YRC Public Data Repository - Protein Structure Prediction

Protein:	HTPX_YERP3
Organism:	Yersinia pseudotuberculosis IP 31758
Length:	293 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HTPX_YERP3.

Description	E-value	Query Range	Subject Range
HTPX_ERWCT - Protease HtpX OS=Erwinia carotovora subsp. atroseptica GN=htpX PE=3 SV=1 HTPX_PECAS - Protease HtpX OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) GN=htpX PE=3 SV=1	1.0E-67	[1..293]	[1..293]
gi\|238724840, gi... - gi\|77975215\|ref\|ZP_00830751.1\| COG0501: Zn-dependent protease with chaperone function [Yersinia fred...	3.0E-67	[1..293]	[1..293]
gi\|238728851, gi... - gi\|77980102\|ref\|ZP_00835517.1\| COG0501: Zn-dependent protease with chaperone function [Yersinia inte...	8.0E-67	[1..293]	[1..293]
gi\|16760732 - gi\|16760732\|ref\|NP_456349.1\| heat shock protein HtpX [Salmonella enterica subsp. enterica serovar Ty... HTPX_SALDC - Protease HtpX OS=Salmonella dublin (strain CT_02021853) GN=htpX PE=3 SV=1 HTPX_SALPK - Protease HtpX OS=Salmonella paratyphi A (strain AKU_12601) GN=htpX PE=3 SV=1 HTPX_SALTY - Protease HtpX OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=htpX PE=3 SV=1 gi\|197241190, gi... - gi\|197262935\|ref\|ZP_03163009.1\| M48B family peptidase [Salmonella enterica subsp. enterica serovar S... gi\|29137137, gi\|... - gi\|29141510\|ref\|NP_804852.1\| heat shock protein HtpX [Salmonella enterica subsp. enterica serovar Ty... HTPX_SALA4 - Protease HtpX OS=Salmonella agona (strain SL483) GN=htpX PE=3 SV=1 HTPX_SALEP - Protease HtpX OS=Salmonella enteritidis PT4 (strain P125109) GN=htpX PE=3 SV=1 HTPX_SALG2 - Protease HtpX OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=htpX PE=3 SV=1 gi\|204931090, gi... - gi\|204931090\|ref\|ZP_03221916.1\| M48B family peptidase [Salmonella enterica subsp. enterica serovar J... gi\|199603491, gi... - gi\|200391046\|ref\|ZP_03217657.1\| M48B family peptidase [Salmonella enterica subsp. enterica serovar V... gi\|205342580, gi... - gi\|205342580\|gb\|EDZ29344.1\| M48B family peptidase [Salmonella enterica subsp. enterica serovar Welte... gi\|195634383, gi... - gi\|195634383\|gb\|EDX52735.1\| M48B family peptidase [Salmonella enterica subsp. enterica serovar Newpo... gi\|205350590, gi... - gi\|205350590\|gb\|EDZ37221.1\| M48B family peptidase [Salmonella enterica subsp. enterica serovar Hadar... gi\|168241443, gi... - gi\|205339124\|gb\|EDZ25888.1\| M48B family peptidase [Salmonella enterica subsp. enterica serovar Heide... HTPX_SALSV - Protease HtpX OS=Salmonella schwarzengrund (strain CVM19633) GN=htpX PE=3 SV=1 gi\|194470673, gi... - gi\|194470673\|ref\|ZP_03076657.1\| M48B family peptidase [Salmonella enterica subsp. enterica serovar K... HTPX_SALHS - Protease HtpX OS=Salmonella heidelberg (strain SL476) GN=htpX PE=3 SV=1 HTPX_SALNS - Protease HtpX OS=Salmonella newport (strain SL254) GN=htpX PE=3 SV=1 HTPX_SALCH - Protease HtpX OS=Salmonella choleraesuis GN=htpX PE=3 SV=1 HTPX_SALPC - Protease HtpX OS=Salmonella paratyphi C (strain RKS4594) GN=htpX PE=3 SV=1 HTPX_SALPA - Protease HtpX OS=Salmonella paratyphi A GN=htpX PE=3 SV=1 HTPX_SALTI - Protease HtpX OS=Salmonella typhi GN=htpX PE=3 SV=1 HTPX_SALCH - Probable protease htpX OS=Salmonella choleraesuis GN=htpX PE=3 SV=1 HTPX_SALTY - Protease HtpX OS=Salmonella typhimurium GN=htpX PE=3 SV=1 HTPX_SALAR - Protease HtpX OS=Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) GN=htpX PE=3 SV=1 HTPX_SALTY - Probable protease htpX OS=Salmonella typhimurium GN=htpX PE=3 SV=1 lcl\|NC_016856.1_... - [gene=htpX] [protein=heat shock protein HtpX] [protein_id=YP_005237790.1] [location=complement(19514... gi\|197288677, gi... - gi\|197288677\|gb\|EDY28052.1\| M48B family peptidase [Salmonella enterica subsp. enterica serovar Schwa... HTPX_SALCH - Protease HtpX OS=Salmonella choleraesuis (strain SC-B67) GN=htpX PE=3 SV=1 gi\|168234256, gi... - gi\|205331764\|gb\|EDZ18528.1\| M48B family peptidase [Salmonella enterica subsp. enterica serovar Kentu... HTPX_SALPA - Protease HtpX OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=htpX PE=3 SV=1 gi\|167993796, gi... - gi\|205328234\|gb\|EDZ14998.1\| M48B family peptidase [Salmonella enterica subsp. enterica serovar 4,[5]... HTPX_SALTI - Probable protease htpX OS=Salmonella typhi GN=htpX PE=3 SV=1 gi\|167553469, gi... - gi\|205322082\|gb\|EDZ09921.1\| M48B family peptidase [Salmonella enterica subsp. enterica serovar Saint...	9.0E-67	[1..293]	[1..293]
gi\|194417239, gi... - gi\|83569085\|ref\|ZP_00920546.1\| COG0501: Zn-dependent protease with chaperone function [Shigella dyse...	1.0E-66	[1..293]	[1..293]
gi\|188013563, gi... - gi\|188013563\|gb\|EDU51685.1\| M48B family peptidase [Escherichia coli O157:H7 str. EC4113], gi\|1687526... gi\|168758592, gi... - gi\|189354623\|gb\|EDU73042.1\| M48B family peptidase [Escherichia coli O157:H7 str. EC4401], gi\|1687585... gi\|189360375, gi... - gi\|189360375\|gb\|EDU78794.1\| M48B family peptidase [Escherichia coli O157:H7 str. EC4486], gi\|1687708... gi\|188999448, gi... - gi\|188999448\|gb\|EDU68434.1\| M48B family peptidase [Escherichia coli O157:H7 str. EC4076], gi\|1687831... gi\|254793453, gi... - gi\|254793453\|ref\|YP_003078290.1\| predicted endopeptidase [Escherichia coli O157:H7 str. TW14359], gi... gi\|193066804, gi... - gi\|75254939\|ref\|ZP_00726891.1\| COG0501: Zn-dependent protease with chaperone function [Escherichia c... HTPX_ECOLC - Protease HtpX OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=htpX PE=3 SV=1 gi\|237705781, gi... - gi\|237705781\|ref\|ZP_04536262.1\| heat shock protein HtpX [Escherichia sp. 3_2_53FAA], gi\|226900538\|gb... HTPX_SHISS - Protease HtpX OS=Shigella sonnei (strain Ss046) GN=htpX PE=3 SV=1 gi\|227885744, gi... - gi\|227885744\|ref\|ZP_04003549.1\| M48 family endopeptidase HtpX [Escherichia coli 83972], gi\|227837317... gi\|75208008, gi\|... - gi\|75208008\|ref\|ZP_00708426.1\| COG0501: Zn-dependent protease with chaperone function [Escherichia c... gi\|75239751 - gi\|75239751\|ref\|ZP_00723714.1\| COG0501: Zn-dependent protease with chaperone function [Escherichia c... HTPX_SHIDS - Protease HtpX OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=htpX PE=3 SV=1 HTPX_SHIBS - Protease HtpX OS=Shigella boydii serotype 4 (strain Sb227) GN=htpX PE=3 SV=1 HTPX_ECO57 - Protease HtpX OS=Escherichia coli O157:H7 GN=htpX PE=2 SV=1 gi\|217317954, gi... - gi\|217328607\|ref\|ZP_03444688.1\| M48B family peptidase [Escherichia coli O157:H7 str. TW14588], gi\|21... HTPX_ECOL6 - Protease HtpX OS=Escherichia coli O6 GN=htpX PE=3 SV=1 HTPX_ECO8A - Protease HtpX OS=Escherichia coli O8 (strain IAI1) GN=htpX PE=3 SV=1 HTPX_ECO45 - Protease HtpX OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=htpX PE=3 SV=1 HTPX_ECO81 - Protease HtpX OS=Escherichia coli O81 (strain ED1a) GN=htpX PE=3 SV=1 HTPX_ECO24 - Protease HtpX OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=htpX PE=3 SV=1 HTPX_ECO55 - Protease HtpX OS=Escherichia coli (strain 55989 / EAEC) GN=htpX PE=3 SV=1 HTPX_ECOHS - Protease HtpX OS=Escherichia coli O9:H4 (strain HS) GN=htpX PE=3 SV=1 HTPX_ECO7I - Protease HtpX OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=htpX PE=3 SV=1 HTPX_ECOLU - Protease HtpX OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=htpX PE=3 SV=1 HTPX_SHIB3 - Protease HtpX OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=htpX PE=3 SV=1 HTPX_ECOK1 - Protease HtpX OS=Escherichia coli O1:K1 / APEC GN=htpX PE=3 SV=1 HTPX_ECOSM - Protease HtpX OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=htpX PE=3 SV=1 gi\|124498872, gi... - gi\|124530977\|ref\|ZP_01701433.1\| HtpX domain protein [Escherichia coli B], gi\|124498872\|gb\|EAY46373.1... gi\|170769359, gi... - gi\|170769359\|ref\|ZP_02903812.1\| M48B family peptidase [Escherichia albertii TW07627], gi\|170121683\|g... gi\|188488604, gi... - gi\|188493405\|ref\|ZP_03000675.1\| M48B family peptidase HtpX [Escherichia coli 53638], gi\|188488604\|gb... gi\|208810633, gi... - gi\|208810633\|ref\|ZP_03252509.1\| M48B family peptidase [Escherichia coli O157:H7 str. EC4206], gi\|208... gi\|208731013, gi... - gi\|208816670\|ref\|ZP_03257790.1\| M48B family peptidase [Escherichia coli O157:H7 str. EC4045], gi\|208... gi\|208741454, gi... - gi\|208821331\|ref\|ZP_03261651.1\| M48B family peptidase [Escherichia coli O157:H7 str. EC4042], gi\|208... HTPX_ECO5E - Protease HtpX OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=htpX PE=3 SV=1 HTPX_ECOSE - Protease HtpX OS=Escherichia coli (strain SE11) GN=htpX PE=3 SV=1 HTPX_ECOUT - Protease HtpX OS=Escherichia coli (strain UTI89 / UPEC) GN=htpX PE=3 SV=1 HTPX_SHIFL - Protease HtpX OS=Shigella flexneri GN=htpX PE=3 SV=1 gi\|15831793, gi\|... - gi\|15831793\|ref\|NP_310566.1\| heat shock protein HtpX [Escherichia coli O157:H7 str. Sakai], gi\|13362... HTPX_ECOL5 - Protease HtpX OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=htpX PE=3 SV=1 HTPX_SHIF8 - Protease HtpX OS=Shigella flexneri serotype 5b (strain 8401) GN=htpX PE=3 SV=1 gi\|24112780, gi\|... - ref\|NP_707290.1\| heat shock protein HtpX [Shigella flexneri 2a str. 301], gb\|AAN42997.1\| heat shock... HTPX_ECOL6 - Protease HtpX OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=htpX PE=3 SV=1 gi\|209767788, gi... - pir\|\|C90946 heat shock protein HtpX [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0...	1.0E-66	[1..293]	[1..293]
gi\|25296090 - gi\|25296090\|pir\|\|G85794 heat shock protein, integral membrane protein [imported] - Escherichia coli ... gi\|15802243, gi\|... - gi\|15802243\|ref\|NP_288266.1\| heat shock protein HtpX [Escherichia coli O157:H7 EDL933], gi\|12515876\|...	1.0E-66	[1..293]	[1..293]
gi\|254288677, gi... - gi\|254288677\|ref\|YP_003054425.1\| heat shock protein HtpX [Escherichia coli BL21(DE3)], gi\|253977984\|... gi\|83584508, gi\|... - gi\|83584508\|ref\|ZP_00923186.1\| COG0501: Zn-dependent protease with chaperone function [Escherichia c... gi\|242377550, gi... - gi\|251785277\|ref\|YP_002999581.1\| hypothetical protein B21_01788 [Escherichia coli BL21], gi\|24237755... gi\|254161889, gi... - gi\|254161889\|ref\|YP_003044997.1\| heat shock protein HtpX [Escherichia coli B str. REL606], gi\|253973...	2.0E-66	[1..293]	[1..293]
gi\|238798125, gi... - gi\|77961603\|ref\|ZP_00825437.1\| COG0501: Zn-dependent protease with chaperone function [Yersinia moll...	2.0E-66	[1..293]	[1..293]
gi\|89108669, gi\|... - gi\|89108669\|ref\|AP_002449.1\| predicted endopeptidase [Escherichia coli str. K-12 substr. W3110], gi\|... HTPX_ECOLI - Probable protease htpX (EC 3.4.24.-) (Heat shock protein htpX) - Escherichia coli EG10462 - putative endopeptidase / Zinc metalloprotease HtpX, membrane-bound; cleaves SecY in vivo and in vitr... HTPX_ECOBW - Protease HtpX OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=htpX PE=3 SV=1 HTPX_ECODH - Protease HtpX OS=Escherichia coli (strain K12 / DH10B) GN=htpX PE=3 SV=1 EG10462 - putative endopeptidase / Zinc metalloprotease HtpX, membrane-bound; cleaves SecY in vivo and in vitr...	2.0E-66	[1..293]	[1..293]

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Predicted Domain #1

Region A:
Residues: [1-70]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRIALFLLT NLAVMLVFGL VLSLTGIQSS SVQGLMIMAG LFGFGGAFVS LLMSKWMALR  60
   61 SVGGEVIERP

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	33.148742
Match:	PF06509.2
Description:	No description for PF06509.2 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [71-293]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNETEYWLLE TVRRQSQQVG IAMPQVAIYQ APDINAFATG ARRDASLVAV STGLLQNMSR  60
   61 DEAEAVIAHE ISHVANGDMV TMTLIQGVVN TFVIFISRLI AQIAAGFLSG DRDGESNSPG 120
  121 NPMVYFAVSM VLELVFGILA SIITMWFSRH REFHADAGSA KLVGREKMIA ALQRLKTSYE 180
  181 PQEAGSMMAF CINGKSKTFS ELFMSHPPLD KRIEALRSGQ YLK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.955
Match:	2qr4A
Description:	No description for 2qr4A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits