YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|25300229
Organism:	Yersinia pestis
Length:	311 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25300229.

Description	E-value	Query Range	Subject Range
gi\|89102558 - gi\|89102558\|ref\|ZP_01175182.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia pesti... gi\|51595044, gi\|... - gi\|51595044\|ref\|YP_069235.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersinia ... gi\|77631674, gi\|... - gi\|77631674\|ref\|ZP_00794260.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia pseud... gi\|169752261, gi... - gi\|170025727\|ref\|YP_001722232.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersi... gi\|77633649 - gi\|77633649\|ref\|ZP_00795771.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia pesti... gi\|186697076, gi... - gi\|186894050\|ref\|YP_001871162.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersi...	0.0	[5..311]	[1..307]
gi\|36786947, gi\|... - gi\|37527512\|ref\|NP_930856.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Photorhab...	0.0	[1..310]	[1..310]
gi\|229705991, gi... - gi\|229837048\|ref\|ZP_04457213.1\| UDP-3-O-acyl N-acetylglucosamine deacetylase [Yersinia pestis Pestoi... gi\|161484749 - gi\|161484749\|ref\|NP_670917.2\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersinia... gi\|229840449, gi... - gi\|229840449\|ref\|ZP_04460608.1\| UDP-3-O-acyl N-acetylglucosamine deacetylase [Yersinia pestis biovar... LPXC_YERPS - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Yersinia pseudotuberculosis GN=lpxC ... gi\|161511303 - gi\|161511303\|ref\|NP_994894.2\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersinia... gi\|218927757 - gi\|218927757\|ref\|YP_002345632.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersi... gi\|229689885, gi... - gi\|229843009\|ref\|ZP_04463159.1\| UDP-3-O-acyl N-acetylglucosamine deacetylase [Yersinia pestis biovar... gi\|229682123, gi... - gi\|229900784\|ref\|ZP_04515908.1\| UDP-3-O-acyl N-acetylglucosamine deacetylase [Yersinia pestis Nepal5... LPXC_YERP3 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP... LPXC_YERPE - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Yersinia pestis GN=lpxC PE=3 SV=2 LPXC_YERPS - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Yersinia pseudotuberculosis serotype I (strain IP329...	0.0	[6..311]	[1..306]
gi\|238709370, gi... - gi\|238752437\|ref\|ZP_04613914.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersin... gi\|238700076, gi... - gi\|238761562\|ref\|ZP_04622537.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersin... gi\|238784563, gi... - gi\|77958229\|ref\|ZP_00822266.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia berco... gi\|238718453, gi... - gi\|77962104\|ref\|ZP_00825929.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia molla...	0.0	[6..311]	[1..306]
gi\|238729311, gi... - gi\|77977546\|ref\|ZP_00832991.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia inter...	0.0	[6..311]	[1..306]
gi\|238725096, gi... - gi\|77976094\|ref\|ZP_00831627.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia frede...	0.0	[6..311]	[1..306]
LPXC_PHOLL - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Photorhabdus luminescens subsp. laumondii (strain DS... LPXC_PHOLL - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Photorhabdus luminescens subsp. laum...	0.0	[6..310]	[1..305]
LPXC_SALPC - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella paratyphi C (strain RKS4594) GN=lpxC PE=3... LPXC_SALEP - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella enteritidis PT4 (strain P125109) GN=lpxC ... gi\|197262672, gi... - gi\|197262672\|ref\|ZP_03162746.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmon... LPXC_SALTY - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC... LPXC_SALA4 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella agona (strain SL483) GN=lpxC PE=3 SV=1 LPXC_SALSV - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella schwarzengrund (strain CVM19633) GN=lpxC ... gi\|194459322, gi... - gi\|194472958\|ref\|ZP_03078942.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmon... LPXC_SALCH - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Salmonella choleraesuis GN=lpxC PE=3... LPXC_SALG2 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) G... gi\|204926835, gi... - gi\|204926835\|ref\|ZP_03218037.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmon... gi\|199604886, gi... - gi\|200387788\|ref\|ZP_03214400.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmon... gi\|238911191 - gi\|238911191\|ref\|ZP_04655028.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmon... LPXC_SALDC - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella dublin (strain CT_02021853) GN=lpxC PE=3 ... LPXC_SALTY - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Salmonella typhimurium GN=lpxC PE=3 ... LPXC_SALCH - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella choleraesuis (strain SC-B67) GN=lpxC PE=3... LPXC_SALTY - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Salmonella typhimurium GN=lpxC PE=3 ... LPXC_SALCH - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Salmonella choleraesuis GN=lpxC PE=3... LPXC_SALPB - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Salmonella paratyphi B (strain ATCC ... gi\|168264018, gi... - gi\|205347512\|gb\|EDZ34143.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... gi\|205337563, gi... - gi\|205337563\|gb\|EDZ24327.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... gi\|168234898, gi... - gi\|197291822\|gb\|EDY31172.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... gi\|205334950, gi... - gi\|205334950\|gb\|EDZ21714.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... LPXC_SALHS - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella heidelberg (strain SL476) GN=lpxC PE=3 SV... LPXC_SALNS - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella newport (strain SL254) GN=lpxC PE=3 SV=1 gi\|168820872, gi... - gi\|205342554\|gb\|EDZ29318.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... gi\|168464314, gi... - gi\|195632566\|gb\|EDX51020.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... LPXC_SALPB - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)... gi\|167990007, gi... - gi\|205331399\|gb\|EDZ18163.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... gi\|167550671, gi... - gi\|205324315\|gb\|EDZ12154.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... lcl\|NC_016856.1_... - [gene=lpxC] [protein=UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase] [protein_id=YP_00...	0.0	[6..310]	[1..305]
gi\|75226681 - gi\|75226681\|ref\|ZP_00713661.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Escherichia co... gi\|75255003 - gi\|75255003\|ref\|ZP_00726926.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Escherichia co... LPXC_ECO24 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN... LPXC_ECOHS - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli O9:H4 (strain HS) GN=lpxC PE=3 SV=1 LPXC_SHISS - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Shigella sonnei (strain Ss046) GN=lpxC PE=3 SV=1 LPXC_SHIDS - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=lp... LPXC_ECOL5 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=l... LPXC_SHIFL - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Shigella flexneri GN=lpxC PE=3 SV=1 LPXC_SHIF8 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Shigella flexneri serotype 5b (strain 8401) GN=lpxC ... gi\|24111541, gi\|... - gi\|24111541\|ref\|NP_706051.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Shigella ... LPXC_ECOL6 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 ... gi\|30061663, gi\|... - gi\|30061663\|ref\|NP_835834.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Shigella ... LPXC_ECO57 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli O157:H7 GN=lpxC PE=3 SV=1 gi\|21321977, gi\|... - gi\|89106979\|ref\|AP_000759.1\| UDP-3-O-acyl N-acetylglucosamine deacetylase [Escherichia coli str. K-1... EG10265 - UDP-3-O-acyl N-acetylglucosamine deacetylase / Lipid A synthesis, UDP-3-O-(R-3-hydroxymyristoyl)-N-a... LPXC_ECOUT - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli (strain UTI89 / UPEC) GN=lpxC PE=3 ... gi\|15799780, gi\|... - gi\|15799780\|ref\|NP_285792.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escherich... gi\|15829354, gi\|... - gi\|15829354\|ref\|NP_308127.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escherich... LPXC_ECOLC - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Croo... gi\|254791233, gi... - gi\|254791233\|ref\|YP_003076070.1\| UDP-3-O-acyl N-acetylglucosamine deacetylase [Escherichia coli O157... gi\|254160218, gi... - gi\|254160218\|ref\|YP_003043326.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Esche... gi\|226840617, gi... - gi\|254037511\|ref\|ZP_04871588.1\| UDP-3-O-acyl N-acetylglucosamine deacetylase [Escherichia sp. 1_1_43... gi\|253325918, gi... - gi\|254287021\|ref\|YP_003052769.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Esche... gi\|251783659, gi... - gi\|251783659\|ref\|YP_002997963.1\| hypothetical protein B21_00096 [Escherichia coli BL21], gi\|24237593... LPXC_ECOBW - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=l... LPXC_ECOLI - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (EC 3.5.1.-) (UDP-3-O-acyl-GlcNAc deace... gi\|237704245, gi... - gi\|237704245\|ref\|ZP_04534726.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escher... gi\|227884999, gi... - gi\|227884999\|ref\|ZP_04002804.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escher... LPXC_ECOK1 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli O1:K1 / APEC GN=lpxC PE=3 SV=1 gi\|124532674, gi... - gi\|124532674\|ref\|ZP_01702277.1\| UDP-3-0-acyl N-acetylglucosamine deacetylase [Escherichia coli B], g... sp\|B7UIE6\|LPXC_ECO27 - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Escherichia coli O127:H6 (strain E23... LPXC_ECOL6 - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Escherichia coli O6 GN=lpxC PE=3 SV=... gi\|168755704, gi... - gi\|189357023\|gb\|EDU75442.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escherichi... gi\|189359893, gi... - gi\|189359893\|gb\|EDU78312.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escherichi... gi\|189000444, gi... - gi\|189000444\|gb\|EDU69430.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escherichi... gi\|168789623, gi... - gi\|189370802\|gb\|EDU89218.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escherichi... LPXC_ECODH - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli (strain K12 / DH10B) GN=lpxC PE=3 S... LPXC_ECO27 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN... EG10265 - UDP-3-O-acyl N-acetylglucosamine deacetylase / Lipid A synthesis, UDP-3-O-(R-3-hydroxymyristoyl)-N-a... gi\|217325812, gi... - gi\|217325812\|ref\|ZP_03441896.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escher... LPXC_ECO8A - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli O8 (strain IAI1) GN=lpxC PE=3 SV=1 LPXC_ECO81 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli O81 (strain ED1a) GN=lpxC PE=3 SV=1 LPXC_ECO55 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli (strain 55989 / EAEC) GN=lpxC PE=3 ... LPXC_ECO7I - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=lpx... LPXC_ECOLU - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)... LPXC_ECOSM - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=lpxC PE... gi\|188490855, gi... - gi\|188495656\|ref\|ZP_03002926.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escher... gi\|195938223 - gi\|195938223\|ref\|ZP_03083605.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escher... gi\|208728731, gi... - gi\|208808930\|ref\|ZP_03251267.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escher... gi\|208813525, gi... - gi\|208813525\|ref\|ZP_03254854.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escher... gi\|208740794, gi... - gi\|208820671\|ref\|ZP_03260991.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escher... LPXC_ECO5E - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=l... LPXC_ECOSE - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Escherichia coli (strain SE11) GN=lpxC PE=3 SV=1	0.0	[6..310]	[1..305]
LPXC_SHIBS - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Shigella boydii serotype 4 (strain Sb227) GN=lpxC PE...	0.0	[6..310]	[1..305]

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Predicted Domain #1

Region A:
Residues: [1-311]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRDKMMIKQR TLKRIVQATG VGLHTGKKVT LTMRPAPANT GVIYRRTDLN PPVDFPADAK  60
   61 SVRDTMLCTC LVNEHDVRIS TVEHLNAALA GLGIDNIIIE VNAPEVPIMD GSASPFVYLL 120
  121 LDAGIEELNS AKKFLRLKET VRVEDGDKWA ELSPFNGFRL DFTIDFNHPA IDSSTQRYCL 180
  181 DFSADSFVRQ ISRARTFGFM RDIEYLQSRG LCLGGSFDCA IVVDDYRVLN EDGLRFEDEF 240
  241 VRHKMLDAIG DLFMCGHNII GAFTAYKSGH ALNNKLLQAV LAKQEAWEFV TFQDEAEMPL 300
  301 AFKAPSTVLA Y

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	85.0
Match:	1xxeA
Description:	RDC refined solution structure of the AaLpxC/TU-514 complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity	3.46483388226683	bayes_pls_golite062009
catalytic activity	1.24889475603062	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: