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View Structure Prediction Details

Protein: nas-36
Organism: Caenorhabditis elegans
Length: 617 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-36.

Description E-value Query
Range
Subject
Range
gi|157744633 - gi|157744633|ref|XP_001667413.1| Hypothetical protein CBG11886 [Caenorhabditis briggsae AF16]
NAS36_CAEBR - Zinc metalloproteinase nas-36 OS=Caenorhabditis briggsae GN=nas-36 PE=3 SV=1
336.0 [0..1] [617..1]

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Predicted Domain #1
Region A:
Residues: [1-74]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLCHSIILF NSLISISICS KADDPALLVA SEFKEHFNVE EKQLETVEEL LIKMKKLAHS  60
   61 RSFKGREFGH DAVE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [75-324]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSKKEVAIST QQGTINKKVS PFLFEGDIFL SRRQAVDILK ALSKDKTKRL RRSFVSDKTA  60
   61 TWKTMPIKYR FHESIDFYTI SQIIAAIRFW EDSTCITFEN VSDSPDGDYI EFFSGQGCYS 120
  121 MIGRNGGRQG ISIGESCVKM GVIEHEIGHA LGLWHEQSRP DALGYVTIER DFILPSYISD 180
  181 FLQRDDEIDT LGIPYDLGSV MHYGSTAFSV DQKSKTVVTR DSLYQQTIGQ REKLSFYDVA 240
  241 TINTAYCKDE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.0
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.87713655504947 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.50720289959102 bayes_pls_golite062009
metallopeptidase activity 2.55317823694462 bayes_pls_golite062009
endopeptidase activity 2.52973705827479 bayes_pls_golite062009
hydrolase activity 2.30803642767787 bayes_pls_golite062009
metalloendopeptidase activity 1.81132179546381 bayes_pls_golite062009
catalytic activity 1.26162753036584 bayes_pls_golite062009
exopeptidase activity 0.71491631246151 bayes_pls_golite062009
binding 0.210557818016724 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [325-617]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CKSEKTKCEN GGYMRPSKCS ECLCPDGLGG EKCEKNEDSK NAECGGIIKL TEEWKEIESP  60
   61 NYPDPGYEAD QKCSWLLKAE KGKRVEIEFI EDFSFLCTST CVDFVELKIS DDLRNTGFRF 120
  121 CCYDKPEISF VSQTDTAIII FRSQLSTDIG FKIQAKSTDA EPRTTIAPTI ITTTLAPITV 180
  181 DAPNVWADWG EWSMCSRTCG GCGIRSRVRS CRSKKCEGRR QEFGTCNLKA CPVDKHCAKL 240
  241 LSNNRLCNGK VCTKNDIAIS SCDAPQCCPP FINVDGVCQS DQENQHDELW LSI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.09691
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle