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View Structure Prediction Details

Protein: gi|61358976, gi|...
Organism: synthetic construct
Length: 135 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|61358976, gi|....

Description E-value Query
Range		 Subject
Range
gi|191126 - gi|191126|gb|AAA36995.1| 14 kDa beta-galactoside-binding lectin
LEG1_CRIGR - Galectin-1 OS=Cricetulus griseus GN=LGALS1 PE=1 SV=2
 4.0E-45 [1..135] [1..135]
gi|23342428|emb|... - unnamed protein product [Rattus sp.]
LEG1_RAT - Galectin-1 OS=Rattus norvegicus GN=Lgals1 PE=1 SV=2
 9.0E-45 [1..135] [1..135]
gi|109149582 - gi|109149582|ref|XP_001083427.1| PREDICTED: lectin, galactoside-binding, soluble, 1 (galectin 1) iso...
 9.0E-45 [1..135] [1..135]
LEG1_MOUSE - Galectin-1 OS=Mus musculus GN=Lgals1 PE=1 SV=3
 1.0E-44 [1..135] [1..135]
gi|30584667, gi|... - gi|61369162|gb|AAX43294.1| lectin galactoside-binding soluble 1 [synthetic construct], gi|61369156|g...
 3.0E-44 [1..135] [1..135]
LEG1_PONPY - Galectin-1 - Pongo pygmaeus (Orangutan)
LEG1_PONAB - Galectin-1 OS=Pongo abelii GN=LGALS1 PE=2 SV=3
 8.0E-44 [1..135] [1..135]
LEG1_SHEEP - Galectin-1 OS=Ovis aries GN=LGALS1 PE=1 SV=2
 1.0E-43 [1..135] [1..135]
LEG1_PIG - Galectin-1 OS=Sus scrofa GN=LGALS1 PE=2 SV=3
 2.0E-43 [1..135] [1..135]

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Predicted Domain #1
Region A:
Residues: [1-135] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MACGLVASNL NLKPGECLRV RGEVAPDAKS FVLNLGKDSN NLCLHFNPRF NAHGDANTIV  60
   61 CNSKDGGAWG TEQREAVFPF QPGSVAEVCI TFDQANLTVK LPDGYEFKFP NRLNLEAINY 120
  121 MAADGDFKIK CVAFD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.522879
Match: 1gzwA
Description: X-RAY CRYSTAL STRUCTURE OF HUMAN GALECTIN-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycosaminoglycan binding 2.70103238455595 bayes_pls_golite062009
binding 2.40096962515027 bayes_pls_golite062009
polysaccharide binding 2.35851723238763 bayes_pls_golite062009
monosaccharide binding 2.09529521879228 bayes_pls_golite062009
carbohydrate binding 1.90829797790335 bayes_pls_golite062009
protein binding 1.80794638640093 bayes_pls_golite062009
heparin binding 1.60966215355794 bayes_pls_golite062009
extracellular matrix binding 1.41229380365824 bayes_pls_golite062009
sugar binding 1.27754120053722 bayes_pls_golite062009
fibronectin binding 1.10309233016451 bayes_pls_golite062009
galactoside binding 1.08479183125487 bayes_pls_golite062009
receptor binding 0.9012250808046 bayes_pls_golite062009
pattern binding 0.83687933614214 bayes_pls_golite062009
extracellular matrix structural constituent 0.5068011550246 bayes_pls_golite062009
transcription regulator activity 0.372701974560119 bayes_pls_golite062009
nucleic acid binding 0.216086300988177 bayes_pls_golite062009
DNA binding 0.157628282318248 bayes_pls_golite062009
growth factor activity 0.119475011376319 bayes_pls_golite062009
fibroblast growth factor 2 binding 0.0714976455077903 bayes_pls_golite062009
fibrinogen binding 0.0714976455077903 bayes_pls_golite062009
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