YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7441929
Organism:	Plasmodium falciparum
Length:	328 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7441929.

Description	E-value	Query Range	Subject Range
gi\|53612269, gi\|... - gi\|67158732\|ref\|ZP_00419593.1\| DnaJ central domain (CXXCXGXG):Heat shock protein DnaJ, N-terminal:Ch... DNAJ_AZOVD - Chaperone protein DnaJ OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=dnaJ PE=3 SV=1	315.0	[0..2]	[326..3]
gi\|107103857 - gi\|107103857\|ref\|ZP_01367775.1\| hypothetical protein PaerPA_01004928 [Pseudomonas aeruginosa PACS2] DNAJ_PSEA8 - Chaperone protein DnaJ OS=Pseudomonas aeruginosa (strain LESB58) GN=dnaJ PE=3 SV=1 DNAJ_PSEAE - Chaperone protein dnaJ OS=Pseudomonas aeruginosa GN=dnaJ PE=3 SV=1 DNAJ_PSEAB - Chaperone protein DnaJ OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=dnaJ PE=3 SV=1 DNAJ_PSEAE - Chaperone protein DnaJ OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 1222... gi\|194549490, gi... - gi\|84317360\|ref\|ZP_00965808.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|126197717, gi... - gi\|84323584\|ref\|ZP_00971653.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom...	310.0	[0..2]	[326..3]
gi\|33578041 - gi\|33578041\|gb\|AAQ22347.1\| heat shock protein [Pseudomonas stutzeri A15] tr\|F8GZK8\|F8GZK8... - Chaperone protein DnaJ OS=Pseudomonas stutzeri (strain ATCC 17588 / DSM 5190 / CCUG 11256 / JCM 5965... DNAJ_PSEST - Chaperone protein DnaJ OS=Pseudomonas stutzeri GN=dnaJ PE=3 SV=1 tr\|F2N4J3\|F2N4J3... - Chaperone protein DnaJ OS=Pseudomonas stutzeri (strain DSM 4166 / CMT.9.A) GN=dnaJ PE=3 SV=1	310.0	[0..2]	[324..3]
DNAJ_RHIME - Chaperone protein DnaJ OS=Rhizobium meliloti (strain 1021) GN=dnaJ PE=3 SV=1 DNAJ_RHIME - Chaperone protein dnaJ OS=Rhizobium meliloti GN=dnaJ PE=3 SV=1	308.0	[0..1]	[327..1]
DNAJ_PSEPK - Chaperone protein DnaJ OS=Pseudomonas putida (strain KT2440) GN=dnaJ PE=3 SV=1 tr\|E4R635\|E4R635... - Chaperone protein DnaJ OS=Pseudomonas putida (strain BIRD-1) GN=dnaJ PE=3 SV=1	308.0	[0..2]	[326..3]
DNAJ_SINMW - Chaperone protein DnaJ OS=Sinorhizobium medicae (strain WSM419) GN=dnaJ PE=3 SV=1	308.0	[0..1]	[327..1]
DNAJ_RHIRD - Chaperone protein DnaJ OS=Rhizobium radiobacter GN=dnaJ PE=1 SV=1	308.0	[0..1]	[327..1]
DNAJ_RHOS5 - Chaperone protein DnaJ OS=Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) GN=dnaJ PE=3 SV=1	307.0	[0..2]	[327..3]
DNAJ_BRUSU - Chaperone protein DnaJ OS=Brucella suis biovar 1 (strain 1330) GN=dnaJ PE=3 SV=1 DNAJ_BRUME - Chaperone protein DnaJ OS=Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) GN=dn... DNAJ_BRUMB - Chaperone protein DnaJ OS=Brucella melitensis biotype 2 (strain ATCC 23457) GN=dnaJ PE=3 SV=1 gi\|225618155, gi... - gi\|225626498\|ref\|ZP_03784537.1\| chaperone protein DnaJ [Brucella ceti str. Cudo], gi\|225618155\|gb\|EE... gi\|254705131 - gi\|254705131\|ref\|ZP_05166959.1\| chaperone protein DnaJ [Brucella suis bv. 3 str. 686] DNAJ_BRUSU - Chaperone protein dnaJ OS=Brucella suis GN=dnaJ PE=3 SV=1 gi\|254700759 - gi\|254700759\|ref\|ZP_05162587.1\| chaperone protein DnaJ [Brucella suis bv. 5 str. 513] gi\|254709104 - gi\|254709104\|ref\|ZP_05170915.1\| chaperone protein DnaJ [Brucella pinnipedialis B2/94] DNAJ_BRUME - Chaperone protein dnaJ OS=Brucella melitensis GN=dnaJ PE=3 SV=1 gi\|254707354 - gi\|254707354\|ref\|ZP_05169182.1\| chaperone protein DnaJ [Brucella pinnipedialis M163/99/10] gi\|254718169 - gi\|254718169\|ref\|ZP_05179980.1\| chaperone protein DnaJ [Brucella sp. 83/13] DNAJ_BRUSI - Chaperone protein DnaJ OS=Brucella suis (strain ATCC 23445 / NCTC 10510) GN=dnaJ PE=3 SV=1 DNAJ_BRUC2 - Chaperone protein DnaJ OS=Brucella canis (strain ATCC 23365 / NCTC 10854) GN=dnaJ PE=3 SV=1	307.0	[0..1]	[327..1]
DNAJ_AGRFC - Chaperone protein DnaJ OS=Agrobacterium fabrum (strain C58 / ATCC 33970) GN=dnaJ PE=2 SV=2 gi\|25296037, gi\|... - pir\|\|AD2591 molecular chaperone, DnaJ family dnaJ [imported] - Agrobacterium tumefaciens (strain C58...	307.0	[0..1]	[327..1]

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Predicted Domain #1

Region A:
Residues: [1-138]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKDYYSILG VSRDCTTNDL KKAYRKLAMM WHPDKHNDEK SKKEAEEKFK NIAEAYDVLA  60
   61 DEEKRKIYDT YGEEGLKGSI PTGGNTYVYS GVDPSELFSR IFGSDGQFSF TSTFDEDFSP 120
  121 FSTFVNMTSR KSRPSTTT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.09691
Match:	1bq0A
Description:	J-DOMAIN (RESIDUES 1-77) OF THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 1-104) OF THE MOLECULAR CHAPERONE DNAJ, NMR, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
unfolded protein binding	5.16965422989143	bayes_pls_golite062009
binding	2.63138872417193	bayes_pls_golite062009
heat shock protein binding	2.17994194200939	bayes_pls_golite062009
chaperone binding	1.61155546076854	bayes_pls_golite062009
protein binding	1.60937254813642	bayes_pls_golite062009
nucleic acid binding	1.01835792943261	bayes_pls_golite062009
transcription regulator activity	0.972380300832732	bayes_pls_golite062009
DNA binding	0.72916846057707	bayes_pls_golite062009
Hsp70 protein binding	0.541755903922701	bayes_pls_golite062009
transporter activity	0.156214544805643	bayes_pls_golite062009
catalytic activity	0.106988907594358	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [139-328]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NINTNNYNKP ATYEVPLSLS LEELYSGCKK KLKITRKRFM GTKSYEDDNY VTIDVKAGWK  60
   61 DGTKITFYGE GDQLSPMAQP GDLVFKVKTK THDRFLRDAN HLIYKCPVPL DKALTGFQFI 120
  121 VKSLDNRDIN VRVDDIVTPK SRKIVAKEGM PSSKYPSMKG DLIVEFDIVF PKSLTSEKKK 180
  181 IIRETLANTF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.09691
Match:	2q2gA
Description:	No description for 2q2gA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: