YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|1788380, gi\|1...
Organism:	Escherichia coli K-12
Length:	231 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1788380, gi|1....

Description	E-value	Query Range	Subject Range
gi\|76611769 - gi\|76611769\|ref\|XP_614178.2\| PREDICTED: similar to uridine-cytidine kinase 2 [Bos taurus]	189.0	[0..13]	[230..224]
gi\|81244853, gi\|... - gi\|82543442\|ref\|YP_407389.1\| uridine/cytidine kinase [Shigella boydii Sb227], gi\|81244853\|gb\|ABB6556...	188.0	[0..1]	[231..1]
tr\|A0A0G3HZ65\|A0... - Uridine kinase OS=Escherichia coli (strain K12) GN=udk PE=3 SV=2 gi\|91072929, gi\|... - gi\|91211355\|ref\|YP_541341.1\| uridine kinase [Escherichia coli UTI89], gi\|91072929\|gb\|ABE07810.1\| uri... gi\|26248441, gi\|... - gi\|26248441\|ref\|NP_754481.1\| uridine kinase [Escherichia coli CFT073], gi\|26108846\|gb\|AAN81049.1\|AE0...	187.0	[0..2]	[231..5]
gi\|238789830, gi... - gi\|77975896\|ref\|ZP_00831430.1\| COG0572: Uridine kinase [Yersinia frederiksenii ATCC 33641], gi\|23878...	184.0	[0..2]	[231..21]
gi\|26350013 - gi\|26350013\|dbj\|BAC38646.1\| unnamed protein product [Mus musculus]	184.0	[0..13]	[230..7]
gi\|46912791, gi\|... - gi\|54308363\|ref\|YP_129383.1\| uridine kinase [Photobacterium profundum SS9], gi\|46912791\|emb\|CAG19581...	183.0	[0..8]	[231..24]
gi\|48425793, gi\|... - gi\|48425800\|pdb\|1UJ2\|B Chain B, Crystal Structure Of Human Uridine-Cytidine Kinase 2 Complexed With ...	183.0	[0..15]	[230..11]
gi\|57753906 - gi\|57753906\|dbj\|BAD86761.1\| uridind kinase [Klebsiella pneumoniae] gi\|238547955, gi... - gi\|238895638\|ref\|YP_002920373.1\| uridine kinase [Klebsiella pneumoniae NTUH-K2044], gi\|238547955\|dbj...	181.0	[0..2]	[231..3]

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Predicted Domain #1

Region A:
Residues: [1-231]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRRPLPNI QVNQVAKYMT DQSHQCVIIG IAGASASGKS LIASTLYREL REQVGDEHIG  60
   61 VIPEDCYYKD QSHLSMEERV KTNYDHPSAM DHSLLLEHLQ ALKRGSAIDL PVYSYVEHTR 120
  121 MKETVTVEPK KVIILEGILL LTDARLRDEL NFSIFVDTPL DICLMRRIKR DVNERGRSMD 180
  181 SVMAQYQKTV RPMFLQFIEP SKQYADIIVP RGGKNRIAID ILKAKISQFF E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.39794
Match:	1udwA
Description:	Crystal structure of human uridine-cytidine kinase 2 complexed with a feedback-inhibitor, CTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleobase, nucleoside, nucleotide kinase activity	2.98849022091298	bayes_pls_golite062009
nucleotide kinase activity	2.24094813695083	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	1.96697952975573	bayes_pls_golite062009
kinase activity	1.34679666271693	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
binding	0.995117091387923	bayes_pls_golite062009
hydrolase activity	0.247702859990584	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: