YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|56554195
Organism:	Pyrococcus horikoshii
Length:	192 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|56554195.

Description	E-value	Query Range	Subject Range
gi\|3258376, gi\|1... - gi\|3258376\|dbj\|BAA31059.1\| 192aa long hypothetical protein [Pyrococcus horikoshii OT3], gi\|14591674\|... gi\|7519353, gi\|8... - gi\|85544430\|pdb\|2CWE\|A Chain A, Crystal Structure Of Hypothetical Transcriptional Regulator Protein,...	137.0	[0..2]	[192..2]
gi\|3080560 - gi\|3080560\|dbj\|BAA25806.1\| transcription regulatory protein [Pyrococcus furiosus] gi\|3080560, gi\|1... - gi\|3080560\|dbj\|BAA25806.1\| transcription regulatory protein [Pyrococcus furiosus], gi\|18976602\|ref\|N...	130.0	[0..3]	[192..3]
gi\|14521905, gi\|... - gi\|5459125\|emb\|CAB50611.1\| transcriptional regulatory protein, arsR family [Pyrococcus abyssi GE5], ... gi\|7521491, gi\|5... - pir\|\|E75021 probable transcription regulatory protein PAB1227 - Pyrococcus abyssi (strain Orsay), gi...	128.0	[0..2]	[192..2]
gi\|95112931 - gi\|95112931\|emb\|CAK17659.1\| putative transcriptional regulator, ArsR family [Pseudomonas entomophila... gi\|104783944, gi... - gi\|95112931\|emb\|CAK17659.1\| putative transcriptional regulator, ArsR family [Pseudomonas entomophila...	126.0	[0..8]	[191..13]
gi\|57641816, gi\|... - gi\|57641816\|ref\|YP_184294.1\| ArsR family transcriptional regulator [Thermococcus kodakarensis KOD1],...	126.0	[0..4]	[192..3]
gi\|94501836, gi\|... - gi\|94501836\|ref\|ZP_01308348.1\| transcriptional regulator, ArsR family protein [Oceanobacter sp. RED6...	125.0	[0..3]	[191..12]
gi\|68347371, gi\|... - gi\|70733072\|ref\|YP_262845.1\| ArsR family transcriptional regulator [Pseudomonas fluorescens Pf-5], g...	125.0	[0..5]	[191..20]
gi\|77385492, gi\|... - gi\|77461489\|ref\|YP_350996.1\| ArsR family transcriptional regulator [Pseudomonas fluorescens Pf0-1], ...	124.0	[0..5]	[191..11]
tr\|E4R8H2\|E4R8H2... - ArsR family transcriptional regulator OS=Pseudomonas putida (strain BIRD-1) GN=PPUBIRD1_4750 PE=4 SV... gi\|26991644, gi\|... - gi\|26991644\|ref\|NP_747069.1\| ArsR family transcriptional regulator [Pseudomonas putida KT2440], gi\|2... gi\|82713093, gi\|... - gi\|82739843\|ref\|ZP_00902627.1\| regulatory protein, ArsR [Pseudomonas putida F1], gi\|82713093\|gb\|EAP4... tr\|I7C1U1\|I7C1U1... - ArsR family transcriptional regulator OS=Pseudomonas putida (strain DOT-T1E) GN=T1E_1144 PE=4 SV=1	120.0	[0..5]	[191..10]
gi\|88776154, gi\|... - gi\|88801125\|ref\|ZP_01116671.1\| SAM-dependent methyltransferase [Reinekea sp. MED297], gi\|88776154\|gb...	119.0	[0..5]	[191..1]

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Predicted Domain #1

Region A:
Residues: [1-192]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 XAKKVKVITD PEVIKVXLED TRRKILKLLR NKEXTISQLS EILGKTPQTI YHHIEKLKEA  60
   61 GLVEVKRTEX KGNLVEKYYG RTADVFYINL YLGDEELRYI ARSRLKTKID IFKRLGYQFE 120
  121 ENELLNIXDR XSQKEFDATV RISKYIEEKE DALKDFSNED IIHAIEWLST AELARDEEYL 180
  181 ELLKRLGSIL KR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.69897
Match:	1ulyA
Description:	Crystal structure analysis of the ArsR homologue DNA-binding protein from P. horikoshii OT3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.835523092977445	bayes_pls_golite062009
transcription regulator activity	0.4843036104266	bayes_pls_golite062009
nucleic acid binding	0.37117756729668	bayes_pls_golite062009
DNA binding	0.3118855114645	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: