YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|121729381, gi...
Organism:	Vibrio cholerae V52
Length:	270 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|121729381, gi....

Description	E-value	Query Range	Subject Range
ATP6_VIBAL - ATP synthase subunit a OS=Vibrio alginolyticus GN=atpB PE=3 SV=1 gi\|91226232, gi\|... - gi\|91226232\|ref\|ZP_01261072.1\| F0F1 ATP synthase subunit A [Vibrio alginolyticus 12G01], gi\|91189243... gi\|254229971, gi... - gi\|75855550\|ref\|ZP_00763198.1\| COG0356: F0F1-type ATP synthase, subunit a [Vibrio sp. Ex25], gi\|2542...	213.0	[0..1]	[270..1]
gi\|149748126, gi... - gi\|153838503\|ref\|ZP_01991170.1\| ATP synthase a chain [Vibrio parahaemolyticus AQ3810], gi\|149748126\|... ATP6_VIBPA - ATP synthase subunit a OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=atpB PE=3 ... ATP6_VIBPA - ATP synthase subunit a OS=Vibrio parahaemolyticus GN=atpB PE=3 SV=1	213.0	[0..1]	[270..1]
ATP6_VIBVU - ATP synthase subunit a OS=Vibrio vulnificus (strain CMCP6) GN=atpB PE=3 SV=1 ATP6_VIBVY - ATP synthase subunit a OS=Vibrio vulnificus (strain YJ016) GN=atpB PE=3 SV=1 ATP6_VIBVU - ATP synthase subunit a OS=Vibrio vulnificus GN=atpB PE=3 SV=1	211.0	[0..1]	[270..1]
ATP6_VIBFM - ATP synthase subunit a OS=Vibrio fischeri (strain MJ11) GN=atpB PE=3 SV=1 ATP6_VIBF1 - ATP synthase subunit a OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=atpB PE=3 SV=1	208.0	[0..1]	[270..1]
gi\|90325217, gi\|... - gi\|90413748\|ref\|ZP_01221736.1\| ATP synthase subunit A [Photobacterium profundum 3TCK], gi\|90325217\|g...	201.0	[0..1]	[269..1]
gi\|84375926, gi\|... - gi\|84393410\|ref\|ZP_00992167.1\| ATP synthase subunit A [Vibrio splendidus 12B01], gi\|84375926\|gb\|EAP9...	198.0	[0..5]	[270..1]
gi\|629605, gi\|515963 - pir\|\|S42658 H+-transporting two-sector ATPase (EC 3.6.3.14) protein 6 precursor - radish mitochondri...	198.0	[0..16]	[268..176]
gi\|86147160, gi\|... - gi\|86147160\|ref\|ZP_01065476.1\| ATP synthase subunit A [Vibrio sp. MED222], gi\|85835044\|gb\|EAQ53186.1... gi\|218324048, gi... - gi\|218711029\|ref\|YP_002418650.1\| F0F1 ATP synthase subunit A [Vibrio splendidus LGP32], gi\|218324048...	197.0	[0..5]	[270..1]
gi\|90581145, gi\|... - gi\|90581145\|ref\|ZP_01236944.1\| ATP synthase subunit A [Vibrio angustum S14], gi\|90437666\|gb\|EAS62858...	197.0	[0..1]	[269..1]
gi\|89074722, gi\|... - gi\|89074722\|ref\|ZP_01161180.1\| ATP synthase subunit A [Photobacterium sp. SKA34], gi\|89049486\|gb\|EAR...	197.0	[0..1]	[269..1]

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Predicted Domain #1

Region A:
Residues: [1-65]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAPGEALTP SSYITHHLTN LSTYKLGLVA EESSFWNVHI DSLFFSVLTG LIFLGVFRAV  60
   61 ARKAT

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [66-270]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGVPGKLQCA VEMVVEFVDK NVKDTFHGRN PLIAPLALTI FCWVFLMNLM DLVPIDFLPY  60
   61 PAQHWLGIPY LKVVPSADVN ITMAMALGVF ALMIYYSIKV KGLGGFAKEL ALHPFNHWIM 120
  121 IPFNLLIEVV SLLAKPLSLG MRLFGNMFAG EVVFILCAAM LPWYLQWMGS LPWAIFHILV 180
  181 ILIQSFVFMM LTIVYMSMAH EDNDH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.69897
Match:	1c17M
Description:	F1F0 ATP synthase subunit A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrogen ion transporting ATP synthase activity, rotational mechanism	14.916062574431	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	13.3765277511271	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	11.6266555949852	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	10.5141571800158	bayes_pls_golite062009
cation transmembrane transporter activity	6.7755175807552	bayes_pls_golite062009
ion transmembrane transporter activity	6.66886754588748	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	6.24164033661356	bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism	5.34968915140418	bayes_pls_golite062009
transporter activity	4.44683838532142	bayes_pls_golite062009
substrate-specific transporter activity	4.37473908570954	bayes_pls_golite062009
transmembrane transporter activity	4.36056336888635	bayes_pls_golite062009
cation-transporting ATPase activity	3.33662712450334	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	1.11865103919948	bayes_pls_golite062009
primary active transmembrane transporter activity	0.517601509369888	bayes_pls_golite062009
active transmembrane transporter activity	0.511311810386796	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.510137962484563	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.476924701765357	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.473395661531507	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.473285892250811	bayes_pls_golite062009
catalytic activity	0.276917867171685	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.242742762516199	bayes_pls_golite062009
pyrophosphatase activity	0.201337507209354	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.191294406773539	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.188721983770471	bayes_pls_golite062009
ATPase activity, coupled	0.110491424400621	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: