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View Structure Prediction Details

Protein: gi|123994061, gi...
Organism: synthetic construct
Length: 417 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|123994061, gi....

Description E-value Query
Range
Subject
Range
CBPB1_BOVIN - Carboxypeptidase B OS=Bos taurus GN=CPB1 PE=1 SV=2
0.0 [1..417] [1..417]
gi|61369719, gi|... - gi|61369724|gb|AAX43381.1| carboxypeptidase B1 [synthetic construct], gi|61369719|gb|AAX43380.1| car...
0.0 [1..417] [1..417]
gi|2960072 - gi|2960072|emb|CAA12163.1| procarboxypeptidase B [Homo sapiens]
0.0 [1..417] [1..417]
gi|109048836 - gi|109048836|ref|XP_001110220.1| PREDICTED: pancreatic carboxypeptidase B1 isoform 3 [Macaca mulatta...
0.0 [1..417] [1..417]
CBPB1_PIG - Carboxypeptidase B OS=Sus scrofa GN=CPB1 PE=1 SV=5
0.0 [1..416] [1..416]
gi|114589729, gi... - gi|114589731|ref|XP_516808.2| PREDICTED: pancreatic carboxypeptidase B1 isoform 5 [Pan troglodytes],...
0.0 [1..417] [1..417]
gi|20864725, gi|... - gi|56550071|ref|NP_083982.1| pancreatic carboxypeptidase B1 [Mus musculus], ref|XP_130814.1| carboxy...
0.0 [16..417] [14..415]
CBPB1_CANLF - Carboxypeptidase B OS=Canis lupus familiaris GN=CPB1 PE=2 SV=1
0.0 [2..417] [1..416]

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Predicted Domain #1
Region A:
Residues: [1-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLALLVLVTV ALASAHHGGE HFEGEKVFRV NVEDENHINI IRELASTTQI DFWKPDSVTQ  60
   61 IKPHSTVDFR VKAEDTVTVE NVLKQNELQY KVLISNLRNV VEAQFDSRVR ATGHSYEKYN 120
  121 KWETIEAWTQ QVATENPALI SRSVIGTTFE GRAIYLLKVG KAGQNKPAIF MDCGFHAREW 180
  181 ISPAFCQWFV REAVRTYGRE IQVTELLDKL DFYVLPVLNI DGYIYTWTKS RFWRKTRSTH 240
  241 TGSSCIGTDP NRNFDAGWCE IGASRNPCDE TYCGPAAESE KETKALADFI RNKLSSIKAY 300
  301 LTIHSYSQMM IYPYSYAYKL GENNAELNAL AKATVKELAS LHGTKYTYGP GATTIYPAAG 360
  361 GSDDWAYDQG IRYSFTFELR DTGRYGFLLP ESQIRATCEE TFLAIKYVAS YVLEHLY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 133.0
Match: 1kwmA
Description: Carboxypeptidase B; Procarboxypeptidase B
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.786910294594 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.40766568731738 bayes_pls_golite062009
hydrolase activity 4.23257784904124 bayes_pls_golite062009
exopeptidase activity 3.28577934113028 bayes_pls_golite062009
metallopeptidase activity 2.76103081380105 bayes_pls_golite062009
carboxypeptidase activity 2.63658263814587 bayes_pls_golite062009
metalloexopeptidase activity 1.76058821499096 bayes_pls_golite062009
metallocarboxypeptidase activity 1.56827526553175 bayes_pls_golite062009
catalytic activity 1.3989281287879 bayes_pls_golite062009
binding 1.13031326446259 bayes_pls_golite062009
endopeptidase activity 0.910234727191613 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 0.723243947871592 bayes_pls_golite062009
serine hydrolase activity 0.596149133958797 bayes_pls_golite062009
serine-type peptidase activity 0.578572340123331 bayes_pls_golite062009
nucleic acid binding 0.454707207494165 bayes_pls_golite062009
transcription regulator activity 0.273337363793137 bayes_pls_golite062009
DNA binding 0.115087846898245 bayes_pls_golite062009
aminopeptidase activity 0.0966237570696103 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle