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View Structure Prediction Details

Protein: gi|78070714, gi|...
Organism: Homo sapiens
Length: 214 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|78070714, gi|....

Description E-value Query
Range
Subject
Range
gi|114595731 - gi|114595731|ref|XP_001144487.1| PREDICTED: La ribonucleoprotein domain family, member 7 isoform 11 ...
2.0E-72 [1..214] [382..595]
gi|7705401, gi|7... - gi|7705401|ref|NP_057732.1| hypothetical protein LOC51574 [Homo sapiens], gi|7643776|gb|AAF65503.1|A...
1.0E-71 [1..214] [1..214]
gi|109075411 - gi|109075411|ref|XP_001092044.1| PREDICTED: similar to multi sex combs CG12058-PA [Macaca mulatta]
8.0E-70 [1..214] [336..548]
LARP7_MACFA - La-related protein 7 OS=Macaca fascicularis GN=LARP7 PE=2 SV=1
4.0E-69 [1..214] [369..581]
LARP7_MOUSE - La-related protein 7 OS=Mus musculus GN=Larp7 PE=1 SV=2
gi|151555613, gi... - gi|157170500|gb|AAI53030.1| La ribonucleoprotein domain family, member 7 [synthetic construct], gi|1...
2.0E-66 [1..214] [365..570]

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Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEEVIPLRV LSKSEWMDLK KEYLALQKAS MASLKKTISQ IKSESEMETD SGVPQNTGMK  60
   61 NEKTANREEC RTQEKVNAT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.522879
Match: 1zh5A
Description: Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [80-214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPQFVSGVIV KIISTEPLPG RKQVRDTLAA ISEVLYVDLL EGDTECHARF KTPEDAQAVI  60
   61 NAYTEINKKH CWKLEILSGD HEQRYWQKIL VDRQAKLNQP REKKRGTEKL ITKAEKIRLA 120
  121 KTQQASKHIR FSEYD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.522879
Match: 1owxA
Description: Lupus LA protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle