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View Structure Prediction Details

Protein: GAL83
Organism: Saccharomyces cerevisiae
Length: 417 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAL83.

Description E-value Query
Range		 Subject
Range
GAL83_YEAST - SNF1 protein kinase subunit beta-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GAL83...
GAL83 - One of three possible beta-subunits of the Snf1 kinase complex, allows nuclear localization of the S...
 0.0 [1..417] [1..417]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 3.0E-92 [9..417] [24..486]
gi|7433849 - pir||S76095 hypothetical protein - Synechocystis sp. (strain PCC 6803)
GLGB_SYNY3 - 1,4-alpha-glucan branching enzyme GlgB OS=Synechocystis sp. (strain PCC 6803 / Kazusa) GN=glgB PE=3 ...
GLGB_SYNY3 - 1,4-alpha-glucan branching enzyme GlgB OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1) GN=...
 2.0E-67 [124..380] [105..375]
gi|25286746 - pir||AG1895 1,4-alpha-glucan branching enzyme [imported] - Nostoc sp. (strain PCC 7120)
GLGB_NOSS1 - 1,4-alpha-glucan branching enzyme GlgB OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=glgB PE=3 SV=1
 1.0E-63 [126..380] [107..376]
GLGB_AQUAE - 1,4-alpha-glucan branching enzyme GlgB OS=Aquifex aeolicus GN=glgB PE=3 SV=1
GLGB_AQUAE - 1,4-alpha-glucan branching enzyme GlgB OS=Aquifex aeolicus (strain VF5) GN=glgB PE=3 SV=1
 4.0E-63 [136..380] [15..253]
GLGB_BACCL - 1,4-alpha-glucan branching enzyme GlgB OS=Bacillus caldolyticus GN=glgB PE=1 SV=1
 1.0E-62 [145..380] [21..251]
GLGB2_STRCO, GLB... - 1,4-alpha-glucan branching enzyme GlgB 2 OS=Streptomyces coelicolor GN=glgB2 PE=3 SV=2, (Q59832) 1,4...
GLGB2_STRCO - 1,4-alpha-glucan branching enzyme GlgB 2 OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M...
 6.0E-62 [114..377] [108..360]
GLGB_SYNP6 - 1,4-alpha-glucan branching enzyme GlgB OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 140...
GLGB_SYNE7 - 1,4-alpha-glucan branching enzyme GlgB OS=Synechococcus elongatus (strain PCC 7942) GN=glgB PE=1 SV=...
gi|97560 - pir||JQ0550 1,4-alpha-glucan branching enzyme (EC 2.4.1.18) - Synechococcus sp. (strain PCC 7942)
 1.0E-61 [126..380] [113..382]

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Predicted Domain #1
Region A:
Residues: [1-130] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGDNPENKD ASMLDVSDAA SNTTINGKHS ADSTNEASLA YTFSQMNVDN PNELEPQHPL  60
   61 RHKSSLIFND DDDDEIPPYS NHAENGSGET FDSDDDIDAS SSSSIDSNEG DIHDADMTGN 120
  121 TLQKMDYQPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [131-225] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQPDSLQNQG FQQQQEQQQG TVEGKKGRAM MFPVDITWQQ GGNKVYVTGS FTGWRKMIGL  60
   61 VPVPGQPGLM HVKLQLPPGT HRFRFIVDNE LRFSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.69897
Match: 1eh9A_
Description: Glycosyltrehalose trehalohydrolase, N-terminal domain N; Glycosyltrehalose trehalohydrolase; Glycosyltrehalose trehalohydrolase, central domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
AMP-activated protein kinase activity 4.78975226545815 bayes_pls_golite062009
binding 2.65544526722793 bayes_pls_golite062009
cation transmembrane transporter activity 1.69105818607475 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.66390525860632 bayes_pls_golite062009
kinase activity 1.64560031716993 bayes_pls_golite062009
voltage-gated potassium channel activity 1.62236890256061 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.53194692728729 bayes_pls_golite062009
protein binding 1.50286160643298 bayes_pls_golite062009
protein kinase activity 1.44964326848891 bayes_pls_golite062009
ion transmembrane transporter activity 1.39709424453076 bayes_pls_golite062009
transferase activity 1.26709925711174 bayes_pls_golite062009
cation channel activity 1.10928620793874 bayes_pls_golite062009
ligand-gated ion channel activity 1.08920948133636 bayes_pls_golite062009
ligand-gated channel activity 1.08920948133636 bayes_pls_golite062009
gated channel activity 0.9831902560942 bayes_pls_golite062009
ion channel activity 0.88499192552319 bayes_pls_golite062009
protein serine/threonine kinase activity 0.726369450752205 bayes_pls_golite062009
cytoskeletal protein binding 0.60798225319459 bayes_pls_golite062009
actin binding 0.54002000529721 bayes_pls_golite062009
enzyme binding 0.37496592438035 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [226-417] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YLPTATDQMG NFVNYMEVSA PPDWGNEPQQ HLAEKKANHV DDSKLSKRPM SARSRIALEI  60
   61 EKEPDDMGDG YTRFHDETPA KPNLEYTQDI PAVFTDPNVM EQYYLTLDQQ QNNHQNMAWL 120
  121 TPPQLPPHLE NVILNSYSNA QTDNTSGALP IPNHVILNHL ATSSIKHNTL CVASIVRYKQ 180
  181 KYVTQILYTP LQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.69897
Match: 1eh9A_
Description: Glycosyltrehalose trehalohydrolase, N-terminal domain N; Glycosyltrehalose trehalohydrolase; Glycosyltrehalose trehalohydrolase, central domain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle