YRC Public Data Repository - Protein Structure Prediction

Protein:	KDSA_ERWCT
Organism:	Pectobacterium atrosepticum
Length:	284 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KDSA_ERWCT.

Description	E-value	Query Range	Subject Range
KDSA_HISS2 - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Histophilus somni (strain 2336) GN=kdsA PE=3 SV=1	328.0	[0..1]	[284..1]
gi\|126209494, gi... - gi\|126209494\|ref\|YP_001054719.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Actinobacillus pleuropne... gi\|32033822 - gi\|32033822\|ref\|ZP_00134107.1\| COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase ... KDSA_ACTP7 - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Actinobacillus pleuropneumoniae serotype 7 (strain AP76...	327.0	[0..1]	[284..1]
KDSA_MANSM - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Mannheimia succiniciproducens (strain MBEL55E) GN=kdsA ...	327.0	[0..1]	[283..1]
KDSA_HAES1 - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Haemophilus somnus (strain 129Pt) GN=kdsA PE=3 SV=1	326.0	[0..1]	[284..1]
KDSA_SALPA - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella paratyphi A GN=kdsA PE=3 SV=1 KDSA_SALPK - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella paratyphi A (strain AKU_12601) GN=kdsA PE=3 ... KDSA_SALPA - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=k...	325.0	[0..1]	[284..1]
KDSA_HAEI8 - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Haemophilus influenzae (strain 86-028NP) GN=kdsA PE=3 S... gi\|144982589 - gi\|144982589\|gb\|EDJ90139.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Haemophilus influenzae R3021] gi\|145631799 - gi\|145631799\|ref\|ZP_01787559.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Haemophilus influenzae 22...	325.0	[0..1]	[283..1]
KDSA_HAEIN - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Haemophilus influenzae GN=kdsA PE=1 SV=1 KDSA_HAEIN - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 /...	325.0	[0..1]	[283..1]
KDSA_ACTSZ - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Actinobacillus succinogenes (strain ATCC 55618 / 130Z) ...	324.0	[0..1]	[283..1]
gi\|42631609 - gi\|42631609\|ref\|ZP_00157147.1\| COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase ... gi\|145639099, gi... - gi\|145639099\|ref\|ZP_01794707.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Haemophilus influenzae Pi... gi\|144978068, gi... - gi\|145629731\|ref\|ZP_01785527.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Haemophilus influenzae 22...	324.0	[0..1]	[283..1]
KDSA_SALCH - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella choleraesuis GN=kdsA PE=3 SV=1 gi\|238913672 - gi\|238913672\|ref\|ZP_04657509.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Salmonella enterica subsp... lcl\|NC_016856.1_... - [gene=kdsA] [protein=2-dehydro-3-deoxyphosphooctonate aldolase] [protein_id=YP_005237701.1] [locatio... KDSA_SALTY - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella typhimurium GN=kdsA PE=3 SV=1 gi\|168820510, gi... - gi\|205342596\|gb\|EDZ29360.1\| 3-deoxy-8-phosphooctulonate synthase [Salmonella enterica subsp. enteric... KDSA_SALCH - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella choleraesuis (strain SC-B67) GN=kdsA PE=3 SV... gi\|168462752, gi... - gi\|195634236\|gb\|EDX52588.1\| 3-deoxy-8-phosphooctulonate synthase [Salmonella enterica subsp. enteric... gi\|29137203, gi\|... - gi\|29141576\|ref\|NP_804918.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Salmonella enterica subsp. e... gi\|168260003, gi... - gi\|205350758\|gb\|EDZ37389.1\| 3-deoxy-8-phosphooctulonate synthase [Salmonella enterica subsp. enteric... gi\|16760665 - gi\|16760665\|ref\|NP_456282.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Salmonella enterica subsp. e... gi\|168241354, gi... - gi\|205339596\|gb\|EDZ26360.1\| 3-deoxy-8-phosphooctulonate synthase [Salmonella enterica subsp. enteric... KDSA_SALSV - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella schwarzengrund (strain CVM19633) GN=kdsA PE=... gi\|194459076, gi... - gi\|194472712\|ref\|ZP_03078696.1\| 3-deoxy-8-phosphooctulonate synthase [Salmonella enterica subsp. ent... KDSA_SALHS - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella heidelberg (strain SL476) GN=kdsA PE=3 SV=1 KDSA_SALNS - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella newport (strain SL254) GN=kdsA PE=3 SV=1 KDSA_SALPB - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN... gi\|168237826, gi... - gi\|197289259\|gb\|EDY28626.1\| 3-deoxy-8-phosphooctulonate synthase [Salmonella enterica subsp. enteric... KDSA_SALPB - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN... gi\|205332139, gi... - gi\|205332139\|gb\|EDZ18903.1\| 3-deoxy-8-phosphooctulonate synthase [Salmonella enterica subsp. enteric... gi\|167993215, gi... - gi\|205328652\|gb\|EDZ15416.1\| 3-deoxy-8-phosphooctulonate synthase [Salmonella enterica subsp. enteric... gi\|167553923, gi... - gi\|205321746\|gb\|EDZ09585.1\| 3-deoxy-8-phosphooctulonate synthase [Salmonella enterica subsp. enteric... gi\|213650658 - gi\|213650658\|ref\|ZP_03380711.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Salmonella enterica subsp... gi\|213586793 - gi\|213586793\|ref\|ZP_03368619.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Salmonella enterica subsp... gi\|213426499 - gi\|213426499\|ref\|ZP_03359249.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Salmonella enterica subsp... gi\|213051782 - gi\|213051782\|ref\|ZP_03344660.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Salmonella enterica subsp... KDSA_SALPC - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella paratyphi C (strain RKS4594) GN=kdsA PE=3 SV... gi\|214000497 - gi\|214000497\|ref\|ZP_03411232.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Salmonella enterica subsp... gi\|213850176 - gi\|213850176\|ref\|ZP_03381074.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Salmonella enterica subsp... KDSA_SALTY - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella typhimurium GN=kdsA PE=3 SV=1 gi\|200390905, gi... - gi\|200390905\|ref\|ZP_03217516.1\| 3-deoxy-8-phosphooctulonate synthase [Salmonella enterica subsp. ent... KDSA_SALDC - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella dublin (strain CT_02021853) GN=kdsA PE=3 SV=... KDSA_SALCH - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella choleraesuis GN=kdsA PE=3 SV=1 gi\|197262892, gi... - gi\|197262892\|ref\|ZP_03162966.1\| 3-deoxy-8-phosphooctulonate synthase [Salmonella enterica subsp. ent... KDSA_SALA4 - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella agona (strain SL483) GN=kdsA PE=3 SV=1 KDSA_SALTI - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella typhi GN=kdsA PE=3 SV=1 gi\|213028508 - gi\|213028508\|ref\|ZP_03342955.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Salmonella enterica subsp... KDSA_SALTY - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 70... KDSA_SALEP - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella enteritidis PT4 (strain P125109) GN=kdsA PE=... KDSA_SALG2 - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=k... KDSA_SALTI - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Salmonella typhi GN=kdsA PE=3 SV=1 gi\|204927714, gi... - gi\|204927714\|ref\|ZP_03218915.1\| 3-deoxy-8-phosphooctulonate synthase [Salmonella enterica subsp. ent...	324.0	[0..1]	[284..1]

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Predicted Domain #1

Region A:
Residues: [1-284]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNKVVKIGD IPVANDLPFV LFGGMNVLES RDLAMRICEH YVTVTQKLGI PYVFKASFDK  60
   61 ANRSSIHSYR GPGLEEGMKI FQELKQTFGV KIITDVHDSH QAQPVADVVD VIQLPAFLAR 120
  121 QTDLVEAMAK TGAVINVKKP QFVSPGQMGN IVDKFIEGGN DQIILCDRGS NFGYDNLVVD 180
  181 MLGFNVMKHA SNGSPVIFDV THALQCRDPF GAASGGRRGQ VTELARAGMA VGLAGLFIEA 240
  241 HPDPANAKCD GPSALPLDKL EPFLQQIKAI DDLVKSFPEL DTSN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	89.0
Match:	1o60A
Description:	Crystal structure of KDO-8-phosphate synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-deoxy-8-phosphooctulonate synthase activity	4.43037733440316	bayes_pls_golite062009
3-deoxy-7-phosphoheptulonate synthase activity	2.72022882819661	bayes_pls_golite062009
catalytic activity	2.67031204377352	bayes_pls_golite062009
fructose-bisphosphate aldolase activity	0.840107349031025	bayes_pls_golite062009
lyase activity	0.740424046054758	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	0.643395146148785	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	0.490222900376021	bayes_pls_golite062009
transferase activity	0.464721888799972	bayes_pls_golite062009
aldehyde-lyase activity	0.351872954170322	bayes_pls_golite062009
transaldolase activity	0.337067552042715	bayes_pls_golite062009
oxo-acid-lyase activity	0.0484922693826344	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: