YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|157065305, gi...
Organism:	Escherichia coli HS
Length:	266 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|157065305, gi....

Description	E-value	Query Range	Subject Range
gi\|166857129, gi... - gi\|76795368\|ref\|ZP_00777741.1\| Periplasmic binding protein [Thermoanaerobacter ethanolicus ATCC 3322... gi\|241903823, gi... - gi\|241903823\|ref\|ZP_04788540.1\| periplasmic binding protein [Thermoanaerobacter brockii subsp. finni...	253.0	[0..3]	[263..43]
gi\|114843982, gi... - gi\|167040563\|ref\|YP_001663548.1\| periplasmic binding protein [Thermoanaerobacter sp. X514], gi\|16685...	251.0	[0..3]	[263..43]
gi\|20806884 - gi\|20806884\|ref\|NP_622055.1\| ABC-type Fe3+-siderophores transport systems, periplasmic components [T... gi\|20806884, gi\|... - gi\|20806884\|ref\|NP_622055.1\| ABC-type Fe3+-siderophores transport systems, periplasmic components [T...	248.0	[0..3]	[263..55]
gi\|85721163, gi\|... - gi\|85858072\|ref\|YP_460274.1\| ABC-type transporter cobalamide binding protein [Syntrophus aciditrophi...	235.0	[0..3]	[263..27]
gi\|5457942, gi\|1... - gi\|5457942\|emb\|CAB49432.1\| Iron (III) ABC transporter, periplasmic-binding protein, putative [Pyroco... gi\|7521157, gi\|5... - pir\|\|A75169 probable iron (III) ABC transporter, periplasmic-binding protein PAB0349 - Pyrococcus ab...	228.0	[0..2]	[263..63]
gi\|51893067, gi\|... - gi\|51893067\|ref\|YP_075758.1\| iron ABC transporter substrate-binding protein [Symbiobacterium thermop...	228.0	[0..4]	[263..65]
gi\|3258088, gi\|1... - gi\|3258088\|dbj\|BAA30771.1\| 345aa long hypothetical protein [Pyrococcus horikoshii OT3], gi\|14591428\|... gi\|7519230 - pir\|\|C71046 hypothetical protein PH1659 - Pyrococcus horikoshii	227.0	[0..1]	[263..58]
gi\|57640800, gi\|... - gi\|57640800\|ref\|YP_183278.1\| vitamin B12 transport protein precursor [Thermococcus kodakarensis KOD1...	225.0	[0..2]	[263..67]
gi\|220932734, gi... - gi\|89211052\|ref\|ZP_01189431.1\| Periplasmic binding protein [Halothermothrix orenii H 168], gi\|891593...	225.0	[0..3]	[262..33]

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Predicted Domain #1

Region A:
Residues: [1-266]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKSLFRALV ALSFLAPLWL NAAPRVITLS PANTELAFAA GITPVGVSSY SDYPPQAQKI  60
   61 EQVSTWQGMN LERIVALKPD LVIAWRGGNA ERQVDQLASL GIKVMWVDAT SIEQIANALR 120
  121 QLAPWSPQPD KAEQAAQSLL DQYAQLKAQY ADKPKKRVFL QFGINPPFTS GKESIQNQVL 180
  181 EVCGGENIFK DSRVPWPQVS REQVLARSPQ AIVITGGPDQ IPKIKQYWGE QLKIPVIPLT 240
  241 SDWFERASPR IILAAQQLCN ALSQVD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.30103
Match:	1n2zA
Description:	Vitamin B12 binding protein BtuF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	3.67298279110452	bayes_pls_golite062009
transmembrane transporter activity	3.28968508115123	bayes_pls_golite062009
substrate-specific transporter activity	2.58693520442871	bayes_pls_golite062009
primary active transmembrane transporter activity	2.54812677397783	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	2.5446605673848	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	2.52703679403613	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	2.52398066978703	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	2.52350775380228	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.52293027691627	bayes_pls_golite062009
ion transmembrane transporter activity	2.48221032634964	bayes_pls_golite062009
active transmembrane transporter activity	2.44277891725345	bayes_pls_golite062009
cation transmembrane transporter activity	2.43432715933868	bayes_pls_golite062009
vitamin transporter activity	1.90171564206008	bayes_pls_golite062009
ATPase activity, coupled	1.89049387988996	bayes_pls_golite062009
hydrolase activity	1.86998437001641	bayes_pls_golite062009
metal ion transmembrane transporter activity	1.82149959434919	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	1.67055279691251	bayes_pls_golite062009
ATPase activity	1.65488400668431	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.59760820263042	bayes_pls_golite062009
pyrophosphatase activity	1.52739129331837	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.50948117450196	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.50661057394414	bayes_pls_golite062009
binding	1.19129262734542	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	1.09319368287943	bayes_pls_golite062009
cobalamin binding	0.89809989169321	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	0.717553706660499	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: