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View Structure Prediction Details

Protein: YIH1
Organism: Saccharomyces cerevisiae
Length: 258 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIH1.

Description E-value Query
Range
Subject
Range
IMPCT_XENLA - Protein IMPACT OS=Xenopus laevis GN=impact PE=2 SV=1
2.0E-92 [2..258] [6..293]
YIH1 - Protein that inhibits activation of Gcn2p, an eIF2 alpha subunit protein kinase, by competing for Gc...
gi|151943874 - gi|151943874|gb|EDN62174.1| conserved protein [Saccharomyces cerevisiae YJM789]
gi|207347270 - gi|207347270|gb|EDZ73503.1| YCR059Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190406483 - gi|190406483|gb|EDV09750.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
YIH1_YEAST - Protein IMPACT homolog OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YIH1 PE=1 SV=1
2.0E-92 [1..258] [1..258]
IMPCT_MOUSE - Protein IMPACT OS=Mus musculus GN=Impact PE=1 SV=2
1.0E-85 [4..256] [8..293]
gi|4996357 - gi|4996357|dbj|BAA78421.1| unnamed protein product [Xenopus borealis]
1.0E-84 [2..258] [3..290]
IMPACT - Impact homolog (mouse)
gi|123992930, gi... - gi|157928552|gb|ABW03572.1| Impact homolog (mouse) [synthetic construct], gi|123992930|gb|ABM84067.1...
3.0E-84 [6..256] [10..294]
YIH1_SCHPO - Protein IMPACT homolog OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=yih1 PE=3 SV=1
SPAC27E2.02 - IMPACT homolog
2.0E-67 [3..252] [2..260]
gi|14973721, gi|... - gi|66878383|ref|ZP_00403866.1| COG1739: Uncharacterized conserved protein [Streptococcus pneumoniae ...
gi|25303433 - pir||C95258 conserved hypothetical protein SP2209 [imported] - Streptococcus pneumoniae (strain TIGR...
1.0E-37 [130..255] [5..126]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-37 [138..251] [13..124]

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Predicted Domain #1
Region A:
Residues: [1-108]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDDHEQLVE ELEAVEAIYP DLLSKKQEDG SIIVVKVPQH EYMTLQISFP THYPSEEAPN  60
   61 VIEVGVCTSL AKRDLYDTKY LQHLFQEVMD SVFHRGSVCL FDFLTELD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [109-258]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVLYVEPEEE TEPVQQSDIP TDPFEGWTAS DPITDRGSTF MAFAAHVTSE EQAFAMLDLL  60
   61 KTDSKMRKAN HVMSAWRIKQ DGSAATYQDS DDDGETAAGS RMLHLITIMD VWNVIVVVAR 120
  121 WFGGAHIGPD RFKHINSTAR EAVVRAGFDS 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 62.853872
Match: PF01205
Description: Uncharacterized protein family UPF0029

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transferase activity, transferring phosphorus-containing groups 2.55433995647388 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 2.26982378355508 bayes_pls_golite062009
3'-5'-exoribonuclease activity 2.17994566452938 bayes_pls_golite062009
kinase activity 2.16946639423557 bayes_pls_golite062009
structural constituent of ribosome 2.0116317330767 bayes_pls_golite062009
transcription regulator activity 1.90728659801871 bayes_pls_golite062009
structural molecule activity 1.77722756041008 bayes_pls_golite062009
nucleic acid binding 1.75408506104351 bayes_pls_golite062009
DNA binding 1.50208874269692 bayes_pls_golite062009
binding 1.50032731466041 bayes_pls_golite062009
transferase activity 1.25037643378444 bayes_pls_golite062009
catalytic activity 0.878454819018611 bayes_pls_golite062009
ribonuclease activity 0.825588323751637 bayes_pls_golite062009
nuclease activity 0.234623495149702 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 0.21915720954962 bayes_pls_golite062009
exoribonuclease activity 0.20391251413344 bayes_pls_golite062009
protein binding 0.191135371876197 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle