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View Structure Prediction Details

Protein: JMJD4
Organism: Homo sapiens
Length: 463 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for JMJD4.

Description E-value Query
Range
Subject
Range
gi|10434049, gi|... - gi|12711670|ref|NP_075383.1| jumonji domain containing 4 [Homo sapiens], gi|10434049|dbj|BAB14109.1|...
0.0 [1..463] [1..463]
gi|114572991 - gi|114572991|ref|XP_001143331.1| PREDICTED: jumonji domain containing 4 isoform 2 [Pan troglodytes]
0.0 [1..463] [1..463]
gi|109017986 - gi|109017986|ref|XP_001086580.1| PREDICTED: similar to jumonji domain containing 4 isoform 2 [Macaca...
0.0 [1..463] [1..463]
gi|149052799, gi... - gi|157786610|ref|NP_001099254.1| jumonji domain containing 4 [Rattus norvegicus], gi|149052799|gb|ED...
0.0 [47..462] [1..425]
JMJD4_MOUSE - JmjC domain-containing protein 4 OS=Mus musculus GN=Jmjd4 PE=2 SV=1
0.0 [47..462] [1..426]

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Predicted Domain #1
Region A:
Residues: [1-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRAGPEPQAL AGQKRGALRL LVPRLVLTVS APAEVRRRVL RPVLSWMDRE TRALADSHFR  60
   61 GLGVDVPGVG QAPGRVAFVS EPGAFSYADF VRGFLLPNLP CVFSSAFTQG WGSRRRWVTP 120
  121 AGRPDFDHLL RTYGDVVVPV ANCGVQEYNS NPKEHMTLRD YITYWKEYIQ AGYSSPRGCL 180
  181 YLKDWHLCRD FPVEDVFTLP VYFSSDWLNE FWDALDVDDY RFVYAGPAGS WSPFHADIFR 240
  241 SFSWSVNVCG RKKWLLFPPG QEEALRDRHG NLPYDVTSPA LCDTHLHPRN QLAGPPLEIT 300
  301 QEAGEMVFVP SGWHHQVHNL DDTISINHNW V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.69897
Match: 1mzeA
Description: Hypoxia-inducible factor HIF ihhibitor (FIH1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.642934433547624 bayes_pls_golite062009
protein binding 0.0678897223734009 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [332-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGFNLANMWR FLQQELCAVQ EEVSEWRDSM PDWHHHCQVI MRSCSGINFE EFYHFLKVIA  60
   61 EKRLLVLREA AAEDGAGLGF EQAAFDVGRI TEVLASLVAH PDFQRVDTSA FSPQPKELLQ 120
  121 QLREAVDAAA AP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.39
Match: 2yu1A
Description: No description for 2yu1A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle