YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|60813994, gi\|...
Organism:	synthetic construct
Length:	212 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|60813994, gi|....

Description	E-value	Query Range	Subject Range
gi\|542176652\|ref... - PREDICTED: programmed cell death protein 10 [Zonotrichia albicollis] PDC10_CHICK - Programmed cell death protein 10 OS=Gallus gallus GN=PDCD10 PE=2 SV=1 gi\|224060913 - gi\|224060913\|ref\|XP_002198418.1\| PREDICTED: programmed cell death 10 [Taeniopygia guttata]	2.0E-97	[1..212]	[1..212]
gi\|149731072, gi... - gi\|149731076\|ref\|XP_001490726.1\| PREDICTED: similar to Programmed cell death 10 isoform 1 [Equus cab... gi\|149633324 - gi\|149633324\|ref\|XP_001505604.1\| PREDICTED: similar to Programmed cell death 10 [Ornithorhynchus ana... ENSCJAT00000005295 - null gi\|76607795, gi\|... - gi\|76607795\|ref\|XP_880205.1\| PREDICTED: similar to programmed cell death 10 isoform 5 [Bos taurus], ... gi\|90081906 - gi\|90081906\|dbj\|BAE90234.1\| unnamed protein product [Macaca fascicularis] PDC10_MOUSE - Programmed cell death protein 10 OS=Mus musculus GN=Pdcd10 PE=1 SV=1 gi\|57110102 - gi\|57110102\|ref\|XP_545269.1\| PREDICTED: similar to programmed cell death 10 isoform 1 [Canis familia... gi\|126338381 - gi\|126338381\|ref\|XP_001362899.1\| PREDICTED: similar to Programmed cell death 10 [Monodelphis domesti... gi\|109044492, gi... - gi\|109044495\|ref\|XP_001095337.1\| PREDICTED: similar to programmed cell death 10 isoform 3 [Macaca mu...	2.0E-97	[1..212]	[1..212]
gi\|61371676, gi\|... - gi\|61371676\|gb\|AAX43711.1\| programmed cell death 10 [synthetic construct], gi\|61368165\|gb\|AAX43118.1...	2.0E-97	[1..212]	[1..212]
gi\|2465729 - gi\|2465729\|gb\|AAB72225.1\| TFAR15 [Homo sapiens]	1.0E-96	[1..212]	[1..212]
PD10B_DANRE - Programmed cell death protein 10-B OS=Danio rerio GN=pdcd10b PE=1 SV=1	8.0E-96	[3..212]	[1..210]
PDC10_XENLA - Programmed cell death protein 10 OS=Xenopus laevis GN=pdcd10 PE=2 SV=1	9.0E-96	[1..212]	[1..212]
gi\|55742276 - ref\|NP_001006850.1\| programmed cell death 10 [Xenopus tropicalis] PDC10_XENTR - Programmed cell death protein 10 OS=Xenopus tropicalis GN=pdcd10 PE=2 SV=1	2.0E-95	[1..212]	[1..212]
PDC10_RAT - Programmed cell death protein 10 OS=Rattus norvegicus GN=Pdcd10 PE=2 SV=1	2.0E-95	[3..212]	[1..210]

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Predicted Domain #1

Region A:
Residues: [1-98]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRMTMEEMKN EAETTSMVSM PLYAVMYPVF NELERVNLSA AQTLRAAFIK AEKENPGLTQ  60
   61 DIIMKILEKK SVEVNFTESL LRMAADDVEE YMIERPEP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.694	0.060	protein binding	a.74.1	Cyclin-like
View	Download	0.587	0.005	apoptosis	a.52.1	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View	Download	0.542	0.000	apoptosis	a.5.6	Hypothetical protein MTH1615
View	Download	0.522	0.000	apoptosis	a.23.4	Mitochondrial import receptor subunit Tom20
View	Download	0.540	N/A	N/A	a.52.1	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin

Predicted Domain #2

Region A:
Residues: [99-212]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFQDLNEKAR ALKQILSKIP DEINDRVRFL QTIKDIASAI KELLDTVNNV FKKYQYQNRR  60
   61 ALEHQKKEFV KYSKSFSDTL KTYFKDGKAI NVFVSANRLI HQTNLILQTF KTVA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.967	0.003	apoptosis	a.24.14	FAT domain of focal adhesion kinase
View	Download	0.966	0.003	apoptosis	a.24.3	Cytochromes
View	Download	0.972	0.003	apoptosis	f.14.1	Voltage-gated potassium channels
View	Download	0.967	0.003	apoptosis	a.24.16	Nucleotidyltransferase substrate binding subunit/domain
View	Download	0.961	0.003	apoptosis	a.24.3	Cytochromes

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits