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View Structure Prediction Details

Protein: CG4673-PD, CG4673-PB
Organism: Drosophila melanogaster
Length: 624 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG4673-PD, CG4673-PB.

Description E-value Query
Range
Subject
Range
NPLOC4 - nuclear protein localization 4 homolog (S. cerevisiae)
gi|123997361 - gi|123997361|gb|ABM86282.1| nuclear protein localization 4 homolog (S. cerevisiae) [synthetic constr...
898.0 [0..3] [624..2]

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Predicted Domain #1
Region A:
Residues: [1-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNDKILIRV QSAEGIKRIE ISPKSNLKHL YDSVQNALKV DGFGLFKERN FLTELQASGS  60
   61 QLVGTSLRHG DMVYLKQMAG TSSRRTSTTV LDSQAFKTST ISNPNSARPS FNVIEDDVDQ 120
  121 ALSKADGTIK RERDSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.30103
Match: 1wf9A
Description: Solution structure of a novel beta-grasp fold like domain of Hypothetical protein (Arabidopsis thaliana)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 6.3238498800949 bayes_pls_golite062009
ubiquitin-protein ligase activity 5.759996473289 bayes_pls_golite062009
acid-amino acid ligase activity 5.32190918602578 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 4.23828791893907 bayes_pls_golite062009
binding 2.5881743465274 bayes_pls_golite062009
ligase activity 2.25858205355159 bayes_pls_golite062009
protein binding 1.76858817153382 bayes_pls_golite062009
hydrolase activity 0.614233748923048 bayes_pls_golite062009
signal transducer activity 0.5176352635445 bayes_pls_golite062009
molecular transducer activity 0.5176352635445 bayes_pls_golite062009
nucleic acid binding 0.383121378043805 bayes_pls_golite062009
cytoskeletal protein binding 0.366426020658587 bayes_pls_golite062009
transcription regulator activity 0.273912905624139 bayes_pls_golite062009
DNA binding 0.0840213088061073 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [137-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LCHHNANGRC VHCSALEPYD ESYLKEHNIK HLSFHSYIRK QTSGMDQGKY FV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [189-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FDDINCRIKP GCREHPPWPK GICSKCQPSA ITLNRQTYRH VDNVMFENTK IVERFLNYWR  60
   61 TTGHQRMGYL YGTYEQHTDV PLGIRAKVAA IYEPPQESTR DSINIQPDEF ADDVDAVASA 120
  121 LGLKKIGWIF TDLITDDASI GTVKQIRGIE SHFITAQECI TAGELQNRHP NPCKYASNGV 180
  181 FGSKFVTICV TGDKTKQVHM EGYAVSAQCM ALVRDNCLIP TKDAPELGYV RESTDKQYVP 240
  241 DVFYKEKDLY GNEVQRLARP LPVEYLLVDV PASTPLQPIY TFTEYDKRQP FPIENRYIDG 300
  301 HLQDFNALSC YLSAWGEEEF LEAISD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.8
Match: 2og4A
Description: No description for 2og4A was found.

Predicted Domain #4
Region A:
Residues: [515-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FHLLVYLYKM DMLPLRQHMG PLLEAVRTKN PNQAAQFKVV DVWKLLESLI QASSGGSGGT  60
   61 TSYPSGGASA SAGASGSEAM DLDANTWTCN HCTFINRGEL TSCEICSLPR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle