YRC Public Data Repository - Protein Structure Prediction

Protein:	GCS2_CUPMC
Organism:	Cupriavidus metallidurans CH34
Length:	372 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCS2_CUPMC.

Description	E-value	Query Range	Subject Range
GCS2_BURXL - Putative glutamate--cysteine ligase 2 OS=Burkholderia xenovorans (strain LB400) GN=Bxeno_A4387 PE=3 ...	348.0	[0..1]	[371..1]
gi\|84363383 - gi\|84363383\|ref\|ZP_00987971.1\| COG2170: Uncharacterized conserved protein [Burkholderia dolosa AUO15...	346.0	[0..1]	[371..1]
GCS2_BURA4 - Putative glutamate--cysteine ligase 2 OS=Burkholderia ambifaria (strain MC40-6) GN=BamMC406_0068 PE=... GCS2_BURCM - Putative glutamate--cysteine ligase 2 OS=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) GN=Bamb... gi\|171095974, gi... - gi\|171318833\|ref\|ZP_02907970.1\| glutamate--cysteine ligase GCS2 [Burkholderia ambifaria MEX-5], gi\|1... gi\|170136067, gi... - gi\|170699031\|ref\|ZP_02890088.1\| glutamate--cysteine ligase GCS2 [Burkholderia ambifaria IOP40-10], g...	344.0	[0..1]	[371..1]
GCS2_BURCC - Putative glutamate--cysteine ligase 2 OS=Burkholderia cenocepacia (strain MC0-3) GN=Bcenmc03_0087 PE... GCS2_BURCJ - Putative glutamate--cysteine ligase 2 OS=Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 /... GCS2_BURCA - Putative glutamate--cysteine ligase 2 OS=Burkholderia cenocepacia (strain AU 1054) GN=Bcen_0001 PE=3... gi\|84356372 - gi\|84356372\|ref\|ZP_00981220.1\| COG2170: Uncharacterized conserved protein [Burkholderia cenocepacia ... GCS2_BURCH - Putative glutamate--cysteine ligase 2 OS=Burkholderia cenocepacia (strain HI2424) GN=Bcen2424_0069 P...	343.0	[0..1]	[371..1]
gi\|167921112 - gi\|167921112\|ref\|ZP_02508203.1\| carboxylate-amine ligase [Burkholderia pseudomallei BCC215] gi\|254174738, gi... - gi\|254174738\|ref\|ZP_04881399.1\| carboxylate-amine ligase family protein [Burkholderia mallei ATCC 10... gi\|167904894 - gi\|167904894\|ref\|ZP_02492099.1\| carboxylate-amine ligase [Burkholderia pseudomallei NCTC 13177] gi\|167913174 - gi\|167913174\|ref\|ZP_02500265.1\| carboxylate-amine ligase [Burkholderia pseudomallei 112] gi\|217424014, gi... - gi\|217424014\|ref\|ZP_03455514.1\| carboxylate-amine ligase family protein [Burkholderia pseudomallei 5... gi\|167721871 - gi\|167721871\|ref\|ZP_02405107.1\| carboxylate-amine ligase [Burkholderia pseudomallei DM98] gi\|167740840 - gi\|167740840\|ref\|ZP_02413614.1\| carboxylate-amine ligase [Burkholderia pseudomallei 14] gi\|167001297, gi... - gi\|243062914\|gb\|EES45100.1\| carboxylate-amine ligase family protein [Burkholderia mallei PRL-20], gi... gi\|167847936 - gi\|167847936\|ref\|ZP_02473444.1\| carboxylate-amine ligase [Burkholderia pseudomallei B7210] gi\|167896494 - gi\|167896494\|ref\|ZP_02483896.1\| carboxylate-amine ligase [Burkholderia pseudomallei 7894] gi\|167818055 - gi\|167818055\|ref\|ZP_02449735.1\| carboxylate-amine ligase [Burkholderia pseudomallei 91] gi\|167826420 - gi\|167826420\|ref\|ZP_02457891.1\| carboxylate-amine ligase [Burkholderia pseudomallei 9] GCS2_BURP1 - Putative glutamate--cysteine ligase 2 OS=Burkholderia pseudomallei (strain 1710b) GN=BURPS1710b_0214... GCS2_BURPS - Putative glutamate--cysteine ligase 2 OS=Burkholderia pseudomallei (strain K96243) GN=BPSL0001 PE=3 ... GCS2_BURM9 - Putative glutamate--cysteine ligase 2 OS=Burkholderia mallei (strain NCTC 10229) GN=BMA10229_A1626 P... GCS2_BURMA - Putative glutamate--cysteine ligase 2 OS=Burkholderia mallei (strain ATCC 23344) GN=BMA2917 PE=3 SV=... CAAL_BURMA - Carboxylate-amine ligase BMA2917 OS=Burkholderia mallei GN=BMA2917 PE=3 SV=1 gi\|85065956 - gi\|85065956\|ref\|ZP_01026809.1\| COG2170: Uncharacterized conserved protein [Burkholderia mallei 10229... gi\|148026455, gi... - gi\|87316705\|ref\|ZP_01097719.1\| COG2170: Uncharacterized conserved protein [Burkholderia mallei 20027... gi\|157934215, gi... - gi\|67755079\|ref\|ZP_00493978.1\| COG2170: Uncharacterized conserved protein [Burkholderia pseudomallei... gi\|100122536, gi... - gi\|67760093\|ref\|ZP_00498819.1\| COG2170: Uncharacterized conserved protein [Burkholderia pseudomallei... CAAL_BURPS - Carboxylate-amine ligase BPSL0001 OS=Burkholderia pseudomallei GN=BPSL0001 PE=3 SV=1 gi\|238524300, gi... - gi\|67643056\|ref\|ZP_00441805.1\| carboxylate-amine ligase YbdK [Burkholderia mallei GB8 horse 4], gi\|2... gi\|226193306, gi... - gi\|226193306\|ref\|ZP_03788916.1\| carboxylate-amine ligase family protein [Burkholderia pseudomallei P... GCS2_BURM7 - Putative glutamate--cysteine ligase 2 OS=Burkholderia mallei (strain NCTC 10247) GN=BMA10247_2975 PE... gi\|67637400, gi\|... - gi\|67637400\|ref\|ZP_00436340.1\| COG2170: Uncharacterized conserved protein [Burkholderia mallei 10399... gi\|254201498, gi... - gi\|83621194\|ref\|ZP_00931605.1\| COG2170: Uncharacterized conserved protein [Burkholderia mallei FMH],... gi\|237814391, gi... - gi\|237814391\|ref\|YP_002898842.1\| carboxylate-amine ligase _2975 [Burkholderia pseudomallei MSHR346],... GCS2_BURP6 - Putative glutamate--cysteine ligase 2 OS=Burkholderia pseudomallei (strain 668) GN=BURPS668_0001 PE=... GCS2_BURMS - Putative glutamate--cysteine ligase 2 OS=Burkholderia mallei (strain SAVP1) GN=BMASAVP1_A3394 PE=3 S... gi\|67673934, gi\|... - gi\|99913426\|ref\|ZP_01320075.1\| hypothetical protein Bpse1_03000594 [Burkholderia pseudomallei 1655],... gi\|67681962, gi\|... - gi\|90291181\|ref\|ZP_01210814.1\| hypothetical protein Bpse17_02004166 [Burkholderia pseudomallei 1710a... gi\|254206837, gi... - gi\|83624016\|ref\|ZP_00934272.1\| COG2170: Uncharacterized conserved protein [Burkholderia mallei JHU],... gi\|157808592, gi... - gi\|83679122\|ref\|ZP_00940839.1\| COG2170: Uncharacterized conserved protein [Burkholderia pseudomallei... GCS2_BURP0 - Putative glutamate--cysteine ligase 2 OS=Burkholderia pseudomallei (strain 1106a) GN=BURPS1106A_0001... gi\|161359638, gi... - gi\|90662094\|ref\|ZP_01249930.1\| hypothetical protein Bpse110_02006071 [Burkholderia pseudomallei 1106... gi\|134281344, gi... - gi\|134281344\|ref\|ZP_01768052.1\| carboxylate-amine ligase family protein [Burkholderia pseudomallei 3...	342.0	[0..1]	[371..1]
CAAL_BURS3 - Carboxylate-amine ligase Bcep18194_A3250 OS=Burkholderia sp. (strain 383) GN=Bcep18194_A3250 PE=3 SV... GCS2_BURL3 - Putative glutamate--cysteine ligase 2 OS=Burkholderia lata (strain ATCC 17760 / LMG 22485 / NCIMB 90...	341.0	[0..1]	[371..1]
gi\|76578356, gi\|... - gi\|76808903\|ref\|YP_331630.1\| carboxylate-amine ligase [Burkholderia pseudomallei 1710b], gi\|76578356...	337.0	[0..1]	[371..45]
GCS2_POLSJ - Putative glutamate--cysteine ligase 2 OS=Polaromonas sp. (strain JS666 / ATCC BAA-500) GN=Bpro_4470 ...	336.0	[0..1]	[372..1]
GCS2_CUPPJ - Putative glutamate--cysteine ligase 2 OS=Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) GN=R...	336.0	[0..1]	[371..1]
GCS2_MYCSS - Putative glutamate--cysteine ligase 2 OS=Mycobacterium sp. (strain MCS) GN=Mmcs_0573 PE=3 SV=1 GCS21_MYCSK - Putative glutamate--cysteine ligase 2-1 OS=Mycobacterium sp. (strain KMS) GN=Mkms_0585 PE=3 SV=1	335.0	[0..2]	[370..8]

Back

Predicted Domain #1

Region A:
Residues: [1-372]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLEPFKHSE ALTFGVELEL QLVNRHDYDL APFAPDLLRA LRGTQHAGDI KPEISPSMIE  60
   61 ISTGICHDYA QALEELSVMR DLMVNASRGL NLGICGGGTH PFQVWSDRTI SDSPRYQYIS 120
  121 ELYGYLAKQF TVFGQHVHIG CPSPDESLFL LHAIGRYVPH FIALAASSPY VQGVDTGFAS 180
  181 ARLNSVAAFP MSGRAPFVLT WDAFKAYFDK MRATGVIESM KDFYWDIRPK PEFGTIEVRV 240
  241 MDTPLTVQRA CDIAAYIQAL ARYLLLSRPF MPQEDDYLVY TFNRFQACRF GLEGEYVHPN 300
  301 ELTRMPIADH ILSICDALEP HAEALGSLEA LSNIRALAAS RSNDAHWVRA ANRDAHSLRD 360
  361 MVRQTCEQWG GG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	90.30103
Match:	1r8gA
Description:	Structure and function of YbdK
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.2	NCBI nr	03/2009
PSI-BLAST	2.2.22	FFAS	ffas03
PDB	10/2008	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits