YRC Public Data Repository - Protein Structure Prediction

Protein:	LPXC_SHIFL
Organism:	Shigella flexneri
Length:	305 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LPXC_SHIFL.

Description	E-value	Query Range	Subject Range
gi\|150260404, gi... - gi\|150260404\|ref\|ZP_01917132.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersin... gi\|145600336, gi... - gi\|145600336\|ref\|YP_001164412.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersi... gi\|167426450, gi... - gi\|167426450\|ref\|ZP_02318203.1\| UDP-3-0-acyl N-acetylglucosamine deacetylase [Yersinia pestis biovar... gi\|167421900, gi... - gi\|167421900\|ref\|ZP_02313653.1\| UDP-3-0-acyl N-acetylglucosamine deacetylase [Yersinia pestis biovar... gi\|22127494, gi\|... - gi\|22127494\|ref\|NP_670917.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersinia ... gi\|25300229 - gi\|25300229\|pir\|\|AF0069 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (EC 3.5.1.-) [i... gi\|115346368, gi... - gi\|16120889\|ref\|NP_404202.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersinia ... gi\|108810592, gi... - gi\|108810592\|ref\|YP_646359.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersinia... gi\|45438224, gi\|... - gi\|45443355\|ref\|NP_994894.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersinia ... gi\|108809531, gi... - gi\|108809531\|ref\|YP_653447.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersinia... gi\|165928192, gi... - gi\|165928192\|ref\|ZP_02224024.1\| UDP-3-0-acyl N-acetylglucosamine deacetylase [Yersinia pestis biovar... gi\|162419483, gi... - gi\|162419483\|ref\|YP_001607290.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersi... gi\|167401283, gi... - gi\|167401283\|ref\|ZP_02306783.1\| UDP-3-0-acyl N-acetylglucosamine deacetylase [Yersinia pestis biovar... gi\|166211861, gi... - gi\|166211861\|ref\|ZP_02237896.1\| UDP-3-0-acyl N-acetylglucosamine deacetylase [Yersinia pestis biovar... gi\|166008906, gi... - gi\|166008906\|ref\|ZP_02229804.1\| UDP-3-0-acyl N-acetylglucosamine deacetylase [Yersinia pestis biovar... gi\|165914225, gi... - gi\|165937813\|ref\|ZP_02226374.1\| UDP-3-0-acyl N-acetylglucosamine deacetylase [Yersinia pestis biovar...	534.0	[0..1]	[305..6]
gi\|89102558 - gi\|89102558\|ref\|ZP_01175182.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia pesti... gi\|51595044, gi\|... - gi\|51595044\|ref\|YP_069235.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersinia ... gi\|77631674, gi\|... - gi\|77631674\|ref\|ZP_00794260.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia pseud... gi\|169752261, gi... - gi\|170025727\|ref\|YP_001722232.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersi... gi\|77633649 - gi\|77633649\|ref\|ZP_00795771.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia pesti... gi\|186697076, gi... - gi\|186894050\|ref\|YP_001871162.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersi...	534.0	[0..1]	[305..2]
gi\|238709370, gi... - gi\|238752437\|ref\|ZP_04613914.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersin... gi\|238700076, gi... - gi\|238761562\|ref\|ZP_04622537.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersin... gi\|238784563, gi... - gi\|77958229\|ref\|ZP_00822266.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia berco... gi\|238718453, gi... - gi\|77962104\|ref\|ZP_00825929.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia molla...	534.0	[0..1]	[305..1]
gi\|229705991, gi... - gi\|229837048\|ref\|ZP_04457213.1\| UDP-3-O-acyl N-acetylglucosamine deacetylase [Yersinia pestis Pestoi... gi\|161484749 - gi\|161484749\|ref\|NP_670917.2\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersinia... gi\|229840449, gi... - gi\|229840449\|ref\|ZP_04460608.1\| UDP-3-O-acyl N-acetylglucosamine deacetylase [Yersinia pestis biovar... LPXC_YERPS - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Yersinia pseudotuberculosis GN=lpxC ... gi\|161511303 - gi\|161511303\|ref\|NP_994894.2\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersinia... gi\|218927757 - gi\|218927757\|ref\|YP_002345632.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Yersi... gi\|229689885, gi... - gi\|229843009\|ref\|ZP_04463159.1\| UDP-3-O-acyl N-acetylglucosamine deacetylase [Yersinia pestis biovar... gi\|229682123, gi... - gi\|229900784\|ref\|ZP_04515908.1\| UDP-3-O-acyl N-acetylglucosamine deacetylase [Yersinia pestis Nepal5... LPXC_YERP3 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP... LPXC_YERPE - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Yersinia pestis GN=lpxC PE=3 SV=2 LPXC_YERPS - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Yersinia pseudotuberculosis serotype I (strain IP329...	534.0	[0..1]	[305..1]
LPXC_SHIBS - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Shigella boydii serotype 4 (strain Sb227) GN=lpxC PE...	533.0	[0..1]	[305..1]
gi\|238729311, gi... - gi\|77977546\|ref\|ZP_00832991.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia inter...	532.0	[0..1]	[305..1]
gi\|238725096, gi... - gi\|77976094\|ref\|ZP_00831627.1\| COG0774: UDP-3-O-acyl-N-acetylglucosamine deacetylase [Yersinia frede...	532.0	[0..1]	[305..1]
gi\|36786947, gi\|... - gi\|37527512\|ref\|NP_930856.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Photorhab...	531.0	[0..1]	[305..6]
LPXC_PHOLL - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Photorhabdus luminescens subsp. laumondii (strain DS... LPXC_PHOLL - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Photorhabdus luminescens subsp. laum...	531.0	[0..1]	[305..1]
LPXC_SALPC - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella paratyphi C (strain RKS4594) GN=lpxC PE=3... LPXC_SALEP - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella enteritidis PT4 (strain P125109) GN=lpxC ... gi\|197262672, gi... - gi\|197262672\|ref\|ZP_03162746.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmon... LPXC_SALTY - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC... LPXC_SALA4 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella agona (strain SL483) GN=lpxC PE=3 SV=1 LPXC_SALSV - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella schwarzengrund (strain CVM19633) GN=lpxC ... gi\|194459322, gi... - gi\|194472958\|ref\|ZP_03078942.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmon... LPXC_SALCH - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Salmonella choleraesuis GN=lpxC PE=3... LPXC_SALG2 - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) G... gi\|204926835, gi... - gi\|204926835\|ref\|ZP_03218037.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmon... gi\|199604886, gi... - gi\|200387788\|ref\|ZP_03214400.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmon... gi\|238911191 - gi\|238911191\|ref\|ZP_04655028.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmon... LPXC_SALDC - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella dublin (strain CT_02021853) GN=lpxC PE=3 ... LPXC_SALTY - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Salmonella typhimurium GN=lpxC PE=3 ... LPXC_SALCH - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella choleraesuis (strain SC-B67) GN=lpxC PE=3... LPXC_SALTY - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Salmonella typhimurium GN=lpxC PE=3 ... LPXC_SALCH - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Salmonella choleraesuis GN=lpxC PE=3... LPXC_SALPB - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase OS=Salmonella paratyphi B (strain ATCC ... gi\|168264018, gi... - gi\|205347512\|gb\|EDZ34143.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... gi\|205337563, gi... - gi\|205337563\|gb\|EDZ24327.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... gi\|168234898, gi... - gi\|197291822\|gb\|EDY31172.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... gi\|205334950, gi... - gi\|205334950\|gb\|EDZ21714.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... LPXC_SALHS - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella heidelberg (strain SL476) GN=lpxC PE=3 SV... LPXC_SALNS - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella newport (strain SL254) GN=lpxC PE=3 SV=1 gi\|168820872, gi... - gi\|205342554\|gb\|EDZ29318.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... gi\|168464314, gi... - gi\|195632566\|gb\|EDX51020.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... LPXC_SALPB - UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)... gi\|167990007, gi... - gi\|205331399\|gb\|EDZ18163.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... gi\|167550671, gi... - gi\|205324315\|gb\|EDZ12154.1\| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Salmonella... lcl\|NC_016856.1_... - [gene=lpxC] [protein=UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase] [protein_id=YP_00...	530.0	[0..1]	[305..1]

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Predicted Domain #1

Region A:
Residues: [1-305]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKQRTLKRI VQATGVGLHT GKKVTLTLRP APANTGVIYR RTDLNPPVDF PADAKSVRDT  60
   61 MLCTCLVNEH DVRISTVEHL NAALAGLGID NIVIEVNAPE IPIMDGSAAP FVYLLLDAGI 120
  121 DELNCAKKFV RIKETVRVED GDKWAEFKPY NGFSLDFTID FNHPAIDSSN QRYAMNFSAD 180
  181 AFMRQISRAR TFGFMRDIEY LQSRGLCLGG SFDCAIVVDD YRVLNEDGLR FEDEFVRHKM 240
  241 LDAIGDLFMC GHNIIGAFTA YKSGHALNNK LLQAVLAKQE AWEYVTFQDD AELPLAFKAP 300
  301 SAVLA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.221849
Match:	1xxeA
Description:	RDC refined solution structure of the AaLpxC/TU-514 complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity	3.46483388226683	bayes_pls_golite062009
catalytic activity	1.24889475603062	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: