulator/sugar kinase [Escherichia coli F11... gi\|193063368, gi... - gi\|75258598\|ref\|ZP_00730005.1\| COG1940: Transcriptional regulator/sugar kinase [Escherichia coli E22... gi\|193071733, gi... - gi\|75214652\|ref\|ZP_00713169.1\| COG1940: Transcriptional regulator/sugar kinase [Escherichia coli E11... gi\|191169353, gi... - gi\|75227338\|ref\|ZP_00714121.1\| COG1940: Transcriptional regulator/sugar kinase [Escherichia coli B7A... gi\|82775945, gi\|... - gi\|82775945\|ref\|YP_402292.1\| transcriptional repressor of N-acetylglucosamine operon [Shigella dysen... gi\|81244522, gi\|... - gi\|82543111\|ref\|YP_407058.1\| transcriptional repressor of nag operon [Shigella boydii Sb227], gi\|812... gi\|115512000, gi... - gi\|117622876\|ref\|YP_851789.1\| transcriptional repressor of nag [Escherichia coli APEC O1], gi\|115512... gi\|188496293, gi... - gi\|75511076\|ref\|ZP_00733808.1\| COG1940: Transcriptional regulator/sugar kinase [Escherichia coli 536... gi\|124499703, gi... - gi\|124529700\|ref\|ZP_01700607.1\| ROK family protein [Escherichia coli B], gi\|124499703\|gb\|EAY47187.1... gi\|74311204, gi\|... - gi\|74311204\|ref\|YP_309623.1\| transcriptional repressor of nag (N-acetylglucosamine) operon [Shigella... gi\|83584551, gi\|... - gi\|83584551\|ref\|ZP_00923225.1\| COG1940: Transcriptional regulator/sugar kinase [Escherichia coli 101... gi\|157065834, gi... - gi\|75194843\|ref\|ZP_00704913.1\| COG1940: Transcriptional regulator/sugar kinase [Escherichia coli HS]... gi\|194429727, gi... - gi\|75209021\|ref\|ZP_00709281.1\| COG1940: Transcriptional regulator/sugar kinase [Escherichia coli B17... gi\|75175181, gi\|... - gi\|75175181\|ref\|ZP_00695502.1\| COG1940: Transcriptional regulator/sugar kinase [Shigella boydii BS51... gi\|75189704, gi\|... - gi\|75189704\|ref\|ZP_00702971.1\| COG1940: Transcriptional regulator/sugar kinase [Escherichia coli E24... gi\|110342479, gi... - gi\|110640887\|ref\|YP_668615.1\| N-acetylglucosamine repressor NagC [Escherichia coli 536], gi\|11034247... gi\|110614235, gi... - gi\|110804687\|ref\|YP_688207.1\| transcriptional repressor of nag (N-acetylglucosamine) operon [Shigell... gi\|89107534, gi\|... - gi\|89107534\|ref\|AP_001314.1\| DNA-binding transcriptional dual regulator [Escherichia coli str. K-12 ... gi\|254591228, gi... - gi\|254791828\|ref\|YP_003076665.1\| DNA-binding transcriptional dual regulator, repressor of N-acetylgl... gi\|91071282, gi\|... - gi\|91209708\|ref\|YP_539694.1\| transcriptional repressor of nag (N-acetylglucosamine) operon [Escheric... gi\|254160744, gi... - gi\|254160744\|ref\|YP_003043852.1\| DNA-binding transcriptional dual regulator, repressor of N-acetylgl... gi\|15829960, gi\|... - gi\|15829960\|ref\|NP_308733.1\| transcriptional repressor of N-acetylglucosamine operon [Escherichia co... gi\|254287532, gi... - gi\|254287532\|ref\|YP_003053280.1\| DNA-binding transcriptional dual regulator, repressor of N-acetylgl...	1.0E-94	[1..406]	[1..406]
lcl\|NC_016856.1_... - [gene=nagC] [protein=N-acetylglucosamine operon transcriptional repressor] [protein_id=YP_005236394.... gi\|205328896, gi... - gi\|205328896\|gb\|EDZ15660.1\| N-acetylglucosamine repressor [Salmonella enterica subsp. enterica serov... gi\|16764052, gi\|... - gi\|16764052\|ref\|NP_459667.1\| N-acetylglucosamine operon transcriptional repressor [Salmonella typhim...	1.0E-94	[1..406]	[1..406]
gi\|194434447, gi... - gi\|83569126\|ref\|ZP_00920586.1\| COG1940: Transcriptional regulator/sugar kinase [Shigella dysenteriae...	3.0E-94	[1..406]	[1..406]
gi\|42080 - gi\|42080\|emb\|CAA32354.1\| unnamed protein product [Escherichia coli]	3.0E-93	[1..406]	[1..406]
gi\|77973053, gi\|... - gi\|77973053\|ref\|ZP_00828606.1\| COG1940: Transcriptional regulator/sugar kinase [Yersinia frederiksen...	1.0E-92	[1..406]	[1..406]
gi\|77956829, gi\|... - gi\|77956829\|ref\|ZP_00820906.1\| COG1940: Transcriptional regulator/sugar kinase [Yersinia bercovieri ...	3.0E-92	[1..406]	[1..406]
gi\|77961552 - gi\|77961552\|ref\|ZP_00825387.1\| COG1940: Transcriptional regulator/sugar kinase [Yersinia mollaretii ...	3.0E-92	[1..406]	[1..406]
gi\|21957959, gi\|... - gi\|22125103\|ref\|NP_668526.1\| transcriptional repressor of nag (N-acetylglucosamine) operon [Yersinia... gi\|145599891, gi... - gi\|145599891\|ref\|YP_001163967.1\| N-acetylglucosamine regulatory protein [Yersinia pestis Pestoides F... gi\|108774922, gi... - gi\|108811274\|ref\|YP_647041.1\| N-acetylglucosamine regulatory protein [Yersinia pestis Nepal516], gi\|...	4.0E-92	[1..406]	[14..419]
gi\|45440919, gi\|... - gi\|45440919\|ref\|NP_992458.1\| putative N-acetylglucosamine regulatory protein [Yersinia pestis biovar...	5.0E-92	[1..406]	[14..419]

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Predicted Domain #1

Region A:
Residues: [1-406]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPGGQAQIG NVDLVKQLNS AAVYRLIDQH GPISRIQIAE QSQLAPASVT KITRQLIERG  60
   61 LIKEVDQQAS TGGRRAISIV TETRNFHAIG VRLGRHDTTL TLYDLSSKVV AEEHYPLPER 120
  121 TQETLEHALL NTIAVFIDSC QRKIRELIAI SVILPGLVDP ESGVIRYMPH IQVENWGLVE 180
  181 ALEKRFHVTC FVGHDIRSLA LAEHYFGASQ DCEDSILVRV HRGTGAGIIS NGRIFIGRNG 240
  241 NVGEIGHIQV EPLGERCHCG NFGCLETIAA NAAIEQRVLN LLKQGYQSRV PLDDCTIKTI 300
  301 CKAANRGDSL ASEVIEHVGR HLGKTIAIAI NLFNPQKIVI AGEIIEADKV LLPAIESCIN 360
  361 TQALKAFRKN LPVVRSTLDH RSAIGAFALV KRAMLNGTLL QRLLES

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	87.0
Match:	1z05A
Description:	Crystal structure of the ROK family transcriptional regulator, homolog of E.coli MLC protein.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbohydrate kinase activity	0.7849166795124	bayes_pls_golite062009
binding	0.778934303209369	bayes_pls_golite062009
catalytic activity	0.666924658593345	bayes_pls_golite062009
sequence-specific DNA binding	0.53285802828572	bayes_pls_golite062009
transcription regulator activity	0.527726744596866	bayes_pls_golite062009
transcription repressor activity	0.513853050429619	bayes_pls_golite062009
hexokinase activity	0.32024736915472	bayes_pls_golite062009
protein binding	0.238186535482463	bayes_pls_golite062009
nucleic acid binding	0.226676176856305	bayes_pls_golite062009
DNA binding	0.0378796029809374	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: