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View Structure Prediction Details

Protein: AI2
Organism: Saccharomyces cerevisiae
Length: 854 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AI2.

Description E-value Query
Range
Subject
Range
gi|22797123 - gi|22797123|emb|CAD22263.1| maturase [Paracryphia alticola]
723.0 [0..267] [787..1]

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Predicted Domain #1
Region A:
Residues: [1-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG NSQLFNVLVV  60
   61 GHAVLMIFCA PFRLIYHCIE VLIDKHISVY SINENFTVSF WFWLLVVTYM VFRYVNHMAY 120
  121 PVGANSTGTM ACHKSAGVKQ PAQGKNCPMA RLTNSCKECL GFSLTPSHLG IVIHAYVLEE 180
  181 EVHELTKNES LALSKSWHLE GCTSSNGKLR NTGLSERGNP GDNGVFMVPK FNLNKVRYFS 240
  241 TLSKLNARKE DSLAYLTKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 89.522879
Match: 1occA
Description: Mitochondrial cytochrome c oxidase, subunit I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
heme-copper terminal oxidase activity 5.45481380399883 bayes_pls_golite062009
cytochrome-c oxidase activity 5.0434003897137 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 5.0434003897137 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 5.0434003897137 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 4.67498134749296 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 4.49704329043685 bayes_pls_golite062009
oxidoreductase activity 4.31093171497983 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 3.74570258984477 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 2.92202780814066 bayes_pls_golite062009
cation transmembrane transporter activity 2.43526852804891 bayes_pls_golite062009
ion transmembrane transporter activity 2.24124755133579 bayes_pls_golite062009
catalytic activity 1.95966890211023 bayes_pls_golite062009
binding 0.733970829597091 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [260-707]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTTDFSELNK LMENNHNKTE TINTRILKLM SDIRMLLIAY NKIKSKKGNM SKGSNNITLD  60
   61 GINISYLNKL SKDINTNMFK FSPVRRVEIP KTSGGFRPLS VGNPREKIVQ ESMRMMLEII 120
  121 YNNSFSYYSH GFRPNLSCLT AIIQCKNYMQ YCNWFIKVDL NKCFDTIPHN MLINVLNERI 180
  181 KDKGFMDLLY KLLRAGYVDK NNNYHNTTLG IPQGSVVSPI LCNIFLDKLD KYLENKFENE 240
  241 FNTGNMSNRG RNPIYNSLSS KIYRCKLLSE KLKLIRLRDH YQRNMGSDKS FKRAYFVRYA 300
  301 DDIIIGVMGS HNDCKNILND INNFLKENLG MSINMDKSVI KHSKEGVSFL GYDVKVTPWE 360
  361 KRPYRMIKKG DNFIRVRHHT SLVVNAPIRS IVMKLNKHGY CSHGILGKPR GVGRLIHEEM 420
  421 KTILMHYLAV GRGIMNYYRL ATNFTTLR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.24
Match: 1xr7A
Description: Crystal structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 16
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA polymerase activity 3.48899522091554 bayes_pls_golite062009
DNA-directed DNA polymerase activity 3.47530593895491 bayes_pls_golite062009
nucleotidyltransferase activity 1.44935357223617 bayes_pls_golite062009
DNA binding 1.04980164056055 bayes_pls_golite062009
catalytic activity 0.985794797454925 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.977829931092877 bayes_pls_golite062009
nucleic acid binding 0.916757424850137 bayes_pls_golite062009
binding 0.826541132106647 bayes_pls_golite062009
transferase activity 0.562916058192021 bayes_pls_golite062009
exonuclease activity 0.478231141372817 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [708-854]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRITYILFYS CCLTLARKFK LNTVKKVILK FGKVLVDPHS KVSFSIDDFK IRHKMNMTDS  60
   61 NYTPDEILDR YKYMLPRSLS LFSGICQICG SKHDLEVHHV RTLNNAANKI KDDYLLGRMI 120
  121 KMNRKQITIC KTCHFKVHQG KYNGPGL

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 10.638272
Match: PF01348.12
Description: No description for PF01348.12 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle