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View Structure Prediction Details

Protein: gi|61361812, gi|...
Organism: synthetic construct
Length: 600 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|61361812, gi|....

Description E-value Query
Range
Subject
Range
gi|114560153 - gi|114560153|ref|XP_513875.2| PREDICTED: lamin A/C [Pan troglodytes]
1.0E-68 [10..564] [451..985]
gi|60653745, gi|... - gi|60653745|gb|AAX29566.1| lamin B2 [synthetic construct], gi|32880115|gb|AAP88888.1| lamin B2 [synt...
3.0E-52 [1..600] [1..600]
gi|49115181, gi|... - gi|49115181|gb|AAH73219.1| Lmnb2-A-prov protein [Xenopus laevis], gi|147901703|ref|NP_001080947.1| l...
3.0E-51 [2..600] [12..624]
gi|76622425, gi|... - gi|76622425|ref|XP_594479.2| PREDICTED: similar to Lamin B2 [Bos taurus], gi|194668843|ref|XP_594479...
3.0E-50 [16..600] [40..628]
gi|109480210, gi... - gi|109481544|ref|XP_001076027.1| PREDICTED: similar to Lamin-B2 [Rattus norvegicus], gi|109480210|re...
6.0E-49 [16..600] [32..616]
gi|4678403, gi|1... - gi|4678403|emb|CAB41015.1| lamin B2 [Danio rerio], gi|18858981|ref|NP_571077.1| lamin b2 [Danio reri...
7.0E-49 [1..600] [1..583]
LMNB2_CHICK - Lamin-B2 OS=Gallus gallus GN=LMNB2 PE=2 SV=1
8.0E-49 [16..600] [15..600]
gi|228591 - gi|228591|prf||1807162A lamin B2
1.0E-46 [16..600] [14..596]

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Predicted Domain #1
Region A:
Residues: [1-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATPLPGRAG GPATPLSPTR LSRLQEKEEL RELNDRLAHY IDRVRALELE NDRLLLKISE  60
   61 KEEVTTREVS GIKALYESEL ADARRVLDET ARERARLQIE IGKLRAELDE VNKSAKKREG 120
  121 ELTVAQGRVK DLESLFHRSE VELAAALSDK RGLESDVAEL RAQLAKAEDG HAVAKKQLEK 180
  181 ETLMRVDLEN RCQSLQEELD FRKSVFEEEV RETRRRHERR LVEVDSSRQQ EYDFKMAQAL 240
  241 EELRSQHDEQ VRLYKLELEQ TYQAKLDSAK LSSDQNDKAA SAAREELKEA RMRLESLSYQ 300
  301 LSGLQKQASA AEDRIRELEE AMAGERDKFR KMLDAKEQEM TEMRDVMQQQ LAEYQELLDV 360
  361 KLALDMEINA YRKLLEGEEE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.045757
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [381-428]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLKLSPSPSS RVTVSRATSS SSGSLSATGR LGRSKRKRLE VEEPLGSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [429-600]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSVLGTGTGG SGGFHLAQQA SASGSVSIEE IDLEGKFVQL KNNSDKDQSL GNWRIKRQVL  60
   61 EGEEIAYKFT PKYILRAGQM VTVWAAGAGV AHSPPSTLVW KGQSSWGTGE SFRTVLVNAD 120
  121 GEEVAMRTVK KSSVMRENEN GEEEEEEAEF GEEDLFHQQG DPRTTSRGCY VM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 1ivtA
Description: Lamin A/C globular tail domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.29024114419453 bayes_pls_golite062009
protein binding 1.13460840277514 bayes_pls_golite062009
structural molecule activity 0.619687426425363 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle