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View Structure Prediction Details

Protein: Alr-PA
Organism: Drosophila melanogaster
Length: 261 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Alr-PA.

Description E-value Query
Range
Subject
Range
gi|220947962 - gi|220947962|gb|ACL86524.1| CG12534-PA [synthetic construct]
gi|24643392, gi|... - gi|24643392|ref|NP_608353.1| CG12534-PA [Drosophila melanogaster], gi|22832612|gb|AAF49017.2| CG1253...
262.0 [0..69] [261..1]
gi|125981799, gi... - gi|54643215|gb|EAL31959.1| GA11683-PA [Drosophila pseudoobscura], gi|125981799|ref|XP_001354903.1| G...
261.0 [0..1] [261..1]
gi|39961850, gi|... - gi|39961850|ref|XP_364723.1| hypothetical protein MG09568.4 [Magnaporthe grisea 70-15], gb|EAA53818....
242.0 [0..69] [259..1]
gi|28921166, gi|... - gi|32421457|ref|XP_331172.1| hypothetical protein [Neurospora crassa], gi|28921166|gb|EAA30480.1| au...
gi|85093549 - gi|85093549|ref|XP_959716.1| augmenter of liver regeneration [Neurospora crassa OR74A]
223.0 [0..72] [261..7]
gi|151943312 - gi|151943312|gb|EDN61625.1| sulfhydryl oxidase [Saccharomyces cerevisiae YJM789]
ERV1 - Flavin-linked sulfhydryl oxidase of the mitochondrial intermembrane space (IMS), oxidizes Mia40p as ...
gi|190406945 - gi|190406945|gb|EDV10212.1| sulfhydryl oxidase [Saccharomyces cerevisiae RM11-1a]
ERV1_YEAST - Mitochondrial FAD-linked sulfhydryl oxidase ERV1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S...
220.0 [0..90] [255..12]
gi|7576256 - gi|7576256|emb|CAB87993.1| augmenter of liver regeneration [Homo sapiens]
219.0 [0..84] [261..51]
gi|109127227 - gi|109127227|ref|XP_001082639.1| PREDICTED: similar to erv1-like growth factor isoform 2 [Macaca mul...
212.0 [0..82] [261..52]

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Predicted Domain #1
Region A:
Residues: [1-91]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFTIAERSF KILELPTTPT LLLRRQSHNY GYDYISPTHI ELSREATRLV IRRLQRTVLR  60
   61 LIRDPDFIMS AEANPEMDKE HHESPFAANR K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.616 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.584 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.517 a.2.7 tRNA-binding arm
View Download 0.505 a.24.17 Group V grass pollen allergen
View Download 0.475 f.15.1 Small-conductance potassium channel

Predicted Domain #2
Region A:
Residues: [92-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGASGAGKQD SNCRTCNDFK SWSKQQRLIS NVQSAKVKHM AAAEKLTV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [140-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAAEDPLPRD DCPLDKVRLG ISTWGLLHTM AAFYSDNPTD TEKRDMKTFF EVLSRLYPCE  60
   61 FCAKDFRTDL DVNPINVNSQ KELALWLCKF HNRVNDKLGK PLFDCTKVNE RWRDGWLDGS 120
  121 CD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.39794
Match: 1oqcA
Description: Augmenter of liver regeneration
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor 8.87150227689427 bayes_pls_golite062009
thiol oxidase activity 8.35075284009652 bayes_pls_golite062009
flavin-linked sulfhydryl oxidase activity 3.45360739809667 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 2.80346464149611 bayes_pls_golite062009
binding 1.31466847278576 bayes_pls_golite062009
protein binding 0.425029114798138 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle